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anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) Antibodies

ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS13 Kits (27) and ADAMTS13 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS13 279028 Q769J6
ADAMTS13 11093 Q76LX8
ADAMTS13 362091  
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Top anti-ADAMTS13 Antibodies at antibodies-online.com

Showing 10 out of 69 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry: ADAMTS13 antibody staining of Formalin-Fixed Par... Western blot analysis: ADAMTS13 antibody staining of CEM cell line lys... 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ADAMTS13 Antibody (Center)(ABIN391641) i... Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADAMTS... 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ADAMTS13 is approximately 0... 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$489.50
Details
Human Mouse Un-conjugated FACS, ELISA, IP, WB   100 μg Log in to see 8 to 10 Days
$727.83
Details
Human Rabbit Alkaline Phosphatase (AP) ELISA, WB   200 μL Log in to see 8 to 10 Days
$969.83
Details
Human Mouse Un-conjugated IF, ELISA, WB   100 μg Log in to see 8 to 10 Days
$1,035.83
Details
Human Sheep Biotin WB   50 μg Log in to see 8 to 10 Days
$1,145.83
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ADAMTS13 is approximately 0... 100 μg Log in to see 9 Days
$430.00
Details
Human Sheep Un-conjugated ELISA, IP, WB   100 μg Log in to see 8 to 10 Days
$969.83
Details

ADAMTS13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Mouse (Murine) , ,

Human , , , ,
, , ,
Rat (Rattus) , ,

Top referenced anti-ADAMTS13 Antibodies

  1. Human Polyclonal ADAMTS13 Primary Antibody for EIA, IHC (p) - ABIN359601 : Levy, Nichols, Lian, Foroud, McClintick, McGee, Yang, Siemieniak, Stark, Gruppo, Sarode, Shurin, Chandrasekaran, Stabler, Sabio, Bouhassira, Upshaw, Ginsburg, Tsai: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. in Nature 2001 (PubMed)
    Show all 7 references for ABIN359601

  2. Human Polyclonal ADAMTS13 Primary Antibody for IHC (p), WB - ABIN391641 : Zheng, Chung, Takayama, Majerus, Sadler, Fujikawa: Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN391641

More Antibodies against ADAMTS13 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.

  2. ADAMTS13 substrate specificity

  3. Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.

  4. Data show that metalloendopeptidase (show THOP1 Antibodies) ADAMTS13 does not directly promote development of adipose tissue.

  5. findings provide further evidence on the pathophysiological role for the ADAMTS13/VWF (show VWF Antibodies) axis in atherosclerosis

  6. Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor (show VWF Antibodies) string formation under flow in a free-thiol-dependent manner.

  7. The results indicate that the microvascular process induced by ADAMTS13 deficiency triggers complement activation on platelets and the endothelium, which may contribute to formation of thrombotic microangiopathy.

  8. model of acute myocardial infarction in ADAMTS13 gene deleted (Adamts13 -/-) mice

  9. We hypothesize that ADAMTS13 protects brain from ischemia-reperfusion injury by regulating von Willebrand factor (show VWF Antibodies) -dependent inflammation as well as microvascular plugging

  10. Cyclophilin B (show PPIB Antibodies) activity regulated secretion and activity of ADAMTS13.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. Glycan stabilization of the VWF (show VWF Antibodies) A2 domain acts together with the Ca(2 (show CA2 Antibodies)+)binding site and vicinal cysteine disulfide bond to control unfolding and ADAMTS13 proteolysis.

  2. These data provide evidence for the involvement of CUB2 domain of ADAMTS13 - reactive CD4 (show CD4 Antibodies)(+)T cells in the etiology of acquired thrombotic thrombocytopenic purpura.

  3. Congenital thrombotic thrombocytopenic purpura (Upshaw-Schulman syndrome) caused by novel ADAMTS13 mutations.

  4. Adult-onset congenital thrombotic thrombocytopenic purpura caused by a novel compound heterozygous mutation of the ADAMTS13 gene.

  5. Reduced ADAMTS13 activity together with increased VWF (show VWF Antibodies) levels were especially notable in patients with active disease and with aPLs.

  6. Disappearing acts of ADAMTS13.

  7. Implementation of a rapid turnaround assay for ADAMTS13 resulted in a significant reduction in plasma utilization for patients with suspected TTP, without an increase in mortality

  8. Increase of von Willebrand factor (show VWF Antibodies) is associated with the risk of platelet thrombosis within the allograft during Lung Transplantation.

  9. Review/Meta-analysis: Low ADAMTS-13 levels are associated with an increased risk of myocardial infarction.

  10. ADAMTS13 variants and ADAMTS13 activity do not contribute to an increased risk of preeclampsia in the general population

ADAMTS13 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Gene names and symbols associated with ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (LOC100226372) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (ADAMTS12) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM-TS13 antibody
  • ADAMTS-13 antibody
  • ADAMTS12 antibody
  • ADAMTS13 antibody
  • C9orf8 antibody
  • Gm710 antibody
  • vWF-CP antibody
  • VWFCP antibody

Protein level used designations for ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like , A disintegrin and metalloproteinase with thrombospondin motifs 13-like , ADAM metallopeptidase with thrombospondin type 1 motif, 12 , A disintegrin and metalloproteinase with thrombospondin motifs 12 , A disintegrin and metalloproteinase with thrombospondin motifs 13 , ADAM-TS 13 , ADAM-TS13 , ADAMTS-13 , ADAMTS13 isoform IAP-b , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , vWF-CP mRNA for von Willebrand factor-cleaving , vWF-cleaving protease , von Willebrand factor-cleaving protease , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

GENE ID SPECIES
100069281 Equus caballus
100320289 Danio rerio
100404947 Callithrix jacchus
100481099 Ailuropoda melanoleuca
100226372 Taeniopygia guttata
427428 Gallus gallus
461952 Pan troglodytes
479369 Canis lupus familiaris
525276 Bos taurus
701750 Macaca mulatta
100068281 Equus caballus
279028 Mus musculus
11093 Homo sapiens
100630922 Canis lupus familiaris
532272 Bos taurus
362091 Rattus norvegicus
100343027 Oryctolagus cuniculus
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