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5'-Nucleotidase, Ecto (CD73) Proteins (NT5E)

NT5E encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. Additionally we are shipping CD73 Antibodies (230) and CD73 Kits (43) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
NT5E 23959 Q61503
NT5E 58813  
NT5E 4907 P21589
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Top CD73 Proteins at antibodies-online.com

Showing 10 out of 14 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Human Cells Mouse His tag 10 μg Log in to see 16 Days
$250.80
Details
HOST_Human Cells Rat His tag 50 μg Log in to see 16 Days
$547.80
Details
HOST_Human Cells Human His tag 100 μg Log in to see 16 Days
$1,009.80
Details
HOST_Human Cells Cynomolgus His tag 50 μg Log in to see 16 Days
$547.80
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Human GST tag 50 μg Log in to see 9 to 11 Days
$242.00
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_Human Mouse His tag   10 μg Log in to see 5 Days
$203.50
Details
HOST_HEK293 Human His tag   50 μg Log in to see 5 Days
$522.50
Details

NT5E Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) , ,

Rat (Rattus)

Human , , , ,
,

Top referenced CD73 Proteins

  1. Mouse (Murine) CD73 Protein expressed in Human Cells - ABIN2007543 : Louis, Robinson, MacManus, Karhausen, Scully, Colgan: Control of IFN-alphaA by CD73: implications for mucosal inflammation. in Journal of immunology (Baltimore, Md. : 1950) 2008 (PubMed)
    Show all 2 references for ABIN2007543

  2. Human CD73 Protein expressed in Human Cells - ABIN3216390 : Grünewald, Ridley: CD73 represses pro-inflammatory responses in human endothelial cells. in Journal of inflammation (London, England) 2010 (PubMed)
    Show all 2 references for ABIN3216390

More Proteins for 5'-Nucleotidase, Ecto (CD73) (NT5E) Interaction Partners

Zebrafish 5'-Nucleotidase, Ecto (CD73) (NT5E) interaction partners

  1. enzymatic properties of an ecto-5'-nucleotidase (show ACPP Proteins) activity in brain membranes of zebrafish

Pig (Porcine) 5'-Nucleotidase, Ecto (CD73) (NT5E) interaction partners

  1. CD39 (show ENTPD1 Proteins) and CD73 and their enzymatic activities that convert extracellular nucleotides are highly expressed and could have special function in the valve

Mouse (Murine) 5'-Nucleotidase, Ecto (CD73) (NT5E) interaction partners

  1. These data reveal a novel function of CD73 ectonucleotidase in arresting CD8 (show CD8A Proteins)(+) T-cell differentiation and support the idea that CD73-driven adenosine production by Tc17 cells may promote stem cell-like properties in Tc17 cells.

  2. The ecto-5'-nucleotidase (show ACPP Proteins) derived extracellular formation of adenosine does not contribute substantially to adenosine's well known cardioprotective effect in early phase ischemic preconditioning.

  3. Expression of NPP1 (show ENPP1 Proteins) and 5'-nucleotidase (show ACPP Proteins) by valve interstitial cells promotes the mineralization of the aortic valve through A2aR (show ADORA2A Proteins) and a cAMP/PKA/CREB (show CREB1 Proteins) pathway.

  4. CD73 is dispensable for normal CD8 (show CD8A Proteins)+ T-cell differentiation and function

  5. The mouse model deficient in CD73, with other targeted mutant mice with vascular mi (show ADIPOQ Proteins)neralization, attests to the presence of a complex pro-mineralization/anti-mineralization network that prevents ectopic tissue mineralization.

  6. In the urothelium of animals with bladder cancer there was an increase in the expression of ecto-5'-nucleotidase (show ACPP Proteins).

  7. Tetraspanin CD9 (show CD9 Proteins) and ectonucleotidase CD73 identify an osteochondroprogenitor population with elevated osteogenic properties.

Human 5'-Nucleotidase, Ecto (CD73) (NT5E) interaction partners

  1. CD73 promotes the growth of human colorectal cancer cells through EGFR (show EGFR Proteins) and the b-catenin/cyclin D1 (show CCND1 Proteins) signaling pathway. CD73 may be used as a valuable biomarker of colorectal cancer.

