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A Kinase (PRKA) Anchor Protein 1 Proteins (AKAP1)

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. Additionally we are shipping AKAP1 Antibodies (37) and AKAP1 Kits (27) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AKAP1 8165 Q92667
AKAP1 11640 O08715
Rat AKAP1 AKAP1 114124 O88884
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Top AKAP1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

AKAP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for A Kinase (PRKA) Anchor Protein 1 (AKAP1) Interaction Partners

Pig (Porcine) A Kinase (PRKA) Anchor Protein 1 (AKAP1) interaction partners

  1. The regulation of PKA localization by AKAP1 may be involved in meiotic resumption and oocyte maturation but not in meiotic incompetence of porcine growing oocytes.

Human A Kinase (PRKA) Anchor Protein 1 (AKAP1) interaction partners

  1. Functional characterization revealed an undescribed role for AMPK (show PRKAA1 Proteins)-dependent phosphorylation of AKAP1 in mitochondrial respiration.

  2. AKAP 149-PKA-PDE4A (show PDE4A Proteins) complex localization is related with YTX effect in K-562 cell line

  3. In the case of the beta2AR (show ADRB2 Proteins), this process is facilitated by the presence of A-Kinase Anchoring Proteins (AKAPs) that serve as scaffolding proteins for the L-type calcium channel and the beta2AR (show ADRB2 Proteins) complex.

  4. AKAP1 anchors Star mRNA at the mitochondria, thus stabilizing the translational complex at this organelle, a situation that might affect STAR production and steroidogenesis.

  5. In tumoural lymphocytes, yessotoxin decreases AKAP149 cytosolic expression and increases cAMP levels which leads to cell death.

  6. Shp2 is a component of the AKAP-Lbc complex and is inhibited by protein kinase A under pathological hypertrophic conditions in the heart.

  7. AMY-1 interacts with this and AKAP95 in the cytoplasm and the nucleus, respectively, and inhibits cAMP-dependent protein kinase activity by preventing binding of its catalytic subunit to A-kinase-anchoring protein (AKAP) complex.

  8. RIalpha (show PRKAR1A Proteins) and RIbeta (show PRKAR1B Proteins) homodimers as well as an RIalpha:RIbeta heterodimer and several of the mutants were able to bind to the R-binding domain of AKAP149/D-AKAP1

  9. AKAP149-regulated PP1 (show PPA1 Proteins) activity at the NE during G1 is required to maintain nuclear integrity and cell survival.

  10. both the constitutive and cAMP-induced release of TNFR1 exosome-like vesicles occur via PKA-dependent pathways that are regulated by the anchoring of RIIbeta to BIG2 via AKAP domains B and C

Mouse (Murine) A Kinase (PRKA) Anchor Protein 1 (AKAP1) interaction partners

  1. Data suggest that D-AKAP1 is a transmembrane protein in mitochondrial outer membrane; D-AKAP1 appears to participate in cAMP signaling; hydrophobicity of D-AKAP1 transmembrane domain regulates localization to either ER or mitochondria.

  2. db/db (show LEPR Proteins)/ mice

  3. NCX3 (show SLC8A3 Proteins) regulates mitochondrial calcium handling from the outer mitochondrial membrane through an AKAP121-anchored signaling complex.

  4. PKC and PKA regulate AChR dynamics at the neuromuscular junction of living mice.

  5. Activation of NOD1 (show NOD1 Proteins) induces lipolysis through NF-kappaB (show NFKB1 Proteins) and the lipolytic PKA activation in 3T3-L1 adipocytes.

  6. hypoxia induces fission of mitochondrial membranes, dependent on availability of protein AKAP121

  7. Six putative caspase (show CASP3 Proteins) substrates, including five novel proteins (ABCF1 (show ABCF1 Proteins), AKAP1, CPE (show CPE Proteins), DOPEY1 and GOPC1 (show GOPC Proteins)) that may be targeted specifically by the initiator caspases 8 and 10 during the early stages of apoptosis, were identified.[caspase 10 (show CASP10 Proteins)]

  8. AKAP121 regulates the response to stress in cardiomyocytes, and therefore AKAP121 downregulation might represent an important event contributing to the development of cardiac dysfunction.

  9. AKAP1 is a bifunctional helical element that is required for both ER and mitochondrion targeting.

  10. Purified tubulin (show TUBB Proteins) binds directly to S-AKAP84 but not to a deletion mutant lacking the mitochondrial targeting domain (MT) at residues 1-30.

AKAP1 Protein Profile

Protein Summary

The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.

Gene names and symbols associated with AKAP1

  • A kinase (PRKA) anchor protein 1 (AKAP1)
  • A kinase (PRKA) anchor protein 1b (akap1b)
  • A kinase (PRKA) anchor protein 1 (akap1)
  • A kinase (PRKA) anchor protein 1 (Akap1)
  • Akap protein
  • akap1 protein
  • Akap84 protein
  • AKAP121 protein
  • AKAP149 protein
  • C76494 protein
  • C81186 protein
  • D-AKAP1 protein
  • DAKAP1 protein
  • fa08b04 protein
  • PPP1R43 protein
  • PRKA1 protein
  • S-AKAP84 protein
  • SAKAP84 protein
  • TDRD17 protein
  • wu:fa08b04 protein

Protein level used designations for AKAP1

A kinase (PRKA) anchor protein 1 , A-kinase anchor protein 1 , A kinase anchor protein 1, mitochondrial , a kinase anchor protein 1, mitochondrial-like , a-kinase anchor protein 1, mitochondrial-like , A-kinase anchor protein 1, mitochondrial , A-kinase anchor protein 149 kDa , AKAP 149 , D-AKAP-1 , dual-specificity A-kinase anchoring protein 1 , protein kinase A anchoring protein 1 , protein kinase A1 , protein phosphatase 1, regulatory subunit 43 , spermatid A-kinase anchor protein 84 , tudor domain containing 17 , PRKA1 , S-AKAP , a kinase anchor protein 1, mitochondrial , dual specificity A-kinase-anchoring protein 1 , protein kinase A-anchoring protein 1 , spermatid A-kinase anchor protein , A-kinase anchor protein 121 kDa , AKAP 121 , S-AKAP84

GENE ID SPECIES
417668 Gallus gallus
455150 Pan troglodytes
480567 Canis lupus familiaris
532072 Bos taurus
556208 Danio rerio
100056722 Equus caballus
100379795 Xenopus (Silurana) tropicalis
100433971 Pongo abelii
100480229 Ailuropoda melanoleuca
100533549 Sus scrofa
100601193 Nomascus leucogenys
708500 Macaca mulatta
8165 Homo sapiens
100357677 Oryctolagus cuniculus
11640 Mus musculus
114124 Rattus norvegicus
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