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6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 Proteins (PFKFB1)

PFKFB1 encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. Additionally we are shipping 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 Antibodies (68) and 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 Kits (7) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
PFKFB1 5207 P16118
PFKFB1 18639 P70266
PFKFB1 24638 P07953
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Top 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 Proteins at antibodies-online.com

Showing 9 out of 10 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
HOST_HEK-293 Cells Human His tag   50 μg Log in to see 5 Days
$522.50
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details
Yeast Rat His tag   1 mg Log in to see 56 to 66 Days
$3,325.67
Details
HOST_Baculovirus infected Insect Cells Human GST tag   50 μg Log in to see 10 to 12 Days
$570.24
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   50 μg Log in to see 9 to 11 Days
$229.85
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

PFKFB1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , , , ,
,
Mouse (Murine)

Rat (Rattus)

More Proteins for 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) Interaction Partners

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) interaction partners

  1. Insulin (show INS Proteins) resistance in obese boys leads to up-regulation of INSIG2 (show INSIG2 Proteins) gene expression as well as to down-regulation of PFKFB1, PFKFB3 (show PFKFB3 Proteins), and HK2 (show HK2 Proteins) genes in the blood cells as compared to obese patients with normal insulin (show INS Proteins) sensitivity.

  2. Results describe structural differences between two isozymes of 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase from liver and testis.

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) interaction partners

  1. Data show that cardiac overexpression of kinase-deficient PFK-2 reduces cardiac glycolysis that produced negative consequences to the heart including hypertrophy, fibrosis, and reduced cardiomyocyte function.

6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 1 (PFKFB1) Protein Profile

Protein Summary

This gene encodes a member of the family of bifunctional 6-phosphofructo-2-kinase:fructose-2,6-biphosphatase enzymes. The enzyme forms a homodimer that catalyzes both the synthesis and degradation of fructose-2,6-biphosphate using independent catalytic domains. Fructose-2,6-biphosphate is an activator of the glycolysis pathway and an inhibitor of the gluconeogenesis pathway. Consequently, regulating fructose-2,6-biphosphate levels through the activity of this enzyme is thought to regulate glucose homeostasis. Multiple alternatively spliced transcript variants have been found for this gene.

Gene names and symbols associated with PFKFB1

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (pfkfb1)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (PFKFB1)
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 (Pfkfb1)
  • F6PK protein
  • HL2K protein
  • Pfkfb01 protein
  • PFKFB1 protein
  • PFRX protein
  • wu:fi11h10 protein
  • zgc:55328 protein

Protein level used designations for PFKFB1

6-phosphofructo-2-kinase/fructose 2,6-bisphosphatase , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1-like , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 , 6PF-2-K/Fru-2,6-P2ASE liver isozyme , 6PF-2-K/Fru-2,6-P2ase 1 , PFK/FBPase 1 , fructose-6-phosphate,2-kinase:fructose-2,6-bisphosphatase , 6PF-2-K/Fru-2,6-P2ase liver isozyme , PFK-2/FBPase-2 gene A , 6-phosphofructo-2 kinase /fructose-2,6-biphosphatase 1

GENE ID SPECIES
327453 Danio rerio
465657 Pan troglodytes
495408 Xenopus laevis
701969 Macaca mulatta
770873 Gallus gallus
100062514 Equus caballus
100434125 Pongo abelii
100475853 Ailuropoda melanoleuca
100014887 Monodelphis domestica
100078789 Ornithorhynchus anatinus
100345023 Oryctolagus cuniculus
100606264 Nomascus leucogenys
5207 Homo sapiens
18639 Mus musculus
24638 Rattus norvegicus
282304 Bos taurus
491903 Canis lupus familiaris
100233197 Sus scrofa
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