2',3'-Cyclic Nucleotide 3' phosphodiesterase Proteins (CNP)

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).. Additionally we are shipping Cnpase Antibodies (129) and Cnpase Kits (13) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
CNP 1267 P09543
CNP 12799 P16330
Rat CNP CNP 25275 P13233
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Top Cnpase Proteins at antibodies-online.com

Showing 6 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
Details
Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 50 Days
$5,442.50
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HEK-293 Cells Human Myc-DYKDDDDK Tag Validation with Western Blot 20 μg Log in to see 10 to 12 Days
$785.40
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Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Escherichia coli (E. coli) Human T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$560.00
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Escherichia coli (E. coli) Mouse T7 tag,His tag   100 μg Log in to see 15 to 18 Days
$608.00
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CNP Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , ,
, , ,
Mouse (Murine) ,
,

Top referenced Cnpase Proteins

  1. Human Cnpase Protein expressed in Wheat germ - ABIN1349874 : Kandadai, Mok, Ali, Li: Characterization of an RNA-cleaving deoxyribozyme with optimal activity at pH 5. in Biochemistry 2009 (PubMed)

  2. Human Cnpase Protein expressed in HEK-293 Cells - ABIN2712913 : Verrier, Kochanek, Jackson: Schwann Cells Metabolize Extracellular 2',3'-cAMP to 2'-AMP. in The Journal of pharmacology and experimental therapeutics 2015 (PubMed)

More Proteins for 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) Interaction Partners

Human 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) interaction partners

  1. This study showed that the expression of CNPase protein was significantly decreased but increase expression mrna in ventral prefrontal white matter in major depressive disorder.

  2. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

  3. No Alzheimer disease-associated differences in CNP and DPYSL2 (show DPYSL2 Proteins) promoter DNA methylation (show HELLS Proteins) were observed.

  4. CNP binds to the structural protein Gag and blocks HIV-1 particle assembly after Gag and viral RNA have associated with the plasma membrane.

  5. Differential CNP expression correlated with mouse model survival, and CNP immunoassay of a large GBM tissue microarray also showed significant differential patient survival

  6. The characteristic features in both humans and mice with their partial CNP 'loss-of-function' genotype are best described as 'catatonia-depression' syndrome.

  7. verified the molecular interaction of Nogo-A (show RTN4 Proteins) with 2', 3'-cyclic nucleotide 3'-phosphodiesterase (CNP), which could act as a conformational stabilizer for the intrinsically unstructured large segment of Amino-Nogo (show RTN4 Proteins)

  8. reduced CNP expression in the schizophrenic brain is relevant to disease etiology and therefore provide support for the general hypothesis that altered oligodendrocyte function is an etiological factor in schizophrenia.

  9. The crystal structure of the catalytic fragment of human CNP (hCNP (show PEBP1 Proteins)-CF) at 1.3 A resolution, is determined.

  10. study did not find an association between genetic variations in the CNP gene and schizophrenia in the Han Chinese population

Mouse (Murine) 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) interaction partners

  1. CNP directly associates with and organizes the actin cytoskeleton, thereby providing an intracellular strut that counteracts membrane compaction by myelin basic protein (MBP (show MBP Proteins)).

  2. E2-ERs system was functional in maintaining oocyte meiotic arrest by regulating the expression of natriuretic peptide C (show NPPC Proteins) and natriuretic peptide receptor 2 (NPPC (show NPPC Proteins)/NPR2 (show NPRL2 Proteins))

  3. Data show atomic-resolution details of 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase) catalytic domain active site.

  4. CNP activates bone turnover and remodeling in vivo and possibly accelerates fracture healing in a mouse model.

  5. The up-to-day world-wide data about the structure, distribution, and physiological effects of the most poorly known among the natriuretic peptides--the C-type (CNP)--are summarized in the review.

  6. Connexin mimetics directed against connexin-43 (Cx43 (show GJA1 Proteins) CMP (show MATN1 Proteins)) overcame NPPC (show NPPC Proteins)-mediated meiotic arrest in both isolated cumulus oocyte complexes and antral follicles.

  7. CNP/NPR-C (show NPR3 Proteins) pathway has potential as a disease-modifying therapeutic target for cardiovascular disorders

  8. kidneys express 2',3'-cyclic nucleotide 3'-phosphodiesterase (CNPase), and renal CNPase mediates in part the renal 2',3'-cAMP-adenosine pathway

  9. Data indicate an important, previously neglected, role of NEP (show MME Proteins) for regulation of luminal factors in the epididymis and suggest a novel role for CNP/guanylyl cyclase B in the epididymal epithelium

  10. The data of this study reveal that CNPase is a critically important enzyme in the 2',3'-cAMP-adenosine pathway and participates in the production of adenosine, a protective neuromodulator.

Zebrafish 2',3'-Cyclic Nucleotide 3' phosphodiesterase (CNP) interaction partners

Cnpase (CNP) Protein Profile

Protein Summary

May participate in RNA metabolism in the myelinating cell, CNP is the third most abundant protein in central nervous system myelin (By similarity).

Gene names and symbols associated with CNP

  • 2',3'-cyclic nucleotide 3' phosphodiesterase (CNP)
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (Cnp)
  • natriuretic peptide type C (Nppc)
  • natriuretic peptide C (NPPC)
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (cnp)
  • 2',3'-cyclic nucleotide 3' phosphodiesterase (cnp.L)
  • cnp protein
  • Cnp-1 protein
  • Cnp1 protein
  • CNP3 protein
  • CNPase protein
  • CNPF protein
  • CNPI protein
  • CNPII protein
  • cnpl protein
  • DKFZp469F1421 protein
  • fd21d08 protein
  • fi37a10 protein
  • lbab protein
  • rich protein
  • sb:cb662 protein
  • si:ch73-158e11.4 protein
  • wu:fd21d08 protein
  • wu:fd44a05 protein
  • wu:fi35d08 protein
  • wu:fi37a10 protein

Protein level used designations for CNP

2', 3' cyclic nucleotide 3' phosphohydrolase , 2',3'-cyclic-nucleotide 3'-phosphodiesterase , CNPase , cyclic nucleotide phosphodiesterase 1 , CNP2 , 2',3'-cyclic nucleotide 3' phosphodiesterase , cyclic-CMP phosphodiesterase , 2', 3'-cyclic nucleotide phosphodiesterase , C-type natriuretic peptide , natriuretic peptide precursor C , natriuretic peptide precursor type C , 2',3'-cyclic-nucleotide 3'-phosphodiesterase-like , C-type natriuretic peptide 3 , CNP

GENE ID SPECIES
1267 Homo sapiens
12799 Mus musculus
25275 Rattus norvegicus
280752 Bos taurus
395921 Gallus gallus
454673 Pan troglodytes
607694 Canis lupus familiaris
641337 Macaca mulatta
100171506 Pongo abelii
18159 Mus musculus
493773 Ovis aries
325896 Danio rerio
100467749 Ailuropoda melanoleuca
100595130 Nomascus leucogenys
419487 Gallus gallus
101120423 Ovis aries
444056 Xenopus laevis
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