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anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) Antibodies

ADAMTS13 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAMTS13 Kits (27) and ADAMTS13 Proteins (5) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS13 279028 Q769J6
ADAMTS13 11093 Q76LX8
ADAMTS13 362091  
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Top anti-ADAMTS13 Antibodies at antibodies-online.com

Showing 10 out of 83 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Immunohistochemistry: ADAMTS13 antibody staining of Formalin-Fixed Paraffin-Embedded Human hepatocarcinoma followed by peroxidase-conjugation to the secondary antibody and DAB staining. Western blot analysis: ADAMTS13 antibody staining of CEM cell line lysates (35 µg/lane). ADAMTS13 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of anti-ADAMTS13 Antibody (Center)(ABIN391641) in CEM cell line lysates (35 µg/lane). ADAMTS13 (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human hepatocarcinoma with ADAMTS13 Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated WB Detection of Recombinant Human Adam-TS13 by Western Blot. Samples: Purified recombinant Adam-TS13. Antibody: ABIN152016 used at the indicated concentrations. Detection: Chemiluminescence with an exposure time of approximately 30 seconds. 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Goat Un-conjugated WB 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Goat Un-conjugated IP, WB 100 μL Log in to see 5 to 7 Days
$486.94
Details
Human Rabbit Un-conjugated ELISA, IHC, IHC (p), WB   0.2 mL Log in to see 5 to 7 Days
$408.19
Details
Human Mouse Un-conjugated ELISA Detection limit for recombinant GST tagged ADAMTS13 is approximately 0.1 ng/mL as a capture antibody. 0.1 mg Log in to see 8 to 11 Days
$450.00
Details
Human Rabbit Un-conjugated ELISA, WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Mouse Un-conjugated FACS, IP, WB Detection of ADAMTS13 in HUVEC Human Cells by Flow Cytometry. HUVEC human umbilical vein endothelial cells were stained with Mouse Anti-Human ADAMTS13 Monoclonal Antibody. To facilitate intracellular staining, cells were fixed with paraformaldehyde and permeabilized with saponin. 100 μg Log in to see 6 to 7 Days
$333.38
Details
Human Mouse Un-conjugated EIA, WB   0.1 mg Log in to see 6 to 8 Days
$500.50
Details

ADAMTS13 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADAMTS13 Antibodies

  1. Human Polyclonal ADAMTS13 Primary Antibody for EIA, IHC (p) - ABIN359601 : Levy, Nichols, Lian, Foroud, McClintick, McGee, Yang, Siemieniak, Stark, Gruppo, Sarode, Shurin, Chandrasekaran, Stabler, Sabio, Bouhassira, Upshaw, Ginsburg, Tsai: Mutations in a member of the ADAMTS gene family cause thrombotic thrombocytopenic purpura. in Nature 2001 (PubMed)
    Show all 7 references for ABIN359601

  2. Human Polyclonal ADAMTS13 Primary Antibody for ELISA, IHC - ABIN4278265 : Ganburged, Suda, Saito, Yamazaki, Isokawa, Moriyama: Dilated capillaries, disorganized collagen fibers and differential gene expression in periodontal ligaments of hypomorphic fibrillin-1 mice. in Cell and tissue research 2010 (PubMed)
    Show all 3 references for ABIN4278265

  3. Human Polyclonal ADAMTS13 Primary Antibody for IHC (p), WB - ABIN391641 : Zheng, Chung, Takayama, Majerus, Sadler, Fujikawa: Structure of von Willebrand factor-cleaving protease (ADAMTS13), a metalloprotease involved in thrombotic thrombocytopenic purpura. in The Journal of biological chemistry 2001 (PubMed)
    Show all 3 references for ABIN391641

More Antibodies against ADAMTS13 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. Results also suggest that Toxoplasma gondii-mediated apoptosis might play a pivotal role and a different type of role in the mechanism of neurodegeneration and neuropathology in the process of toxoplasma encephalitis. Furthermore, expression of ADAMTS-13 might give an idea of the progress and is critical for diagnosis of this disease.

  2. Letter: deficiency of ADAMTS13 results in increased formation of venous thrombosis in mice.

  3. ADAMTS13 substrate specificity

  4. Data indicate that the p.D187H mutation impairs ADAMTS13 activity and secretion and may contribute to thrombotic thrombocytopenic purpura.

  5. Data show that metalloendopeptidase (show THOP1 Antibodies) ADAMTS13 does not directly promote development of adipose tissue.

