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May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.. Additionally we are shipping OAS1A Proteins (6) and OAS1A Antibodies (5) and many more products for this protein.
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Thus, activation of RNase L (show RNASEL ELISA Kits) does not require mouse hepatitis virus virus-induced interferon (show IFNA ELISA Kits) but rather correlates with adequate levels of basal Oas (show SMOC1 ELISA Kits) gene expression, maintained by basal interferon (show IFNA ELISA Kits) signaling.
Mouse hepatitis virus Ns2 cleaves 2',5'-oligoadenylate, the product of 2',5'-oligoadenylate synthetase, to prevent activation of the cellular endoribonuclease RNase L (show RNASEL ELISA Kits) and consequently block viral RNA degradation.
Activation of Oas1a gene expression by type I IFN requires both STAT1 (show STAT1 ELISA Kits) and STAT2 (show STAT2 ELISA Kits)
In the absence of a functional OAS1a pathway, herpes simplex virus type 1 antigen expression is more widespread, and the ability of IFN-beta (show IFNB1 ELISA Kits) transgene treatment to reduce infectious HSV-1 in eyes and trigeminal ganglia is lost.
May play a role in mediating resistance to virus infection, control of cell growth, differentiation, and apoptosis.
(2-5')oligo(A) synthase 1A
, (2-5')oligo(A) synthetase 1A
, 2'-5'-oligoadenylate synthase 1A
, 2-5A synthase 1A
, 2-5A synthetase 1A
, p42 OAS