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anti-6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) Antibodies

Synthesis and degradation of fructose 2,6-bisphosphate.. Additionally we are shipping PFKFB4 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
PFKFB4 5210 Q16877
PFKFB4 270198 Q6DTY7
PFKFB4 54283 P25114
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Top anti-PFKFB4 Antibodies at antibodies-online.com

Showing 10 out of 26 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-PFKFB4 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: HepG2 cell lysate WB Suggested Anti-PFKFB4 Antibody  Positive Control: Lane 1:441 µg HEK293 lysate Lane 2: 041 µg H1299 lysate Primary Antibody Dilution: 1:0000Secondary Antibody: Goat anti-rabbit-HRP Secondry  Antibody Dilution: 1:0000Submitted by: Jose Luis Rosa, Universitat de Barcelona 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-PFKFB4 Pab (ABIN392786) is used in Western blot to detect PFKFB4 in mouse brain tissue lysate. FTS down-regulates HIF-1 and HIF-1-regulated proteins in GBM cells. GBM cell lines were incubated under hypoxia (1% O2) for the indicated periods with FTS and then processed for the determination of PFKFB4 by WB. Samples of total cell lysates were also immunoblotted with anti-tubulin antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB WB Image Sample (30μg whole cell lysate) A:MOLT4 , B:Raji , 10% SDS PAGE antibody diluted at 1:500 IHC-P Image PFKFB4 antibody [N3C3] detects PFKFB4 protein at cytosol on mouse middle brain by immunohistochemical analysis. Sample: Paraffin-embedded mouse middle brain. PFKFB4 antibody [N3C3] , dilution: 1:500. 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated IF, WB Anti-PFKFB4 mouse monoclonal antibody (ABIN2453452) immunofluorescent staining of COS7 cells transiently transfected by pCMV6-ENTRY PFKFB4 (RC201573). HEK293T cells were transfected with the pCMV6-ENTRY control (Left lane) or pCMV6-ENTRY PFKFB4 (Right lane) cDNA for 48 hrs and lysed. Equivalent amounts of cell lysates (5 µg per lane) were separated by SDS-PAGE and immunoblotted with anti-PFKFB4. 100 μL Log in to see 2 to 3 Days
$482.90
Details
Human Rabbit Un-conjugated WB PFKFB4 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Mouse Rabbit Un-conjugated WB   50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Biotin IHC, ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details

PFKFB4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Human ,
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Mouse (Murine)


Rat (Rattus)


Top referenced anti-PFKFB4 Antibodies

  1. Human Polyclonal PFKFB4 Primary Antibody for IHC (p), WB - ABIN392786 : Blum, Jacob-Hirsch, Amariglio, Rechavi, Kloog: Ras inhibition in glioblastoma down-regulates hypoxia-inducible factor-1alpha, causing glycolysis shutdown and cell death. in Cancer research 2005 (PubMed)
    Show all 4 references for ABIN392786

  2. Human Polyclonal PFKFB4 Primary Antibody for WB - ABIN2786782 : Bobarykina, Minchenko, Opentanova, Moenner, Caro, Esumi, Minchenko: Hypoxic regulation of PFKFB-3 and PFKFB-4 gene expression in gastric and pancreatic cancer cell lines and expression of PFKFB genes in gastric cancers. in Acta biochimica Polonica 2007 (PubMed)

More Antibodies against PFKFB4 Interaction Partners

Human 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) interaction partners

  1. The expression of PFKFB3 (show PFKFB3 Antibodies), PFKFB4, NAMPT (show NAMPT Antibodies), and TSPAN13 (show TSPAN13 Antibodies) is strongly up-regulated in pediatric glioma.

  2. Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.

  3. PFKFB4 suppresses oxidative stress and p62 (show GTF2H1 Antibodies) accumulation, without which autophagy is stimulated likely as a ROS (show ROS1 Antibodies) detoxification response.

  4. Data indicate that the PFKFB4 expressed in multiple transformed cells and tumors functions to synthesize F2,6BP.

  5. we found that the glycolytic enzyme PFKFB4 is essential for prostate cancer cell survival by maintaining the balance between the use of glucose for energy generation and the synthesis of antioxidants.

  6. PFKFB4 has an important role in the progression of non-muscle-invasive bladder cancer (

  7. PFKFB4 and HO-2 (show HMOX2 Antibodies) are expressed in a coordinated manner to maintain glucose homeostasis.

  8. Data suggest that molecular mechanism by which dihydrotestosterone induces Pfkfb4 (and thus glycolysis) during spermatogenesis involves stimulation of Sertoli cells to secrete FGF-2 (fibroblast growth factor 2 (show FGF2 Antibodies)); study uses recombinant human Pfkfb4.

  9. an essential role of PFKFB4 in the maintenance of brain cancer stem-like cells

  10. Sulforaphane is a potent inducer of apoptosis in hepatocellular carcinoma cells via PFKFB4-inhibition pathways.

Mouse (Murine) 6-phosphofructo-2-Kinase/fructose-2,6-Biphosphatase 4 (PFKFB4) interaction partners

  1. Inhibition of PFKFB4 suppresses glycolysis and proliferation of multiple human cancer cell lines.

PFKFB4 Antigen Profile

Protein Summary

Synthesis and degradation of fructose 2,6-bisphosphate.

Gene names and symbols associated with PFKFB4

  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (pfkfb4) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (PFKFB4) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (f264) antibody
  • 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 (Pfkfb4) antibody
  • C230090D14 antibody
  • MGC69186 antibody
  • MGC81068 antibody
  • PFKFB4 antibody
  • zgc:123288 antibody

Protein level used designations for PFKFB4

6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4 , 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4-like , 6-phosphofructo-2-kinase/fructose-2,6-biphosphatase-4 , 6PF-2-K/Fru-2,6-P2ase 4 , 6PF-2-K/Fru-2,6-P2ase testis-type isozyme , PFK/FBPase 4 , bifunctional enzyme with kinase and biphosphatase activities , 6PF-2-K/Fru-2,6-P2ASE testis-type isozyme

GENE ID SPECIES
407880 Xenopus (Silurana) tropicalis
432000 Xenopus laevis
460346 Pan troglodytes
534928 Bos taurus
556190 Danio rerio
100195507 Salmo salar
100345242 Oryctolagus cuniculus
100560960 Anolis carolinensis
5210 Homo sapiens
270198 Mus musculus
54283 Rattus norvegicus
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