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OAS3 encodes an enzyme included in the 2', 5' oligoadenylate synthase family. Additionally we are shipping OAS3 Kits (7) and and many more products for this protein.
Showing 10 out of 56 products:
Human Polyclonal OAS3 Primary Antibody for WB - ABIN390166
Ito, Shichijo, Tsuda, Ochi, Harashima, Saito, Itoh: Molecular basis of T cell-mediated recognition of pancreatic cancer cells. in Cancer research 2001
Show all 4 references for ABIN390166
Human Polyclonal OAS3 Primary Antibody for EIA, WB - ABIN358718
Rebouillat, Hovnanian, David, Hovanessian, Williams: Characterization of the gene encoding the 100-kDa form of human 2',5' oligoadenylate synthetase. in Genomics 2001
Show all 3 references for ABIN358718
Here we report, to our knowledge, the first analysis of nuclear signal import in the pseudo enzymatic domain DI of human OAS3
OAS3 displayed a higher affinity for dsRNA in intact cells than either OAS1 (show OAS1 Antibodies) or OAS2 (show OAS2 Antibodies), consistent with its dominant role in RNase L (show RNASEL Antibodies) activation.
Preliminary study suggests that OAS (show SMOC1 Antibodies) gene cluster and CD209 (show CD209 Antibodies) gene polymorphisms influence the risk of developing clinical symptoms in Chikungunya virus-infected patients.
Common variation at 12q24.13 (OAS3 intron) influences chronic lymphocytic leukemia risk.
The combined high affinity for double-stranded RNA and the capability to produce 2'-5'-linked oligoadenylates of sufficient length to activate RNase L (show RNASEL Antibodies) suggests that OAS3 is a potent activator of RNase L (show RNASEL Antibodies).
The results suggest that OAS1 (show OAS1 Antibodies)-OAS3-OAS2 (show OAS2 Antibodies) haplotypes are associated with differential susceptibility to clinical outcomes of dengue infection.
among the members of the OAS (show SMOC1 Antibodies) family, OAS1 (show OAS1 Antibodies) p46 (show POLDIP3 Antibodies) and OAS3 p100 mediate the RNase L (show RNASEL Antibodies)-dependent antiviral activity against HCV
The data suggest a possible association between OAS2 (show OAS2 Antibodies) and OAS3 single nucleotide polymorphisms and the outcome of tick-borne encephalitis virus infection in a Russian population.
OAS (show SMOC1 Antibodies) are interferon (show IFNA Antibodies)-inducible enzymes catalyzing 2'-5' instead of 3'-5' phosphodiester bond formation [review]
This gene encodes an enzyme included in the 2', 5' oligoadenylate synthase family. This enzyme is induced by interferons and catalyzes the 2', 5' oligomers of adenosine in order to bind and activate RNase L. This enzyme family plays a significant role in the inhibition of cellular protein synthesis and viral infection resistance.
2'-5'oligoadenylate synthetase 3
, 2'-5' oligoadenylate synthetase 3
, 2'-5'-oligoadenylate synthase 3
, (2-5')oligo(A) synthase 3
, 2'-5'-oligoadenylate synthetase 3
, 2-5A synthase 3
, 2',5'-oligoadenylate synthetase-like 10
, 2'-5' oligoadenylate synthetase-like 10
, (2-5')oligo(A) synthetase 3
, 2'-5'oligoadenylate synthetase p100
, 2-5A synthetase 3
, p100 OAS