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anti-5'-3' Exoribonuclease 1 (XRN1) Antibodies

SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. Additionally we are shipping XRN1 Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
XRN1 54464 Q8IZH2
XRN1 24127 P97789
XRN1 300944  
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Top anti-XRN1 Antibodies at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated WB WB Suggested Anti-XRN1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: MCF7 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IP, PLA, WB Detection of Human XRN1 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate (5, 15 and 15 ug for WB, 1 mg for IP) from HeLa cells. Antibodies: Affinity purified rabbit anti-XRN1 antibody ABIN153005 used at 0.1 ug/ml for Western Blot and at 3 ug/mg lysate for IP. XRN1 that was immunoprecipitated by ABIN153005 was also blotted with a different affinity purified antibody (1 ug/ml) to an upstream region of XRN1. Immunoprecipitation reactions were controlled using normal rabbit IgG (Ctrl IP). Detection: Chemiluminescence with an exposure time of 10 seconds. 100 μL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB XRN1 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IP, WB   100 μL Log in to see 8 to 10 Days
$815.83
Details
Human Rabbit Un-conjugated IP, PLA, WB   100 μL Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated WB Western Blot analysis of XRN1 expression in transfected 293T cell line by XRN1 MaxPab polyclonal antibody.Lane 1: XRN1 transfected lysate(53.80 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated WB   80 μL Log in to see 8 to 10 Days
$317.17
Details
Human Rabbit Un-conjugated WB   0.4 mL Log in to see 2 to 3 Days
$391.88
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p)   0.1 mL Log in to see 8 to 11 Days
$439.69
Details

XRN1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human ,


Mouse (Murine)


Rat (Rattus)


Top referenced anti-XRN1 Antibodies

  1. Human Polyclonal XRN1 Primary Antibody for IP, PLA - ABIN153005 : Ozgur, Chekulaeva, Stoecklin: Human Pat1b connects deadenylation with mRNA decapping and controls the assembly of processing bodies. in Molecular and cellular biology 2010 (PubMed)
    Show all 6 references for ABIN153005

  2. Cow (Bovine) Polyclonal XRN1 Primary Antibody for WB - ABIN2779146 : Olsen, Blagoev, Gnad, Macek, Kumar, Mortensen, Mann: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks. in Cell 2006 (PubMed)

More Antibodies against XRN1 Interaction Partners

Human 5'-3' Exoribonuclease 1 (XRN1) interaction partners

  1. Data show that the AR-miR (show MLXIP Antibodies)-204-XRN1-miR (show MLXIP Antibodies)-34a positive feedback loop and a dual function of miR (show MLXIP Antibodies)-204/XRN1 axis in prostate cancer.

  2. Thus, Xrn1 is a cellular factor regulating dsRNA accumulation and dsRNA-responsive innate immune effectors.

  3. Occupation of each miR (show MLXIP Antibodies)-122 binding site on 5' untranslated region of the hepatitis C virus genome contributes equally and cooperatively to virus replication via protecting from Xrn1 exoribonuclease degradation.

  4. Authors conclude that Xrn1 is the dominant 5' exoribonuclease mediating decay of hepatitis C virus RNA and that miR (show MLXIP Antibodies)-122 provides protection against it

  5. Mouse Xrn1 plays a role in RNA turnover.

  6. Data show that 5' exonuclease (show EXO1 Antibodies) Xrn1 knockdown and miR (show MLXIP Antibodies)-122 supplementation have equal, redundant, and nonadditive effects on the rate of viral RNA decay, indicating that miR (show MLXIP Antibodies)-122 protects HCV RNA from 5' decay.

  7. findings reveal a role for XRN1 in decapping and provide a molecular basis for the coupling of decapping to 5'-->3' mRNA degrada

  8. LSm1 (show LSM1 Antibodies)-7 proteins colocalize with DCP1 (show ACE Antibodies),DCP2 (show DCP2 Antibodies) and Xrn1 in cytoplasmic foci

Mouse (Murine) 5'-3' Exoribonuclease 1 (XRN1) interaction partners

  1. XRN1 knockdown impairs the translational repression triggered by NMDA. Collectively, these observations support a role for the SX-bodies in the reversible masking and silencing of mRNAs at the synapse.

XRN1 Antigen Profile

Protein Summary

SEP1 localizes to cytoplasmic foci containing a complex of mRNA-degrading enzymes. In addition to mRNA metabolism, yeast Sep1 has been implicated in a variety of nuclear and cytoplasmic functions, including homologous recombination, meiosis, telomere maintenance, and microtubule assembly.

Gene names and symbols associated with XRN1

  • 5'-3' exoribonuclease 1 (xrn1) antibody
  • 5'-3' exoribonuclease 1 (XRN1) antibody
  • 5'-3' exoribonuclease 1 (Tsp_05930) antibody
  • 5'-3' exoribonuclease 1 (LOC100351589) antibody
  • 5'-3' exoribonuclease 1 (Xrn1) antibody
  • Dhm2 antibody
  • exo antibody
  • mXrn1 antibody
  • RGD1309713 antibody
  • SEP1 antibody
  • wu:fk92c07 antibody
  • zgc:63635 antibody

Protein level used designations for XRN1

5'-3' exoribonuclease 1 , strand-exchange protein 1 homolog , protein Dhm2

GENE ID SPECIES
394008 Danio rerio
424778 Gallus gallus
460744 Pan troglodytes
10911092 Trichinella spiralis
100351589 Oryctolagus cuniculus
54464 Homo sapiens
24127 Mus musculus
300944 Rattus norvegicus
477100 Canis lupus familiaris
540834 Bos taurus
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