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anti-5'-3' Exoribonuclease 2 (XRN2) Antibodies

XRN2 shares similarity with the mouse Dhm1 and the yeast dhp1 gene. Additionally we are shipping XRN2 Kits (3) and XRN2 Proteins (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
XRN2 22803 Q9H0D6
XRN2 24128 Q9DBR1
Anti-Rat XRN2 XRN2 362229  
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Top anti-XRN2 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB XRN2 Antibody (N-term) (ABIN658280) western blot analysis in T47D cell line lysates (35 µg/lane). This demonstrates the XRN2 antibody detected the XRN2 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC, IHC (p), IP, WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252879] - Detection of Human XRN2 by Western Blot and Immunoprecipitation. Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded) and 293T (T, 50 mcg) cells. Antibodies: Affinity purified rabbit anti- XRN2 antibody ABIN252879 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B) and used for IP at 3 mcg/mg lysate. XRN2 was also immunoprecipitated by another rabbit anti-XRN2 antibody, which recognizes an upstream epitope. Detection: Chemiluminescence with exposure times of 3 seconds (A) and 10 seconds (B). 0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Un-conjugated WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252877] - Detection of Human and Mouse XRN2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody ABIN252877 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B). XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibodies  and ABIN252879, which recognize downstream epitopes. Detection: Chemiluminescence with exposure times of 3 minutes (A) and 10 seconds (B). 0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Un-conjugated ELISA, IHC, WB 100 μL Log in to see 14 Days
$201.19
Details
Human Rabbit Un-conjugated WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated WB Western Blot and Immunoprecipitation: XRN2 Antibody [ABIN252878] - Detection of Human and Mouse XRN2 by Western Blot (h&m) and Immunoprecipitation (h). Samples: Whole cell lysate from HeLa (5, 15 and 50 mcg for WB, 1 mg for IP, 20% of IP loaded), 293T (T, 50 mcg) and mouse NIH3T3 (M, 50 mcg) cells. Antibodies: Affinity purified rabbit anti-XRN2 antibody ABIN252878 used for WB at 0.04 mcg/ml (A) and 1 mcg/ml (B). XRN2 was immunoprecipitated by another rabbit anti-XRN2 antibody and ABIN252879, which recognize downstream epitopes.  Detection: Chemiluminescence with exposure times of 10 seconds (A) and 3 seconds (B). 0.1 mL Log in to see 5 to 7 Days
$477.75
Details
Chicken Rabbit Un-conjugated IHC, WB   200 μL Log in to see 9 Days
$487.50
Details
Human Rabbit Un-conjugated ELISA   200 μL Log in to see 8 to 10 Days
$713.17
Details

XRN2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human , ,


, , , , ,
Mouse (Murine)


Top referenced anti-XRN2 Antibodies

  1. Human Polyclonal XRN2 Primary Antibody for WB - ABIN658280 : Lu, Liu, James, Vikis, Liu, Wen, Franklin, You: Genetic variants cis-regulating Xrn2 expression contribute to the risk of spontaneous lung tumor. in Oncogene 2010 (PubMed)

More Antibodies against XRN2 Interaction Partners

Human 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. Chromatin immunoprecipitation experiments further show that IL-1 (show IL1A Antibodies) stimulation leads to decrease in NKRF (show NKRF Antibodies) aa 421-429 phosphorylation and dissociation of NELF-E (show RDBP Antibodies) and XRN2 by concomitant resumption of transcription elongation of a synthetic reporter

  2. P-TEFb (show CCNT1 Antibodies) regulates termination by promoting chromatin recruitment and activation of a cotranscriptional RNA processing enzyme, Xrn2.

  3. The results suggest that CARF (show CDKN2AIP Antibodies) regulates early steps of pre-rRNA processing during ribosome biogenesis by controlling spatial distribution of XRN2 between the nucleoplasm and nucleolus.

  4. Kinetic competition between elongating pol II and the Xrn2 exonuclease (show EXO1 Antibodies) is integral to termination of transcription on most human genes.

  5. found that the 3' fragments of target pre-mRNA generated by ASO were almost completely degraded from their 5' ends by nuclear XRN2 after RNase H1 (show RNASEH1 Antibodies)-mediated cleavage

  6. The restriction of JFH1 and H77D hepatitis C virus replication by Xrn2 is likely indirect in nature and possibly linked to cytopathic effects of these robustly replicating viruses.

