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ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) ELISA Kits

ADAMTS4 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motif) protein family. Additionally we are shipping ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Antibodies (136) and ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Proteins (8) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ADAMTS4 361332  
ADAMTS4 240913 Q8BNJ2
ADAMTS4 9507 O75173
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Top ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 ELISA Kits at antibodies-online.com

Showing 10 out of 41 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 0.128 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$736.84
Details
Rat 1.15 ng/mL 0.15-10 ng/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details
Mouse 0.78 ng/ml 200-3.13 ng/mL   96 Tests Log in to see 11 to 13 Days
$910.56
Details
Cow 0.78 ng/ml 200-3.13 ng/mL   96 Tests Log in to see 11 to 13 Days
$1,026.67
Details
Rabbit 0.115 ng/mL 0.31-20 ng/mL 96 Tests Log in to see 9 to 11 Days
$800.00
Details
Dog
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Goat
  96 Tests Log in to see 11 to 13 Days
$801.43
Details
Cow
  96 Tests Log in to see 11 to 13 Days
$817.14
Details
Please inquire
1 kit Log in to see 2 to 3 Days
$502.70
Details
Human
  96 Tests Log in to see 11 to 13 Days
$785.71
Details

Top referenced ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 ELISA Kits

  1. Human ADAMTS4 ELISA Kit for Sandwich ELISA - ABIN649162 : Zha, Chen, Xu, Zhang, Li, Zhao, Cui: Elevated level of ADAMTS4 in plasma and peripheral monocytes from patients with acute coronary syndrome. in Clinical research in cardiology : official journal of the German Cardiac Society 2010 (PubMed)
    Show all 7 references for ABIN649162

  2. ABIN1882391 : Moncada-Pazos, Obaya, Viloria, López-Otín, Cal: The nutraceutical flavonoid luteolin inhibits ADAMTS-4 and ADAMTS-5 aggrecanase activities. in Journal of molecular medicine (Berlin, Germany) 2011 (PubMed)
    Show all 5 references for ABIN1882391

More ELISA Kits for ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Interaction Partners

Rabbit ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. a single injection of ADAMTS5 (show ADAMTS5 ELISA Kits) siRNA induced the suppression of degradation in rabbit nucleus pulposus tissues

Horse (Equine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Studies suggest that miR (show MYLIP ELISA Kits)-140 is an important regulator of cartilage development and homeostasis in cord blood-derived mesenchymal stromal cells (eCB-MSCs) that may act, in part, through the regulation of CXCL12 (show CXCL12 ELISA Kits) and ADAMTS-5 (show ADAMTS5 ELISA Kits).

  2. ADAMTS5 (show ADAMTS5 ELISA Kits) is present in degenerative suspensory ligament desmitis as a high molecular weight complex

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. ADAMTS4 participates in the regulation of muscle development in cattle.

  2. aggrecanase activity (a) is responsible for early TNFalpha (show TNF ELISA Kits)-dependent aggrecan (show ACAN ELISA Kits) cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration.

  3. ADAMTS4 and ADAMTS5 (show ADAMTS5 ELISA Kits) are inhibited by alpha2-macroglobulin (show A2M ELISA Kits)

  4. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 (show ADAMTS5 ELISA Kits)

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Results show that ADAMTS15 (show ADAMTS15 ELISA Kits) and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development

  2. aggrecan (show ACAN ELISA Kits) and brevican (show BCAN ELISA Kits) proteolysis is compensated in Adamts4-/- or Adamts5 (show ADAMTS5 ELISA Kits)-/- mice by ADAMTS (show ADAMTS1 ELISA Kits) proteoglycanase (show MMP3 ELISA Kits) family members but a threshold of versican (show Vcan ELISA Kits) proteolysis is sensitive to the loss of a single ADAMTS (show ADAMTS1 ELISA Kits) proteoglycanase (show MMP3 ELISA Kits) during spinal cord injury

  3. The serine protease (show F2 ELISA Kits) tissue plasminogen activator (tPA (show PLAT ELISA Kits)) and two matrix metalloproteinases, ADAMTS-4 and ADAMTS-5 (show ADAMTS5 ELISA Kits), were identified as Reelin (show RELN ELISA Kits) cleaving enzymes.

  4. ADAMTS-4 cleaves Reelin (show RELN ELISA Kits) in an isoform-specific manner. Among ADAMTS-4 isoforms, p50 (show LSP1 ELISA Kits) cleaves the N-t site only, while p75 (show NGFR ELISA Kits) cleaves both sites.

  5. Data demonstrate that Adamts1 (show ADAMTS1 ELISA Kits) and Adamts4 play redundant and essential roles in perinatal kidney development.

  6. Drastic down-regulation of Adamts4 observed at both E16 (show SLC7A5 ELISA Kits) and E18; RT-PCR revealed post-natal reduction in expression (Adamts4, 1/3). Results suggest down-regulation of gene is important factor in normal odontogenesis in dental papillae.

  7. proteolysis of hevin by ADAMTS4 in the mouse cerebellum is important for the normal development of this tissue

  8. ADAMTS1 (show ADAMTS1 ELISA Kits), ADAMTS4, and ADAMTS5 (show ADAMTS5 ELISA Kits) are expressed in patterns that relate to the expression pattern of versican (show Vcan ELISA Kits) in granulosa cells of small follicles, expanded cumulus cell-oocyte complexes, and endothelial cells of the ovary.

