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The protein encoded by AKAP2 binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. Additionally we are shipping AKAP2 Kits (9) and and many more products for this protein.
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Human Polyclonal AKAP2 Primary Antibody for ELISA, WB - ABIN1534207
Li, Liu, Chen, Jain, Vatner, Vatner, Kudej, Yan: Proteomic Mechanisms of Cardioprotection during Mammalian Hibernation in Woodchucks, Marmota Monax. in Journal of proteome research 2013
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AKAP2 is expressed in human prostates, its expression is elevated in metastatic prostate cancer.
Knocking down akap2 expression remarkably decreased tumorigenicity and metastatic ability of prostate cancer cells. AKAP2 may serve as a critical component of Calcitonin receptor (show CALCR Antibodies)-mediated oncogenic actions.
The AKAP2 protein is direct phosphorylation within a regulatory region of aquaporin-0 (show MIP Antibodies) to modulate water permeability.
distinct modes of AKAP (show AKAP1 Antibodies) binding may contribute to the more discriminating nature of the RIalpha (show PRKAR1A Antibodies) (protein kinase A isoform) and AKAP (show AKAP1 Antibodies) docking surface
The protein encoded by this gene binds to the regulatory subunit of protein kinase A and is found associated with the actin cytoskeleton. The encoded protein mediates signals carried by cAMP and may be involved in creating polarity in certain signaling processes. Three transcript variants encoding different isoforms have been found for this gene.
A kinase (PRKA) anchor protein 2
, A-kinase anchor protein 2-like
, a-kinase anchor protein 2-like
, A-kinase anchor protein 2
, protein kinase A anchoring protein 2
, protein kinase A2
, AKAP expressed in kidney and lung
, protein kinase A-anchoring protein 2