  7. Xrn2 has a cytoplasmic, antiviral function against HCV that is counteracted by HCV's subversion of miR (show MLXIP Antibodies)-122 to form a protective oligomeric complex at the 5' end of the viral genome.

  8. Mammalian target of rapamycin (show FRAP1 Antibodies) protein regulates the diffusion of Xrn2 from the nucleolus to the nucleoplasm under heat stress conditions.

  9. hnRNPK (show HNRNPK Antibodies) may play a role in recruitment of XRN2 to gene loci thus regulating coupling 3'-end pre-mRNA processing (show PRPF39 Antibodies) to transcription termination.

  10. Microprocessor orchestrates the recruitment of termination factors Setx (show SETX Antibodies) and Xrn2, and the 3'-5' exoribonuclease, Rrp6 (show EXOSC10 Antibodies), to initiate RNAPII pausing and premature termination at the HIV-1 promoter through cleavage of the stem-loop RNA, TAR (show RBM8A Antibodies).

Mouse (Murine) 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. Genetic variants regulating Xrn2 expression in cis (show CISH Antibodies) are determinants of spontaneous lung tumor susceptibility in mice and have genetic equivalents in lung cancer susceptibility in human beings.

Arabidopsis thaliana 5'-3' Exoribonuclease 2 (XRN2) interaction partners

  1. AtXRN2 has a role in ribosomal RNA processing.

  2. The nuclear exoribonucleases XRN2 and XRN3 the nucleotidase/phosphatase FIERY1 (show SAL1 Antibodies) are endogenous posttranscriptional gene silencing suppressors.

XRN2 Antigen Profile

Protein Summary

This gene shares similarity with the mouse Dhm1 and the yeast dhp1 gene. The yeast gene is involved in homologous recombination and RNA metabolism, such as RNA synthesis and RNA trafficking. Complementation studies show that Dhm1 has a similar function in mouse as dhp1. The function of the human gene has not yet been determined. Transcript variants encoding different isoforms have been noted for this gene\; however, their full-length nature is not known.

Gene names and symbols associated with XRN2

  • 5'-3' exoribonuclease 2 (xrn2) antibody
  • 5'-3' exoribonuclease 2 (XRN2) antibody
  • 5'-3' exoribonuclease 2 (TA11675) antibody
  • 5'-3' exoribonuclease 2 (LELG_04162) antibody
  • 5'-3' exoribonuclease 2 (AOR_1_874194) antibody
  • 5'-3' exoribonuclease 2 (PTRG_01514) antibody
  • 5'-3' exoribonuclease 2 (PTRG_10866) antibody
  • 5'-3' exoribonuclease 2 (Tsp_08094) antibody
  • 5'-3' exoribonuclease 2 (LOC100353161) antibody
  • 5'-3' exoribonuclease 2 (Xrn2) antibody
  • AO090012000503 antibody
  • AtXRN2 antibody
  • DKFZp459J063 antibody
  • exoribonuclease 2 antibody
  • K16E1.2 antibody
  • K16E1_2 antibody
  • wu:fb38g12 antibody
  • wu:fj53d06 antibody
  • zgc:55717 antibody

Protein level used designations for XRN2

5'-3' exoribonuclease 2 , 5'-3' exoribonuclease 2-like , DHP protein , Dhm1-like protein (mouse homolog) , protein Dhm1

GENE ID SPECIES
321940 Danio rerio
458131 Pan troglodytes
477133 Canis lupus familiaris
517417 Bos taurus
700934 Macaca mulatta
733834 Xenopus (Silurana) tropicalis
3861687 Theileria annulata strain Ankara
5231754 Lodderomyces elongisporus NRRL YB-4239
5987983 Aspergillus oryzae RIB40
6338441 Pyrenophora tritici-repentis Pt-1C-BFP
6349178 Pyrenophora tritici-repentis Pt-1C-BFP
10906655 Trichinella spiralis
100031372 Monodelphis domestica
100049102 Xenopus laevis
100050094 Equus caballus
100173960 Pongo abelii
100353161 Oryctolagus cuniculus
100388181 Callithrix jacchus
100468930 Ailuropoda melanoleuca
100517201 Sus scrofa
100593111 Nomascus leucogenys
22803 Homo sapiens
24128 Mus musculus
362229 Rattus norvegicus
421236 Gallus gallus
834261 Arabidopsis thaliana
Selected quality suppliers for anti-XRN2 (XRN2) Antibodies
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