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The protein encoded by AGPAT3 is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. Additionally we are shipping 1-Acylglycerol-3-Phosphate O-Acyltransferase 3 Kits (12) and 1-Acylglycerol-3-Phosphate O-Acyltransferase 3 Proteins (8) and many more products for this protein.
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enzymatic properties, tissue distribution, and subcellular localization of human AGPAT3 and AGPAT5 (show AGPAT5 Antibodies)
The data is consistent with a structural arrangement in which motif I is located in the cytoplasm and motif II is in the endoplasmic reticulum and Golgi lumen, suggesting a different model for AGPAT3/LPAAT3's enzymatic mechanism.
Of the two well conserved acyltransferase motifs, NHX(4)D is present in AGPAT8 (show AGPAT9 Antibodies), whereas arginine in the EGTR motif is substituted by aspartate.
Results report the identification of an integral membrane lysophosphatidic acid-specific acyltransferase, LPAAT3, which regulates Golgi membrane tubule formation, trafficking, and structure by altering phospholipids and lysophospholipids.
The induction of LPAAT3 during germ cell development critically contributes to the accumulation of PUFAs in testicular phospholipids, thereby possibly affecting sperm cell production.
The protein encoded by this gene is an acyltransferase that converts lysophosphatidic acid into phosphatidic acid, which is the second step in the de novo phospholipid biosynthetic pathway. The encoded protein may be an integral membrane protein. Two transcript variants encoding the same protein have been found for this gene.
1-AGP acyltransferase 3
, 1-AGPAT 3
, 1-acyl-sn-glycerol-3-phosphate acyltransferase gamma
, lysophosphatidic acid acyltransferase gamma
, lysophosphatidic acid acyltransferase-gamma1
, lysophosphatidic acid acyltransferase 3