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ADAM Metallopeptidase Domain 23 Proteins (Adam23)

Adam23 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Additionally we are shipping Adam23 Antibodies (70) and Adam23 Kits (2) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
Adam23 23792 Q9R1V7
Adam23 8745 O75077
Rat Adam23 Adam23 301460  
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Top Adam23 Proteins at antibodies-online.com

Showing 4 out of 4 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Mouse rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.25 mg Log in to see 49 to 54 Days
$4,244.78
Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
Insect Cells Human rho-1D4 tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 0.5 mg Log in to see 49 to 54 Days
$6,041.49
Details

Adam23 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine) ,
,
Human ,
,

More Proteins for ADAM Metallopeptidase Domain 23 (Adam23) Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 23 (Adam23) interaction partners

  1. Interaction proteomics revealed the interactors of Caspr2 (show CNTNAP2 Proteins), including CNTN2 (show CNTN2 Proteins), KCNAs, members of the ADAM family (ADAM22 (show ADAM22 Proteins), ADAM23 and ADAM11 (show ADAM11 Proteins)), members of LGI family and MAGUKs (DLGs and MPPs (show MPHOSPH6 Proteins)).

  2. Adam23 knockdown up-regulates P27KIP1 (show CDKN1B Proteins) in P19 (show CDKN2D Proteins)/ADAM23 knockdown cells, one reason that P19 (show CDKN2D Proteins)/ADAM23 knockdown cells can differentiate into neurons without retinoic acid induction.

  3. Data suggest that leucine-rich glioma inactivated 3 (LGI3 (show LGI3 Proteins)) may be a candidate adipokine that is perturbed in obesity and suppresses adipogenesis through its receptor, ADAM23.

  4. Data suggest that LGI1 (show LGI1 Proteins) binding to ADAM23 is necessary to correctly pattern neuronal morphology, and altered anatomical patterning contributes to autosomal dominant partial epilepsy with auditory features.

  5. These results suggest ADAM23 may play roles in both early and later stage of neuronal differentiation.

  6. PrP(C (show PRNP Proteins)) is a novel molecular partner for ADAM23 in the nervous systems.

  7. Functional role of ADAM23 during lung cancer metastatic progression by negatively modulating alpha(v)beta(3) integrin activation.

Human ADAM Metallopeptidase Domain 23 (Adam23) interaction partners

  1. Our data provide evidence that ADAM23 plays a role in suppression of cancer cell progression through interaction with aVb3 integrin, and suggest that downregulation of ADAM23 in SP cells may contribute toward providing a cancer stem cell phenotype

  2. High ADAM23 gene methylation is associated with gastric tumor aggressiveness.

  3. quantification of CXCL12 (show CXCL12 Proteins) and ADAM23 methylation could be useful for the prediction of advanced stage of BC

  4. Intratumoral heterogeneity of ADAM23 promotes tumor growth and metastasis through LGI4 and nitric oxide signals.

  5. The expression level of ADAM23 is likely to be involved in the progression of non-small-cell lung carcinoma, and its downregulation is probably correlated with promoter methylation.

  6. a SP1 (show PSG1 Proteins) binding site (-202/-190) that binds SP1 (show PSG1 Proteins) at the proximal promoter of human ADAM23 gene was indentified.

  7. Together, these results indicate that ADAM23 down-regulation by methylation in brain tumors is a rare event and it may help explain why brain tumor metastases are rarely found elsewhere in the body.

  8. ADAM23 is frequently silenced in gastric cancers by homozygous deletion or aberrant promoter methylation.

  9. ADAM23 may be down-regulated by aberrant promoter hypermethylation during the progression of colorectal cancer.

  10. PrP(C (show PRNP Proteins)) is a novel molecular partner for ADAM23 in the nervous systems.

Adam23 Protein Profile

Protein Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. This gene is highly expressed in the brain and may function as an integrin ligand in the brain.

Gene names and symbols associated with Adam23

  • ADAM metallopeptidase domain 23 (ADAM23)
  • a disintegrin and metallopeptidase domain 23 (Adam23)
  • ADAM metallopeptidase domain 23 (Adam23)
  • AW046396 protein
  • MDC-3 protein
  • MDC3 protein

Protein level used designations for Adam23

ADAM 23 , MDC-3 , a disintegrin and metalloprotease domain 23 , disintegrin and metalloproteinase domain-containing protein 23 , metalloproteinase-like, disintegrin-like, and cysteine-rich protein 3 , a disintegrin and metallopeptidase domain 23

GENE ID SPECIES
100068579 Equus caballus
23792 Mus musculus
8745 Homo sapiens
100518044 Sus scrofa
531241 Bos taurus
301460 Rattus norvegicus
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