  6. findings provide further evidence on the pathophysiological role for the ADAMTS13/VWF (show VWF Antibodies) axis in atherosclerosis

  7. Carboxyl terminus of ADAMTS13 directly inhibits platelet aggregation and ultra large von Willebrand factor (show VWF Antibodies) string formation under flow in a free-thiol-dependent manner.

  8. The results indicate that the microvascular process induced by ADAMTS13 deficiency triggers complement activation on platelets and the endothelium, which may contribute to formation of thrombotic microangiopathy.

  9. model of acute myocardial infarction in ADAMTS13 gene deleted (Adamts13 -/-) mice

  10. We hypothesize that ADAMTS13 protects brain from ischemia-reperfusion injury by regulating von Willebrand factor (show VWF Antibodies) -dependent inflammation as well as microvascular plugging

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 13 (ADAMTS13) interaction partners

  1. von Willebrand factor (show VWF Antibodies) and ADAMTS-13 are associated with the occurrence of venous thromboembolism in patients with cancer.

  2. ADAMTS13 does not appear to be associated to disease severity or the hemodynamic derangement in patients with cirrhosis.

  3. ADAMTS-13 mutations differentiate between acute thrombotic microangiopathies

  4. We found a high prevalence of hereditary thrombotic thrombocytopenic purpura in central Norway and an apparently different penetrance of ADAMTS-13 mutations.

  5. data suggest that increased levels of VWF (show VWF Antibodies) and reduced levels of ADAMTS13 activity may contribute to the pathogenesis of cerebral infarction.

  6. ADAMTS13 is the key protease that regulates the multimeric state of VWF (show VWF Antibodies). Without ADAMTS13, VWF (show VWF Antibodies) multimers can grow to pathologically large sizes. This is a risk factor for the life-threatening condition thrombotic thrombocytopenic purpura (TTP)

  7. Stroke in human immunodeficiency virus infection is associated with a prothrombotic state, characterized by elevated von Willebrand factor (show VWF Antibodies) and low ADAMTS13 levels

  8. An in vitro model for LVAD associated aVWD demonstrated that ADAMTS-13 and platelets contribute to the depletion of HMWM of VWF (show VWF Antibodies).

  9. Case Report: D173G mutation in the catalytic domain of ADAMTS-13, never described before, causes a severe form of Upshaw-Schulman syndrome.

  10. Type 2B mutations localized in the A1 domain could enhance the sensitivity to ADAMTS13-mediated proteolysis. When GPIbalpha (show GP1BA Antibodies) participated, there was a dramatically increased proteolytic cleavage of VWF (show VWF Antibodies) by ADAMTS13 to rVWF-WT, excluding some type 2B mutants.

ADAMTS13 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene is the von Willebrand Factor (vWF)-cleaving protease, which is responsible for cleaving at the site of Tyr842-Met843 of the vWF molecule. A deficiency of this enzyme is associated with thrombotic thrombocytopenic purpura. Alternative splicing of this gene generates multiple transcript variants encoding different isoforms.

Gene names and symbols associated with ADAMTS13

  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (LOC100226372) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (ADAMTS12) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (Adamts13) antibody
  • ADAM-TS13 antibody
  • ADAMTS-13 antibody
  • ADAMTS12 antibody
  • ADAMTS13 antibody
  • C9orf8 antibody
  • Gm710 antibody
  • vWF-CP antibody
  • VWFCP antibody

Protein level used designations for ADAMTS13

ADAM metallopeptidase with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 isoform 1 preproprotein-like , A disintegrin and metalloproteinase with thrombospondin motifs 13-like , ADAM metallopeptidase with thrombospondin type 1 motif, 12 , A disintegrin and metalloproteinase with thrombospondin motifs 12 , A disintegrin and metalloproteinase with thrombospondin motifs 13 , ADAM-TS 13 , ADAM-TS13 , ADAMTS-13 , ADAMTS13 isoform IAP-b , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , vWF-CP mRNA for von Willebrand factor-cleaving , vWF-cleaving protease , von Willebrand factor-cleaving protease , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 13

GENE ID SPECIES
100069281 Equus caballus
100320289 Danio rerio
100404947 Callithrix jacchus
100481099 Ailuropoda melanoleuca
100226372 Taeniopygia guttata
427428 Gallus gallus
461952 Pan troglodytes
479369 Canis lupus familiaris
525276 Bos taurus
701750 Macaca mulatta
100068281 Equus caballus
279028 Mus musculus
11093 Homo sapiens
100630922 Canis lupus familiaris
532272 Bos taurus
362091 Rattus norvegicus
100343027 Oryctolagus cuniculus
Selected quality suppliers for anti-ADAMTS13 (ADAMTS13) Antibodies
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