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Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.. Additionally we are shipping OASL Proteins (6) and OASL Kits (4) and many more products for this protein.
Showing 10 out of 40 products:
Human Polyclonal OASL Primary Antibody for IHC (p), WB - ABIN390168
Hovnanian, Rebouillat, Levy, Mattei, Hovanessian: The human 2',5'-oligoadenylate synthetase-like gene (OASL) encoding the interferon-induced 56-kDa protein maps to chromosome 12q24.2 in the proximity of the 2',5'-OAS locus. in Genomics 1999
Show all 7 Pubmed References
Human Polyclonal OASL Primary Antibody for IHC, IHC (p) - ABIN4341265
Tanaka, Nishida, Aida, Maruyama, Shimada, Suzuki, Shimura, Takizawa, Takahashi, Akiyama, Arai-Yamashita, Furuya, Kawaguchi, Kaneshige, Katoh, Endo, Kobayashi: Enterovirus infection, CXC chemokine ligand 10 (CXCL10), and CXCR3 circuit: a mechanism of accelerated beta-cell failure in fulminant type 1 diabetes. in Diabetes 2009
These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.
OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth.
Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 (show OAS2 Antibodies) genes.
these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I (show DDX58 Antibodies) activation.
we propose that VSV treatment combined with the selective regulation of genes such as STAT1 (show STAT1 Antibodies) and OASL2 will improve therapeutic outcomes for CUG2 (show CENPW Antibodies)-overexpressing tumors
variants in LPL (show LCP1 Antibodies), OASL and TOMM40 (show TOMM40 Antibodies)/APOE (show APOE Antibodies)-C1-C2-C4 genes are associated with multiple cardiovascular-related traits
The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein.
The expression of OASL and IFIT2 (show IFIT2 Antibodies) was significantly higher in SLE patients than in controls.
OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains.
interaction with methyl CpG-binding protein 1 (show MBD1 Antibodies) was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL
Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.
, 59 kDa 2'-5'-oligoadenylate synthetase-like protein-like
, 59 kDa 2'-5'-oligoadenylate synthase-like protein-like
, 2'-5'-OAS-related protein
, 2'-5'-oligoadenylate synthase-like protein
, 59 kDa 2'-5'-oligoadenylate synthase-like protein
, 59 kDa 2'-5'-oligoadenylate synthetase-like protein
, TR-interacting protein 14
, thyroid receptor-interacting protein 14