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The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. Additionally we are shipping AKAP6 Kits (9) and and many more products for this protein.
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Mouse (Murine) Polyclonal AKAP6 Primary Antibody for ELISA, WB - ABIN185202
McCartney, Little, Langeberg, Scott: Cloning and characterization of A-kinase anchor protein 100 (AKAP100). A protein that targets A-kinase to the sarcoplasmic reticulum. in The Journal of biological chemistry 1995
Show all 2 references for ABIN185202
two alternatively spliced forms of mAKAP are expressed: mAKAPalpha, the longer form, and mAKAPbeta. mAKAPalpha is preferentially expressed in brain
The association of AC5 (show ADCY5 Antibodies) with the AKAP6 complex is required for the regulation of cAMP second messenger controlling cardiac myocyte hypertrophy.
This study expands our understanding of the regulation of MEF2 (show MEF2A Antibodies) in skeletal muscle and identifies the mAKAP scaffold as a facilitator of MEF2 (show MEF2A Antibodies) transcription and myogenic differentiation.
Comparative analysis of the binding responses of mutations to mAKAP could provide important information about how these mutations modulate PKA and PDE4D3 signaling.
cAMP-stimulated protein phosphatase 2A activity associated with muscle A kinase-anchoring protein (show AKAP13 Antibodies) (mAKAP) signaling complexes inhibits the phosphorylation and activity of the cAMP-specific phosphodiesterase PDE4D3
mAKAP organized ubiquitin E3 ligases that managed the stability of HIF-1alpha (show HIF1A Antibodies) and optimally positioned it close to its site of action inside the nucleus
The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. This gene encodes a member of the AKAP family. The encoded protein is highly expressed in various brain regions and cardiac and skeletal muscle. It is specifically localized to the sarcoplasmic reticulum and nuclear membrane, and is involved in anchoring PKA to the nuclear membrane or sarcoplasmic reticulum.
A kinase (PRKA) anchor protein 6
, A-kinase anchor protein 6
, A-kinase anchor protein 6-like
, a-kinase anchor protein 6-like
, A-kinase anchoring protein alpha
, A-kinase anchoring protein beta
, anchor protein 6
, A-kinase anchor protein 100 kDa
, AKAP 100
, protein kinase A anchoring protein 6
, protein kinase A-anchoring protein 6