anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antibodies

ADAMTS4 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Additionally we are shipping ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Kits (42) and ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Proteins (9) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS4 240913 Q8BNJ2
ADAMTS4 9507 O75173
ADAMTS4 66015 Q9ESP7
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Top anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Antibodies at antibodies-online.com

Showing 10 out of 166 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Cow Rabbit Un-conjugated IHC, WB <b>WB Suggested Anti-ADAMTS4 Antibody Titration: </b>0.2-1 ug/ml<br><b>Positive Control: </b>HepG2 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Cow Rabbit Un-conjugated WB <b>Host: </b>Rabbit<br><b>Target Name: </b>Adamts4<br><b>Antibody Dilution: </b>1.0ug/ml<br><b>Sample Tissue: </b>Rat Kidney Host: Rabbit <br /> Target Name: Adamts4 <br /> Antibody Dilution: 1.0 µg/mL <br /> Sample Tissue: Rat Kidney 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) in mouse cerebellum tissue lysates (35ug/lane). ADAMTS4 (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB Western blot analysis of anti-ADAMTS4 Antibody (C-term) (ABIN391642) in mouse cerebellum tissue lysates (35 µg/lane). ADAMTS4 (arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated ELISA, IHC (p), WB   100 μg Log in to see 4 to 6 Days
$240.00
Details
Bat Rabbit Un-conjugated IHC (p) Anti-ADAMTS4 antibody  ABIN1048291 IHC staining of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated WB Anti-ADAMTS4 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2: Mouse Brain Tissue Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded human lung carcinoma labeled with Anti-ADAMTS4 Polyclonal Antibody, Unconjugated (ABIN755173) at 1:200 followed by conjugation to the secondary antibody and DAB staining. 100 μL Log in to see 3 to 7 Days
$295.90
Details
Bat Rabbit Un-conjugated IHC (p) Human Heart (formalin-fixed, paraffin-embedded) stained with ADAMTS4 antibody ABIN625840 at 12 ug/ml followed by biotinylated goat anti-rabbit IgG secondary antibody ABIN481713, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Mouse Rabbit Un-conjugated WB ADAMTS4 Polyclonal Antibody 0.1 mg Log in to see 6 to 8 Days
$313.50
Details

ADAMTS4 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Antibodies

  1. Cow (Bovine) Polyclonal ADAMTS4 Primary Antibody for IHC, WB - ABIN2776877 : Lee, Hwang, Park, Lee, Park, Kang, Lee, Kim, Park, Park: Comparison of ADAMTS-1, -4 and -5 expression in culprit plaques between acute myocardial infarction and stable angina. in Journal of clinical pathology 2011 (PubMed)
    Show all 3 Pubmed References

  2. Human Polyclonal ADAMTS4 Primary Antibody for WB - ABIN391642 : Tortorella, Pratta, Liu, Abbaszade, Ross, Burn, Arner: The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 Pubmed References

More Antibodies against ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. the reduction of ADAMTS-4 activity during the progression of ALS pathology may be an adaptive change to mitigate its neurodegenerative impact in CNS tissues

  2. Results show that ADAMTS15 (show ADAMTS15 Antibodies) and ADAMTS4 not only exhibit unique cellular expression patterns in the brain but their developmental upregulation by these cell types coincides with critical aspects of neural development

  3. aggrecan (show ACAN Antibodies) and brevican (show BCAN Antibodies) proteolysis is compensated in Adamts4-/- or Adamts5 (show ADAMTS5 Antibodies)-/- mice by ADAMTS (show ADAMTS1 Antibodies) proteoglycanase (show MMP3 Antibodies) family members but a threshold of versican (show Vcan Antibodies) proteolysis is sensitive to the loss of a single ADAMTS (show ADAMTS1 Antibodies) proteoglycanase (show MMP3 Antibodies) during spinal cord injury

  4. ADAMTS4 has roles in melanoma growth and angiogenesis in mice

  5. The serine protease (show F2 Antibodies) tissue plasminogen activator (tPA (show PLAT Antibodies)) and two matrix metalloproteinases, ADAMTS-4 and ADAMTS-5 (show ADAMTS5 Antibodies), were identified as Reelin (show RELN Antibodies) cleaving enzymes.