  2. The NT5E gene is involved in both intrinsic and acquired resistance to platinum-based drugs in ovarian cancer. [meta-analysis]

  3. report on a Chinese family with CALJA and novel compound heterozygous mutations (c.1360G>A (p.Gly454Arg) and c.1387C>T (p.Arg463X)) in NT5E

  4. Prostatic acid phosphatase (show ACPP Proteins) delays prostate cancer cell growth in G1 phase of the cell cycle.

  5. role of CD73 and CD39 (show ENTPD1 Proteins) ectonucleotidases in T cell differentiation

  6. Expression of NPP1 (show ENPP1 Proteins) and 5'-nucleotidase by valve interstitial cells promotes the mineralization of the aortic valve through A2aR (show ADORA2A Proteins) and a cAMP/PKA/CREB (show CREB1 Proteins) pathway.

  7. Studies suggest that understanding of prostatic acid phosphatase (show ACPP Proteins) function and regulation of expression will have a significant impact on understanding prostate cancer (PCa (show FLVCR1 Proteins)) progression and therapy.

  8. The Nt5e(-/-) targeted mutant mice recapitulate some, but not all, features of ACDC (show ADIPOQ Proteins) and serve as a model system to study pharmacologic interventions for ectopic mineralization.

  9. Certain factors identified within semen, termed semen-derived enhancers of virus infection (SEVI), fragments of prostatic acid phosphatase (show ACPP Proteins), have been shown to significantly enhance HIV-1 infectivity.

CD73 (NT5E) Protein Profile

Protein Summary

This gene encodes an enzyme that catalyzes the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesized under androgen regulation and is secreted by the epithelial cells of the prostate gland. An alternatively spliced transcript variant encoding a longer isoform has been found for this gene. This isoform contains a transmembrane domain and is localized in the plasma membrane-endosomal-lysosomal pathway.

Gene names and symbols associated with NT5E

  • 5'-nucleotidase, ecto (CD73) (nt5e)
  • 5'-nucleotidase, ecto (CD73) (NT5E)
  • 5'-nucleotidase (PSPTO_2277)
  • 5'-nucleotidase (CBU_1233)
  • 5'-nucleotidase (MCA1322)
  • 5 nucleotidase, ecto (LOC100157995)
  • 5' nucleotidase, ecto (Nt5e)
  • 5'-nucleotidase, cytosolic IB (Nt5c1b)
  • acid phosphatase, prostate (ACPP)
  • 5'-NT protein
  • 2210401F01Rik protein
  • 4921514H13Rik protein
  • ACP-3 protein
  • ACP3 protein
  • AI447961 protein
  • AIRP protein
  • CALJA protein
  • CD73 protein
  • CN-IB protein
  • E5NT protein
  • eN protein
  • eNT protein
  • MGC114869 protein
  • NT protein
  • NT5 protein
  • NT5E protein
  • NTE protein
  • PAP protein
  • PSPTO2277 protein
  • zgc:63784 protein

Protein level used designations for NT5E

5'-nucleotidase , 5' nucleotidase, ecto , 5'-nucleotidase, ecto (CD73) , 5'-nucleotidase-like , 5'-NT , ecto-5'-nucleotidase , 5'nucleotidase , autoimmune infertility-related protein , cN1B , cytosolic 5'-nucleotidase 1B , cytosolic 5'-nucleotidase IB , Purine 5-Prime-Nucleotidase , TMPase , prostatic acid phosphatase , prostatic acid phosphotase , thiamine monophosphatase

GENE ID SPECIES
393906 Danio rerio
462864 Pan troglodytes
696509 Macaca mulatta
734513 Xenopus laevis
100070458 Equus caballus
100356979 Oryctolagus cuniculus
100454795 Pongo abelii
100465009 Ailuropoda melanoleuca
100489347 Xenopus (Silurana) tropicalis
1183928 Pseudomonas syringae pv. tomato str. DC3000
1209138 Coxiella burnetii RSA 493
3104879 Methylococcus capsulatus str. Bath
100607892 Nomascus leucogenys
100157995 Sus scrofa
23959 Mus musculus
58813 Rattus norvegicus
70881 Mus musculus
4907 Homo sapiens
474984 Canis lupus familiaris
281363 Bos taurus
421833 Gallus gallus
55 Homo sapiens
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