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G-protein coupled receptor for serotonin\; may have a role in learning and memory [RGD, Feb 2006].. Additionally we are shipping 5-Hydroxytryptamine (Serotonin) Receptor 1B Kits (6) and and many more products for this protein.
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Human Polyclonal HTR1B Primary Antibody for ELISA, WB - ABIN185637
Svenningsson, Chergui, Rachleff, Flajolet, Zhang, El Yacoubi, Vaugeois, Nomikos, Greengard: Alterations in 5-HT1B receptor function by p11 in depression-like states. in Science (New York, N.Y.) 2006
Data suggest that pharmacological stimulation of serotonin 5Ht1b receptor enhances up-regulation of plasma Glp1 (glucagon-like peptide 1 (show GCG Antibodies)) induced by Dpp4 (dipeptidylpeptidase 4 (show DPP4 Antibodies)) inhibition independently of feeding and also improves glucose tolerance.
5-HT1B Knockout and pharmacologic 5-HT1B antagonism both attenuated locomotor hyperactivity in dopamine transporter Knockout mice.
The data of this study showed that while adolescent expression of 5-HT1BRs influences aggressive behavior, a distinct set of 5-HT1B receptors modulates impulsive behavior during adulthood.
The serotoninergic system plays an important role in the regulation of stress-induced depigmentation, which can be mediated by 5-HT1A (show HTR1A Antibodies)/1B receptors.
5-HT(1B)R stimulation increased glutamatergic neurotransmission in the hippocampus in p11KO mice, but not in WT mice. Hippocampal p11 (show S100A10 Antibodies) determines the directionality of 5-HT(1B)R action on emotional memory processing
Selective inhibition of 5-HT2A (show HTR2A Antibodies) by sarpogrelate stimulated angiogenesis, restoring ischemic limb blood perfusion in a severe diabetic mouse model through stimulation of the eNOS (show NOS3 Antibodies)/Akt (show AKT1 Antibodies) pathway via the endothelial 5-HT1B receptor.
Data from double knockout mouse model indicate that deletion of both HTR1A (show HTR1A Antibodies) and HTR1B induces anxiety-like behavioral state associated with increased 5HT (show DDC Antibodies) neurotransmission; mice also exhibit reduced body temperature regulation when exposed to stress.
Data indicate that most p11 (show S100A10 Antibodies) expressing cells in cerebral cortex, hippocampus, cerebellum, & caudate-putamen express HTR1B or co-express HTR1B/HTR4 (show HTR4 Antibodies), suggesting crucial role for p11 (show S100A10 Antibodies) in modulating actions of serotonin via these receptor subtypes.
In the developing barrel field of the neonatal mice 5-HT1B receptors mediate an activity-dependent regulation of the thalamocortical EPSC that could favor the propagation of high-frequency thalamocortical activity
5-Hydroxytryptamine(1B/1D) receptors inhibit capsaicin-induced c-fos immunoreactivity within mouse trigeminal nucleus caudalis.
G-protein coupled receptor for serotonin\; may have a role in learning and memory
, 5-HT1B receptor
, 5-HT<1B> receptor
, 5-hydroxytryptamine receptor 1B
, serotonin receptor 1B
, 5-HT1B serotonin receptor
, 5-hydroxytryptamine (serotonin ) receptor 1B
, serotonin (5-hydroxytryptamine (5HT)) receptor type 1B