  9. ADAMTS-5 (show ADAMTS5 ELISA Kits) is entirely responsible for cleavage in the interglobular domain, but cleavage in the chondroitin sulfate-rich region may be driven by ADAMTS-4

  10. comparison of aggrecan (show ACAN ELISA Kits) loss with aggrecan (show ACAN ELISA Kits) processing in mice with single and double deletions of ADAMTS-4 and -5 activity (Deltacat)

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. progesterone acts via the progesterone receptor (show PGR ELISA Kits) to modulate ADAMTS 1 (show ADAMTS1 ELISA Kits) and 4 levels in ovarian cancer cell lines.

  2. ADAMTS4 may be responsible for the pathogenesis of atherosclerosis. ADAMTS4 serum levels were also higher in diabetic cases. There is an association between ADAMTS4 and TGFb1 (show TGFB1 ELISA Kits) serum levels in the progression of atherosclerosis in coronary artery disease.

  3. Evaluate ADAMTS-4 and ADAMTS-5 (show ADAMTS5 ELISA Kits) immunohistochemical expression in human TMJ discs from patients affected by internal derangement.

  4. These data demonstrate that the antibody is specific to ADAMTS4 and ADAMTS5 (show ADAMTS5 ELISA Kits) and inhibits their aggrecanase activity at molecular and cellular levels.

  5. ADAMTS4 is largely associated with synapses, and is the main brevican (show BCAN ELISA Kits)-processing protease.

  6. ADAMTS-4 is a potential biomarker and an early diagnostic indicator of knee osteoarthritis.

  7. A positive feedback loop involving sSema4D/IL-6 (show IL6 ELISA Kits) and TNFalpha (show TNF ELISA Kits)/ADAMTS-4 may contribute to the pathogenesis of rheumatoid arthritis.

  8. CCN1 (show CCNA2 ELISA Kits) suppresses ADAMTS-4 activity and that CCN1 (show CCNA2 ELISA Kits) overexpression is directly correlated with chondrocyte cloning in osteoarthritis cartilage. The TGFbeta (show TGFB1 ELISA Kits)/CCN1 (show CCNA2 ELISA Kits) axis plays a role in chondrocyte cluster formation through inhibition of ADAMTS-4.

  9. Our results indicate that miR (show MLXIP ELISA Kits)-125b plays an important role in regulating the expression of ADAMTS-4 in human chondrocytes

  10. We conclude that the upregulation of TNF-alpha (show TNF ELISA Kits) and ADAMTS-5 (show ADAMTS5 ELISA Kits), but not ADAMTS-4, may play an important role in degenerative cartilage endplate-induced low back pain.

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antigen Profile

Antigen Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene lacks a C-terminal TS motif. It is responsible for the degradation of aggrecan, a major proteoglycan of cartilage, and brevican, a brain-specific extracellular matrix protein. The cleavage of aggrecan and brevican suggests key roles of this enzyme in arthritic disease and in the central nervous system, potentially, in the progression of glioma.

Gene names and symbols associated with ADAMTS4

  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) antibody
  • aggrecanase-1 (ADAMTS-4) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (Adamts19) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4) antibody
  • ADAMTS-like 4 (ADAMTSL4) antibody
  • 3830423K05 antibody
  • ADAM-TS4 antibody
  • ADAMTS-2 antibody
  • ADAMTS-4 antibody
  • ADAMTS-11 antibody
  • ADAMTS4 antibody
  • ADAMTS5 antibody
  • ADAMTS13 antibody
  • ADMP-1 antibody
  • DKFZp469J0817 antibody
  • mKIAA0688 antibody

Protein level used designations for ADAMTS4

ADAM metallopeptidase with thrombospondin type 1 motif, 4 , aggrecanase-1 , A disintegrin and metalloproteinase with thrombospondin motifs 4-like , A disintegrin and metalloproteinase with thrombospondin motifs 19 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) , ADAM metallopeptidase with thrombospondin type 1 motif, 5 , ADAM metallopeptidase with thrombospondin type 1 motif, 19-like , aggrecanase-2 , A disintegrin and metalloproteinase with thrombospondin motifs 4 , ADAM-TS 4 , ADAMTS-4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 , ADAM-TS4 , Aggrecanase , a disintegrin and metallopeptidase with thrombospondin motifs 4 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 , ADMP-1 , disintegrin and metalloproteinase with thrombospondin motifs 2

GENE ID SPECIES
457453 Pan troglodytes
719927 Macaca mulatta
100008765 Oryctolagus cuniculus
100033914 Equus caballus
100171426 Pongo abelii
100409334 Callithrix jacchus
100482466 Ailuropoda melanoleuca
100606067 Nomascus leucogenys
361332 Rattus norvegicus
415600 Gallus gallus
417152 Gallus gallus
427971 Gallus gallus
462039 Pan troglodytes
473153 Pan troglodytes
473935 Pan troglodytes
487713 Canis lupus familiaris
537961 Bos taurus
705362 Macaca mulatta
707672 Macaca mulatta
100008799 Oryctolagus cuniculus
100066005 Equus caballus
240913 Mus musculus
9507 Homo sapiens
66015 Rattus norvegicus
286806 Bos taurus
488651 Canis lupus familiaris
100712995 Cavia porcellus
101106565 Ovis aries
100514576 Sus scrofa
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