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Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.. Additionally we are shipping OASL Antibodies (40) and OASL Proteins (6) and many more products for this protein.
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These data uncover a promycobacterial role for STING-dependent OASL production during Mycobacterium leprae infection that directs the host immune response toward a niche that permits survival of the pathogen.
OASL acts as a cellular antiviral protein and RSV NS1 suppresses this function to evade cellular innate immunity and allow virus growth.
Primary mononuclear cells from patients with systemic sclerosis have increased basal levels of OASL and OAS2 (show OAS2 ELISA Kits) genes.
these findings show a mechanism by which human OASL contributes to host antiviral responses by enhancing RIG-I (show DDX58 ELISA Kits) activation.
we propose that VSV treatment combined with the selective regulation of genes such as STAT1 (show STAT1 ELISA Kits) and OASL2 will improve therapeutic outcomes for CUG2 (show CENPW ELISA Kits)-overexpressing tumors
variants in LPL (show LCP1 ELISA Kits), OASL and TOMM40 (show TOMM40 ELISA Kits)/APOE (show APOE ELISA Kits)-C1-C2-C4 genes are associated with multiple cardiovascular-related traits
The pronounced difference in gene regulation between the OASL gene agrees with a functional difference between these genes, which must exist as a consequence of the lack of the 2-5A synthetase activity of the OASL protein.
The expression of OASL and IFIT2 was significantly higher in SLE patients than in controls.
OASLa, a major isoform of OASL induced in human liver, may mediate anti-HCV activity through two different domains.
interaction with methyl CpG-binding protein 1 (show MBD1 ELISA Kits) was confirmed in vitro and in vivo and was mapped to the ubiquitin-like domain of p59 OASL
Does not have 2'-5'-OAS activity, but binds double- stranded RNA and DNA.
, 59 kDa 2'-5'-oligoadenylate synthetase-like protein-like
, 59 kDa 2'-5'-oligoadenylate synthase-like protein-like
, 2'-5'-OAS-related protein
, 2'-5'-oligoadenylate synthase-like protein
, 59 kDa 2'-5'-oligoadenylate synthase-like protein
, 59 kDa 2'-5'-oligoadenylate synthetase-like protein
, TR-interacting protein 14
, thyroid receptor-interacting protein 14