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anti-4-Aminobutyrate Aminotransferase (ABAT) Antibodies

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. Additionally we are shipping ABAT Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABAT 18 P80404
ABAT 268860 P61922
ABAT 81632 P50554
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Top anti-ABAT Antibodies at antibodies-online.com

Showing 10 out of 68 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ABAT Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Transfected 293T 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-ABAT Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:12500Positive Control: Human Placenta Host: Rabbit  Target Name: ABAT  Sample Tissue: Human Fetal Muscle  Antibody Dilution: 1.0 µg/mL 100 μL Log in to see 2 to 3 Days
$289.00
Details
Xenopus laevis Rabbit Un-conjugated WB Hum. Fetal Muscle; Host:Rabbit. Target Name:ABAT. Sample Tissue:Human Fetal Muscle. Antibody Dilution: 1.0ug/ml.; ABAT antibody - middle region in Hum. Fetal Muscle cells using Western Blot Human Placenta; WB Suggested Anti-ABAT Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:12500. Positive Control: Human Placenta; ABAT antibody - middle region in Human Placenta cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated WB Western Blot analysis of ABAT expression in transfected 293T cell line by ABAT MaxPab polyclonal antibody.Lane 1: ABAT transfected lysate(55 KDa).Lane 2: Non-transfected lysate. ABAT MaxPab polyclonal antibody. Western Blot analysis of ABAT expression in human liver. 50 μg Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Antigen: 0.2 µg/100 µL  Primary: Antiserum, 1:500, 1:1000, 1:2000, 1:4000, 1:8000, 1:16000, 1:32000;  Secondary: HRP conjugated Goat-Anti-Rabbit IgG at 1: 5000;  TMB staining;  Read the data in MicroplateReader by 450 Formalin-fixed and paraffin embedded rat brain labeled with Anti-ABAT Polyclonal Antibody, Unconjugated (ABIN705641) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB WB Image ABAT antibody detects ABAT protein by Western blot analysis. A. 30 µg HepG2 whole cell lysate/extract 7.5 % SDS-PAGE ABAT antibody , dilution: 1:1000 WB Image Sample (50 ug of whole cell lysate) A: Mouse brain 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB IHC-P Image ABAT antibody detects ABAT protein at mitochondria on mouse kidney by immunohistochemical analysis. Sample: Paraffin-embedded mouse kidney. ABAT antibody , dilution: 1:500. IHC-P Image ABAT antibody detects ABAT protein at mitochondria on mouse liver by immunohistochemical analysis. Sample: Paraffin-embedded mouse liver. ABAT antibody , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated IHC, WB 100 μL Log in to see 14 Days
$369.79
Details

ABAT Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABAT Antibodies

  1. Cow (Bovine) Polyclonal ABAT Primary Antibody for WB - ABIN2784614 : Inada, Koga, Ishiguro, Horiuchi, Syu, Yoshio, Takahashi, Ozaki, Arinami: Pathway-based association analysis of genome-wide screening data suggest that genes associated with the gamma-aminobutyric acid receptor signaling pathway are involved in neuroleptic-induced, treatment-resistant tardive dyskinesia. in Pharmacogenetics and genomics 2008 (PubMed)

  2. Human Polyclonal ABAT Primary Antibody for WB - ABIN513032 : Perdomo, Ciccosanti, Iacono, Angeletti, Corazzari, Daniele, Testa, Pisa, Ippolito, Antonucci, Fimia, Piacentini: Liver protein profiling in chronic hepatitis C: identification of potential predictive markers for interferon therapy outcome. in Journal of proteome research 2012 (PubMed)

More Antibodies against ABAT Interaction Partners

Human 4-Aminobutyrate Aminotransferase (ABAT) interaction partners

  1. This study utilized ER+ IBC to identify a metagene including ABAT and STC2 (show STC2 Antibodies) as predictive biomarkers for endocrine therapy resistance.

  2. A-to-G transition at nucleotide 754 of the human ABAT gene identified in lymphoblast cDNA (c.754A>G) results in substitution of an invariant arginine at amino acid 220 by lysine (p.Arg220Lys). This point mutation results in destabilization of the binding of pyridoxal-5'-phosphate to GABA-transaminase (required for transamination of GABA to succinic semialdehyde) and thus results in GABA-transaminase deficiency.

  3. Findings point to a possible role of ABAT gene-regulated GABA catabolism for an altered processing of somatosensory stimuli as a potential vulnerability marker for affective disorders.

  4. direct involvement of ABAT in pathways affecting lower esophageal sphincter (LES (show FUT3 Antibodies)) control in gastro esophageal reflux disease

  5. excessive prenatal GABA exposure in the central nervous system (CNS) is responsible for the clinical manifestations of GABA transaminase deficiency [case report]

  6. Marked differences in platelet uptake of GABA and activity of catabolic enzyme GABA-T between patients with generalized and localization-related epileptic syndromes. May indicate an impairment in function of brain GABAergic systems.

