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anti-ADAM Metallopeptidase Domain 8 (ADAM8) Antibodies

ADAM8 encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Additionally we are shipping ADAM8 Kits (15) and ADAM8 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAM8 11501 Q05910
ADAM8 101 P78325
ADAM8 499285  
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Top anti-ADAM8 Antibodies at antibodies-online.com

Showing 10 out of 77 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Goat Un-conjugated ELISA, WB ABIN184726 staining (2µg/ml) of Human Brain lysate (RIPA buffer, 30µg total protein per lane). Primary incubated for 1 hour. Detected by western blot using chemiluminescence. 100 μg Log in to see 4 to 5 Days
$318.20
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ADAM8 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: PANC1 cell lysate WB Suggested Anti-ADAM8  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.2500  Positive Control: PANC1 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB ADAM8 Antibody (N-term) (ABIN657979) western blot analysis in NCI-H460 cell line lysates (35 µg/lane). This demonstrates the ADAM8 antibody detected the ADAM8 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Goat Un-conjugated ELISA, WB 100 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded mouse stomach labeled with Rabbit Anti ADAM8 Polyclonal Antibody, Unconjugated (ABIN755233) at 1:200 followed by conjugation to the secondary antibody and DAB staining Mouse splenocytes probed with Rabbit Anti-ADAM8 Polyclonal Antibody, Unconjugated . 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated WB WB Image Sample (30 ug of whole cell lysate) A: Raji 7.5% SDS PAGE antibody diluted at 1:500 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated IHC (p), WB Human Spleen: Formalin-Fixed, Paraffin-Embedded (FFPE) Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ADAM8 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADAM8 Antibodies

  1. Human Polyclonal ADAM8 Primary Antibody for WB - ABIN611315 : Barbara, Wrana, Letarte: Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-beta superfamily. in The Journal of biological chemistry 1999 (PubMed)
    Show all 4 references for ABIN611315

  2. Human Polyclonal ADAM8 Primary Antibody for ELISA, WB - ABIN184726 : Yoshiyama, Higuchi, Kataoka, Matsuura, Yamamoto: CD156 (human ADAM8): expression, primary amino acid sequence, and gene location. in Genomics 1997 (PubMed)

More Antibodies against ADAM8 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

  1. The important role of ADAM8 in the progression of hepatocellular carcinoma induced by diethylnitrosamine in mice

  2. ADAM8 mediates an enhanced invasiveness of neutrophils into injured muscle fibers by the removal of their adhesiveness to blood vessels after infiltration into interstitial tissues.

  3. ADAM8 has anti-inflammatory activities during allergic airway inflammation in mice

  4. overexpression of PrP(C (show PRNP Antibodies)) led to up-regulation of ADAM8, suggesting that PrP(C (show PRNP Antibodies)) may regulate its own alpha-cleavage through modulating ADAM8 activity.

  5. ADAM-8 appears to favour allergen-induced acute airway inflammation by promoting dendritic cell recruitment and CCL11 (show CCL11 Antibodies) and CCL22 (show CCL22 Antibodies) production.

  6. ADAM8 knockout mice did not display a bone phenotype in vivo but they did not increase RANKL (show TNFSF11 Antibodies) production, OCL (show OCLN Antibodies) formation, or calvarial fibrosis in response to tumor necrosis factor alpha (TNF-alpha (show TNF Antibodies)) in vivo.

  7. ADAM8 is involved in T cell maturation in the medulla but has a relatively minor impact on T cell development.

  8. The results of this study indicated an essential role for ADAM8 in modulating TNF-alpha (show TNF Antibodies) signaling in CNS diseases

  9. The study finds an increase in retinal re-vascularization but fewer neovascular tufts in the oxygen-induced retinopathy model and increased growth of heterotopically injected tumor cells in Adam8-/- mice compared with wild-type controls.

  10. ADAM8 plays a proinflammatory role in airway inflammation.

Human ADAM Metallopeptidase Domain 8 (ADAM8) interaction partners

  1. miR (show MLXIP Antibodies)-720 is elevated in serum of patients with ADAM8-high TNBC and, in a group with other miRNAs downstream of ADAM8, holds promise as a biomarker for early detection of or treatment response of ADAM8-positive triple-negative breast cancer

  2. ADAM8 causes temozolomide resistance in glioblastoma cells by enhancing pAkt/PI3K, pERK1/2, and cleavage of CD44 and HGF R/c-met

  3. ADAM8 promotes GC cell proliferation and invasion, and its expression is positively correlated with poor survival, indicating that it might be a promising target in GC therapy

  4. ADAM8 expression is associated with increased migration and invasiveness of pancreatic ductal adenocarcinoma cells.

  5. ADAM8 and endostatin (show COL18A1 Antibodies) play a role in osteosarcoma progression.

  6. Data indicate that fibronectin (show FN1 Antibodies) fragments (FN-fs) are present in adult ntervertebral disc (IVD (show IVD Antibodies)) from adult subjects, and ADAM-8, known to cleave FN, is present at the pericellular matrix of disc cells.

  7. Results show that ADAM8 is overexpressed in colorectal cancer and promotes cell growth.

  8. N-glycosylation is essential for processing, localization, stability, and activity of ADAM8.

  9. ADAM8 expression is increased in both severe asthma and COPD (show ARCN1 Antibodies) and associated with sputum total cell count and neutrophils. ADAM8 may facilitate neutrophil migration to the airways in severe asthma and COPD (show ARCN1 Antibodies).

  10. ADAM8 is abundantly expressed in breast tumors and derived metastases compared to normal tissue.

ADAM8 Antigen Profile

Protein Summary

This gene encodes a member of the ADAM (a disintegrin and metalloprotease domain) family. Members of this family are membrane-anchored proteins structurally related to snake venom disintegrins, and have been implicated in a variety of biological processes involving cell-cell and cell-matrix interactions, including fertilization, muscle development, and neurogenesis. The protein encoded by this gene may be involved in cell adhesion during neurodegeneration, and it is thought to be a target for allergic respiratory diseases, including asthma. Alternative splicing results in multiple transcript variants.

Gene names and symbols associated with ADAM8

  • a disintegrin and metalloproteinase domain 8 (LOC100304737) antibody
  • a disintegrin and metallopeptidase domain 8 (Adam8) antibody
  • ADAM metallopeptidase domain 8 (ADAM8) antibody
  • ADAM metallopeptidase domain 8 (Adam8) antibody
  • CD156 antibody
  • CD156a antibody
  • E430039A18Rik antibody
  • MS2 antibody
  • RGD1566394 antibody

Protein level used designations for ADAM8

a disintegrin and metalloproteinase domain 8 , ADAM 8 , a disintegrin and metalloprotease domain (ADAM) 8 , a disintegrin and metalloprotease domain 8 , cell surface antigen MS2 , disintegrin and metalloproteinase domain-containing protein 8 , macrophage cysteine-rich glycoprotein , human leukocyte differentiation antigen , a disintegrin and metallopeptidase domain 8

GENE ID SPECIES
100304737 Ictalurus punctatus
11501 Mus musculus
101 Homo sapiens
491699 Canis lupus familiaris
519652 Bos taurus
499285 Rattus norvegicus
100726804 Cavia porcellus
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