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anti-6-Pyruvoyltetrahydropterin Synthase (PTS) Antibodies

The enzyme encoded by PTS catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Additionally we are shipping PTS Proteins (17) and PTS Kits (3) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PTS 29498 P27213
PTS 19286 Q9R1Z7
PTS 5805 Q03393
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Top anti-PTS Antibodies at antibodies-online.com

Showing 10 out of 30 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Mouse Un-conjugated EIA, WB 0.1 mL Log in to see 6 to 8 Days
$412.50
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB WB Image Sample (50 ug of whole cell lysate) A: mouse stomach 15% SDS PAGE antibody diluted at 1:1000 WB Image Sample (30 ug of whole cell lysate) A: H1299 15% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Mouse Un-conjugated ELISA, WB 100 μL Log in to see 8 to 10 Days
$478.50
Details
Human Rabbit Un-conjugated ICC, IHC (p), WB   100 μL Log in to see 8 to 10 Days
$507.83
Details
Human Rabbit Un-conjugated IP, WB Immunoprecipitation of PTS transfected lysate using anti-PTS MaxPab rabbit polyclonal antibody and Protein A Magnetic Bead , and immunoblotted with PTS MaxPab rabbit polyclonal antibody (D01) . Western Blot analysis of PTS expression in transfected 293T cell line by PTS MaxPab polyclonal antibody.Lane 1: PTS transfected lysate(16.40 KDa).Lane 2: Non-transfected lysate. 100 μL Log in to see 9 Days
$418.57
Details
Human Rabbit Un-conjugated ICC, IF, IHC (fp), WB 100 μL Log in to see 6 to 11 Days
$485.71
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (37.11 KDa) . 50 μL Log in to see 9 Days
$298.57
Details
Human Rabbit Un-conjugated WB   50 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB Western Blot analysis of PTS expression in transfected 293T cell line by PTS MaxPab polyclonal antibody.Lane 1: PTS transfected lysate(16.40 KDa).Lane 2: Non-transfected lysate. 100 μg Log in to see 9 Days
$418.57
Details

PTS Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Mouse (Murine)
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Human ,
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Top referenced anti-PTS Antibodies

  1. Human Monoclonal PTS Primary Antibody for EIA, WB - ABIN567625 : Spoonamore, Roberts, Heroux, Bandarian: Structure of a 6-pyruvoyltetrahydropterin synthase homolog from Streptomyces coelicolor. in Acta crystallographica. Section F, Structural biology and crystallization communications 2008 (PubMed)

More Antibodies against PTS Interaction Partners

Mouse (Murine) 6-Pyruvoyltetrahydropterin Synthase (PTS) interaction partners

  1. biopterin contents in the brains of these knock-out mice were moderately decreased from postnatal day 0 (P0) and remained constant up to P21 (show D4S234E Antibodies)

  2. ptps has a role in 6-pyruvoyltetrahydropterin synthase- or BH4-biosynthetic activity with IGF-1 (show IGF1 Antibodies)

Human 6-Pyruvoyltetrahydropterin Synthase (PTS) interaction partners

  1. Severe neurological impairment from BH4 deficiency could be prevented by newborn screening for hyperphenylalaninemia (HPA (show HPSE Antibodies)) and proper metabolic management.

  2. A total of 43 mutations were identified in the PTS gene in a screen of East Asian populations, comprising 22 previously reported mutations and 21 new discovered mutations.

  3. The mutant characterization of PTPS gene was coincident with other early studies in Chinese. The novel mutation L127F was considered as a pathogenetic mutation and associated with severe clinical phenotype.

  4. Our data show that PTPS induction is necessary for optimized BH4 synthesis in cytokine-stimulated human coronary artery endothelial cells and point to IL-1beta (show IL1B Antibodies) as a leading cytokine in this process.

  5. Human PTS was efficiently expressed in noradrenergic regions but only in a small number of dopaminergic neurons.

  6. Expression of PTS was significantly decreased in PD cases.

  7. We suggest that the serum prolactin (show PRL Antibodies) level may be a more sensitive marker than the CSF (show CSF2 Antibodies) HVA level to guide the dose adjustment of L-Dopa/carbidopa in the management of patients with PTPS deficiency.

PTS Antigen Profile

Protein Summary

The enzyme encoded by this gene catalyzes the elimination of inorganic triphosphate from dihydroneopterin triphosphate, which is the second and irreversible step in the biosynthesis of tetrahydrobiopterin from GTP. Tetrahydrobiopterin, also known as BH(4), is an essential cofactor and regulator of various enzyme activities, including enzymes involved in serotonin biosynthesis and NO synthase activity. Mutations in this gene result in hyperphenylalaninemia.

Gene names and symbols associated with PTS

  • 6-pyruvoyltetrahydropterin synthase (PTS) antibody
  • 6-pyruvoyltetrahydropterin synthase (pts) antibody
  • 6-pyruvoyltetrahydropterin synthase (Pts) antibody
  • 6-pyruvoyltetrahydropterin synthase (azo3118) antibody
  • 6-pyruvoyltetrahydropterin synthase (Xfasm12_0164) antibody
  • 6-pyruvoyltetrahydropterin synthase (Huta_2000) antibody
  • 6-pyruvoyltetrahydropterin synthase (Cyan8802_3683) antibody
  • 6-pyruvoyltetrahydropterin synthase (ptsA) antibody
  • 6-pyruvoyltetrahydropterin synthase (Nmag_3513) antibody
  • 6-pyruvoyltetrahydropterin synthase (DICPUDRAFT_151723) antibody
  • 6-pyruvoyl-tetrahydropterin synthase (Pts) antibody
  • DDBDRAFT_0232952 antibody
  • DDB_0232952 antibody
  • PTPS antibody
  • Pts antibody
  • zgc:162276 antibody

Protein level used designations for PTS

6-pyruvoyltetrahydropterin synthase , 6-pyruvoyl tetrahydrobiopterin synthase , putative 6-pyruvoyltetrahydropterin synthase , PTP synthase , PTPS

GENE ID SPECIES
374144 Gallus gallus
495178 Xenopus laevis
506860 Bos taurus
611326 Canis lupus familiaris
692791 Bombyx mori
711642 Macaca mulatta
739126 Pan troglodytes
2734138 Bdellovibrio bacteriovorus HD100
4607798 Azoarcus sp. BH72
6121154 Xylella fastidiosa M12
8384294 Halorhabdus utahensis DSM 12940
8393025 Cyanothece sp. PCC 8802
8621869 Dictyostelium discoideum AX4
8826381 Natrialba magadii ATCC 43099
100073330 Danio rerio
100190535 Taeniopygia guttata
10500652 Dictyostelium purpureum
29498 Rattus norvegicus
19286 Mus musculus
5805 Homo sapiens
100171600 Pongo abelii
Selected quality suppliers for anti-PTS (PTS) Antibodies
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