  7. results suggest that the Cys321 residue is essential for the catalytic function of GABAT, and that it is involved in the formation of a disulfide link between two monomers of human brain GABAT

  8. lysine 357 is essential for catalytic function of brain GABA transaminase, and is involved in binding PLP (show PLP1 Antibodies) at the active site

  9. Analysis of the autistic disorder susceptibility locus suggests an association on chromosome 16p between GRIN2A (show GRIN2A Antibodies) and ABAT.

ABAT Antigen Profile

Protein Summary

4-aminobutyrate aminotransferase (ABAT) is responsible for catabolism of gamma-aminobutyric acid (GABA), an important, mostly inhibitory neurotransmitter in the central nervous system, into succinic semialdehyde. The active enzyme is a homodimer of 50-kD subunits complexed to pyridoxal-5-phosphate. The protein sequence is over 95% similar to the pig protein. GABA is estimated to be present in nearly one-third of human synapses. ABAT in liver and brain is controlled by 2 codominant alleles with a frequency in a Caucasian population of 0.56 and 0.44. The ABAT deficiency phenotype includes psychomotor retardation, hypotonia, hyperreflexia, lethargy, refractory seizures, and EEG abnormalities. Multiple alternatively spliced transcript variants encoding the same protein isoform have been found for this gene.

Gene names and symbols associated with ABAT

  • 4-aminobutyrate aminotransferase (ABAT) antibody
  • 4-aminobutyrate aminotransferase (abat) antibody
  • 4-aminobutyrate aminotransferase (gabT) antibody
  • 4-aminobutyrate aminotransferase (gabT-1) antibody
  • 4-aminobutyrate aminotransferase (gabT-2) antibody
  • 4-aminobutyrate aminotransferase (gabT-3) antibody
  • 4-aminobutyrate aminotransferase (CNE01830) antibody
  • 4-aminobutyrate aminotransferase (Mmwyl1_0047) antibody
  • 4-aminobutyrate aminotransferase, mitochondrial (CpipJ_CPIJ008729) antibody
  • 4-aminobutyrate aminotransferase (Kcr_0880) antibody
  • 4-aminobutyrate aminotransferase (Bcenmc03_4909) antibody
  • 4-aminobutyrate aminotransferase (Hden_0972) antibody
  • 4-aminobutyrate aminotransferase (Dbac_2000) antibody
  • 4-aminobutyrate aminotransferase (Mesil_2400) antibody
  • 4-aminobutyrate aminotransferase (Trad_0121) antibody
  • 4-aminobutyrate aminotransferase (Abat) antibody
  • 9630038C02Rik antibody
  • AI255750 antibody
  • BA0325 antibody
  • beta-AlaAT antibody
  • cb880 antibody
  • ENSMUSG00000051226 antibody
  • fj82a01 antibody
  • GABA-AT antibody
  • GABA-T antibody
  • Gabaat antibody
  • Gabat antibody
  • Gm9851 antibody
  • I54 antibody
  • L-AIBAT antibody
  • Laibat antibody
  • NPD009 antibody
  • PSPTO0259 antibody
  • PSPTO0301 antibody
  • PSPTO1890 antibody
  • wu:fj82a01 antibody
  • X61497 antibody

Protein level used designations for ABAT

4-aminobutyrate aminotransferase, mitochondrial , GABA-T , 4-aminobutyrate aminotransferase , (S)-3-amino-2-methylpropionate transaminase , 4-aminobutyrate transaminase , GABA aminotransferase , GABA transaminase , GABA transferase , gamma-amino-N-butyrate transaminase , GABA-AT , L-AIBAT , beta-alanine oxoglutarate aminotransferase

GENE ID SPECIES
100051470 Equus caballus
378968 Danio rerio
416642 Gallus gallus
453903 Pan troglodytes
1086502 Bacillus anthracis str. Ames
1169096 Shewanella oneidensis MR-1
1181867 Pseudomonas syringae pv. tomato str. DC3000
1181910 Pseudomonas syringae pv. tomato str. DC3000
1183535 Pseudomonas syringae pv. tomato str. DC3000
3196857 Ruegeria pomeroyi DSS-3
3257776 Cryptococcus neoformans var. neoformans JEC21
5367528 Marinomonas sp. MWYL1
6041096 Culex quinquefasciatus
6094157 Candidatus Korarchaeum cryptofilum OPF8
6127721 Burkholderia cenocepacia MC0-3
9386856 Hyphomicrobium denitrificans ATCC 51888
100174312 Pongo abelii
1064855 Tropheryma whipplei TW08/27
8377675 Desulfomicrobium baculatum DSM 4028
9251916 Meiothermus silvanus DSM 9946
9279090 Truepera radiovictrix DSM 17093
398751 Xenopus laevis
18 Homo sapiens
397500 Sus scrofa
280969 Bos taurus
268860 Mus musculus
81632 Rattus norvegicus
479856 Canis lupus familiaris
Selected quality suppliers for anti-ABAT (ABAT) Antibodies
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