  6. ADAMTS-4 cleaves Reelin (show RELN Antibodies) in an isoform-specific manner. Among ADAMTS-4 isoforms, p50 (show LSP1 Antibodies) cleaves the N-t site only, while p75 (show NGFR Antibodies) cleaves both sites.

  7. Data demonstrate that Adamts1 (show ADAMTS1 Antibodies) and Adamts4 play redundant and essential roles in perinatal kidney development.

  8. Drastic down-regulation of Adamts4 observed at both E16 (show SLC7A5 Antibodies) and E18; RT-PCR revealed post-natal reduction in expression (Adamts4, 1/3). Results suggest down-regulation of gene is important factor in normal odontogenesis in dental papillae.

  9. proteolysis of hevin by ADAMTS4 in the mouse cerebellum is important for the normal development of this tissue

  10. ADAMTS1 (show ADAMTS1 Antibodies), ADAMTS4, and ADAMTS5 (show ADAMTS5 Antibodies) are expressed in patterns that relate to the expression pattern of versican (show Vcan Antibodies) in granulosa cells of small follicles, expanded cumulus cell-oocyte complexes, and endothelial cells of the ovary.

Human ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Using in vitro approaches and cultured breast cancer cell lines authors demonstrate that Fibulin-2 (show FBLN2 Antibodies) is a better substrate for ADAMTS-5 (show ADAMTS5 Antibodies) than it is for ADAMTS-4. Fibulin-2 (show FBLN2 Antibodies) degradation is associated to an enhancement of the invasive potential of T47D, MCF-7 and SK-BR-3 cells.

  2. ADAMTS4 and ADAMTS15 (show ADAMTS15 Antibodies) were upregulated in symptomatic uterine leiomyomas.

  3. The SNP rs4233367 in the exon of ADAMTS-4 gene may be associated with lumbar disc degeneration.

  4. Single Nucleotide Variants of Candidate Genes in Aggrecan (show ACAN Antibodies) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  5. Results show that ADAMTS4 mRNA is the target of mir (show MLXIP Antibodies)-1268a and its expression might be modified by MIR (show MLXIP Antibodies)-1268a rs28599926 polymorphism in hepatocellular carcinoma.

  6. The pregnancy loss rate seems to be affected by both ADAMTS-3 and ADAMTS-16 (show ADAMTS16 Antibodies).

  7. we investigated whether important polymorphisms in the ADAMTS4 and ADAMTS5 (show ADAMTS5 Antibodies) genes affect osteoarthritis (OA) susceptibility. ADAMTS4 and ADAMTS5 (show ADAMTS5 Antibodies) genotypes were determined using the ABI Prism StepOnePlus Real-Time system. Our findings suggest that the ADAMTS4 (rs4233367 and rs11807350) and ADAMTS5 (show ADAMTS5 Antibodies) (rs226794 and rs2830585) variants examined may not contribute to susceptibility to knee OA in the Turkish population.

  8. ADAMTS4 expression is significantly upregulated in human masticatory mucosa during wound healing

  9. ADAMTS4 may have a role in the pathogenesis by causing increased oxidative and inflammatory environment in preterm premature rupture of membranes .

  10. in degenerative intervertebral discs, IL1b (show IL1B Antibodies) upregulates NFkB, MMP13 (show MMP13 Antibodies) and ADAMTS4

Horse (Equine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. Studies suggest that miR (show MYLIP Antibodies)-140 is an important regulator of cartilage development and homeostasis in cord blood-derived mesenchymal stromal cells (eCB-MSCs) that may act, in part, through the regulation of CXCL12 (show CXCL12 Antibodies) and ADAMTS-5 (show ADAMTS5 Antibodies).

