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anti-1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) Antibodies

AGPAT2 encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. Additionally we are shipping AGPAT2 Kits (23) and AGPAT2 Proteins (4) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AGPAT2 10555 O15120
AGPAT2 311821  
AGPAT2 67512 Q8K3K7
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Top anti-AGPAT2 Antibodies at antibodies-online.com

Showing 10 out of 37 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-AGPAT2 Antibody Titration: 5.0ug/mlPositive Control:... 100 μL Log in to see 2 to 3 Days
$229.00
Details
Human Rabbit Un-conjugated EIA, WB 10 blots Log in to see 6 to 8 Days
$533.50
Details
Human Rabbit Un-conjugated WB 100 μg Log in to see 8 to 10 Days
$493.17
Details
Human Rabbit Un-conjugated ELISA, WB 100 μg Log in to see 2 to 3 Days
$343.75
Details
Human Rabbit Un-conjugated IHC, ELISA   100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of AGPAT2 expression in transfected 293T cell li... 50 μL Log in to see 9 Days
$430.00
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (33.48 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Biotin IHC (p), WB   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit FITC IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

AGPAT2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Rat (Rattus) , , ,

Mouse (Murine) , , ,

Top referenced anti-AGPAT2 Antibodies

  1. Human Polyclonal AGPAT2 Primary Antibody for EIA, WB - ABIN265083 : West, Tompkins, Balantac, Nudelman, Meengs, White, Bursten, Coleman, Kumar, Singer, Leung: Cloning and expression of two human lysophosphatidic acid acyltransferase cDNAs that enhance cytokine-induced signaling responses in cells. in DNA and cell biology 1997 (PubMed)
    Show all 6 references for ABIN265083

  2. Human Polyclonal AGPAT2 Primary Antibody for WB - ABIN2781951 : Niesporek, Denkert, Weichert, Köbel, Noske, Sehouli, Singer, Dietel, Hauptmann: Expression of lysophosphatidic acid acyltransferase beta (LPAAT-beta) in ovarian carcinoma: correlation with tumour grading and prognosis. in British journal of cancer 2005 (PubMed)

More Antibodies against AGPAT2 Interaction Partners

Human 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Data show that missense mutation c.299G>A changes serine in the acyltransferase NHX4D motif of AGPAT2, and intronic c.493-1G>C mutation destroy a splicing site that leads to exon 4 skipping and deletion of whole AGPAT2 substrate binding domain.

  2. the ability of LPAAT-beta to regulate mTOR (show FRAP1 Antibodies) function

  3. miR (show MLXIP Antibodies)-24 may play an important role in inhibiting osteosarcoma growth through suppression of LPAATbeta.

  4. Data suggest that AGPAT2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K (show PIK3CA Antibodies))/protooncogene c-Akt (show AKT1 Antibodies) and PPARgamma (show PPARG Antibodies) signaling in early stage of adipogenesis.

  5. the role of AGPAT1 (show AGPAT1 Antibodies) or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin (show INS Antibodies) resistance

  6. lpaat beta gene overexpression exists in both AML (show RUNX1 Antibodies) and CML (show BCR Antibodies) patients. lpaat beta produced by AML (show RUNX1 Antibodies) cells probably plays an important role in abnormal proliferation and drug-resistance of AML (show RUNX1 Antibodies) cells.

  7. Lysophosphatidic acid acyltransferase beta (LPAATbeta) promotes the tumor growth of human osteosarcoma

  8. AGPAT2 is mutated in congenital generalized lipodystrophy linked to chromosome 9q34.

  9. Congenital lipodystrophy patients with Seipin (show BSCL2 Antibodies) mutations have a more severe lack of body fat, which affects both metabolically active and mechanical adipose tissue, compared with patients with mutations in the AGPAT2 gene.

  10. mutations in AGPAT2 and Gng3lg (show BSCL2 Antibodies) are approximately equally represented in congenital generalized lipodystrophy

Cow (Bovine) 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Data indicate that the longissimus dorsi muscle (LM) of steers showed higher G0/G1 switch gene 2 (G0S2 (show G0S2 Antibodies)) and comparative gene identification-58 (CGI-58 (show ABHD5 Antibodies)) mRNA expression levels than the LM of bulls.

Mouse (Murine) 1-Acylglycerol-3-Phosphate O-Acyltransferase 2 (Lysophosphatidic Acid Acyltransferase, Beta) (AGPAT2) interaction partners

  1. Adipogenically induced Agpat2(-/-) preadipocytes had fewer lipid-loaded cells and lower levels of adipocyte markers than wild type preadipocytes.

  2. Leptin (show LEP Antibodies) ameliorates insulin (show INS Antibodies) resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin (show LEP Antibodies) receptors

  3. The lack of normal insulin (show INS Antibodies) signaling in Agpat2(-/-) livers allows unrestricted phosphatidic acid-induced gluconeogenesis.

  4. Data suggest that Agpat2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K)/protooncogene c-Akt (show AKT1 Antibodies) and PPARgamma (show PPARG Antibodies) signaling in early stage of adipogenesis.

  5. the role of AGPAT1 (show AGPAT1 Antibodies) or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin (show INS Antibodies) resistance

  6. Loss of adipocytes by necrosis and apoptosis in Agpat2 null mice

  7. impaired AGPAT2 activity affects availability of phosphatidic acid (PA) for triacylglycerol synthesis but not overall PA synthesis nor utilization of PA for phospholipid synthesis

  8. The alternative monoacylglycerol pathway for triglyceride biosynthesis is activated in the absence of 1-acylglycerol-3-phosphate O-acyltransferase 2.

AGPAT2 Antigen Profile

Protein Summary

This gene encodes a member of the 1-acylglycerol-3-phosphate O-acyltransferase family. The protein is located within the endoplasmic reticulum membrane and converts lysophosphatidic acid to phosphatidic acid, the second step in de novo phospholipid biosynthesis. Mutations in this gene have been associated with congenital generalized lipodystrophy (CGL), or Berardinelli-Seip syndrome, a disease characterized by a near absence of adipose tissue and severe insulin resistance. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with AGPAT2

  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (AGPAT2) antibody
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (agpat2) antibody
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (agpat2) antibody
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (AGPAT2) antibody
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (Agpat2) antibody
  • 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) (Agpat2) antibody
  • 1-AGPAT2 antibody
  • 2510002J07Rik antibody
  • AGPAT2 antibody
  • AV000834 antibody
  • BSCL antibody
  • BSCL1 antibody
  • LPAAB antibody
  • LPAAT-beta antibody
  • zgc:153984 antibody

Protein level used designations for AGPAT2

1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta) , 1-acyl-sn-glycerol-3-phosphate acyltransferase alpha , 1-AGP acyltransferase 2 , 1-AGPAT 2 , 1-acyl-sn-glycerol-3-phosphate acyltransferase beta , lysophosphatidic acid acyltransferase beta , lysophosphatidic acid acyltransferase-beta , lysophosphatidic acid acyltransferase, beta

GENE ID SPECIES
709753 Macaca mulatta
748669 Pan troglodytes
772114 Gallus gallus
777624 Danio rerio
100170486 Xenopus (Silurana) tropicalis
10555 Homo sapiens
311821 Rattus norvegicus
491249 Canis lupus familiaris
100170768 Sus scrofa
512112 Bos taurus
67512 Mus musculus
101114511 Ovis aries
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