  2. ADAMTS5 (show ADAMTS5 Antibodies) is present in degenerative suspensory ligament desmitis as a high molecular weight complex

Rabbit ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. a single injection of ADAMTS5 (show ADAMTS5 Antibodies) siRNA induced the suppression of degradation in rabbit nucleus pulposus tissues

Cow (Bovine) ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) interaction partners

  1. ADAMTS4 participates in the regulation of muscle development in cattle.

  2. aggrecanase activity (a) is responsible for early TNFalpha (show TNF Antibodies)-dependent aggrecan (show ACAN Antibodies) cleavage and GAG release in the meniscus and (b) might be involved in meniscal degeneration.

  3. ADAMTS4 and ADAMTS5 (show ADAMTS5 Antibodies) are inhibited by alpha2-macroglobulin (show A2M Antibodies)

  4. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 and ADAMTS-5 (show ADAMTS5 Antibodies)

ADAM Metallopeptidase with Thrombospondin Type 1 Motif, 4 (ADAMTS4) Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The protein encoded by this gene is the major procollagen II N-propeptidase. A deficiency of this protein may be responsible for dermatosparaxis, a genetic defect of connective tissues.

Gene names and symbols associated with ADAMTS4

  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 (Adamts4) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (ADAMTS4) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 13 (ADAMTS13) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) (ADAMTS5) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 4 (Adamts4) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (Adamts19) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 19 (ADAMTS19) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 3 (ADAMTS3) antibody
  • aggrecanase-1 (ADAMTS-4) antibody
  • ADAMTS-like 4 (ADAMTSL4) antibody
  • 3830423K05 antibody
  • ADAM-TS4 antibody
  • ADAMTS-2 antibody
  • ADAMTS-4 antibody
  • ADAMTS-11 antibody
  • ADAMTS4 antibody
  • ADAMTS5 antibody
  • ADAMTS13 antibody
  • ADMP-1 antibody
  • DKFZp469J0817 antibody
  • mKIAA0688 antibody

Protein level used designations for ADAMTS4

A disintegrin and metalloproteinase with thrombospondin motifs 4 , ADAM-TS 4 , ADAMTS-4 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 4 , aggrecanase-1 , ADAM-TS4 , ADAM metallopeptidase with thrombospondin type 1 motif, 13 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 13 , ADAM metallopeptidase with thrombospondin type 1 motif, 5 , ADAM metallopeptidase with thrombospondin type 1 motif, 5 (aggrecanase-2) , aggrecanase-2 , Aggrecanase , a disintegrin and metallopeptidase with thrombospondin motifs 4 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 4 , ADMP-1 , ADAM metallopeptidase with thrombospondin type 1 motif, 4 , A disintegrin and metalloproteinase with thrombospondin motifs 4-like , A disintegrin and metalloproteinase with thrombospondin motifs 19 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 19 , ADAM metallopeptidase with thrombospondin type 1 motif, 19-like , A disintegrin and metalloproteinase with thrombospondin motifs 3 , ADAM-TS 3 , ADAM-TS3 , ADAMTS-3 , PC II-NP , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 3 , procollagen II N-proteinase , procollagen II amino propeptide-processing enzyme , zinc metalloendopeptidase , disintegrin and metalloproteinase with thrombospondin motifs 2

GENE ID SPECIES
240913 Mus musculus
9507 Homo sapiens
417152 Gallus gallus
473153 Pan troglodytes
487713 Canis lupus familiaris
427971 Gallus gallus
100066005 Equus caballus
100008799 Oryctolagus cuniculus
707672 Macaca mulatta
473935 Pan troglodytes
66015 Rattus norvegicus
286806 Bos taurus
457453 Pan troglodytes
488651 Canis lupus familiaris
719927 Macaca mulatta
100033914 Equus caballus
100171426 Pongo abelii
100409334 Callithrix jacchus
361332 Rattus norvegicus
415600 Gallus gallus
462039 Pan troglodytes
537961 Bos taurus
705362 Macaca mulatta
9508 Homo sapiens
100008765 Oryctolagus cuniculus
100482466 Ailuropoda melanoleuca
100606067 Nomascus leucogenys
100514576 Sus scrofa
100712995 Cavia porcellus
101106565 Ovis aries
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