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ADAM Metallopeptidase with thrombospondin Type 1 Motif, 12 Proteins (ADAMTS12)

ADAMTS12 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Additionally we are shipping ADAMTS12 Kits (23) and ADAMTS12 Antibodies (22) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ADAMTS12 239337 Q811B3
ADAMTS12 81792 P58397
Rat ADAMTS12 ADAMTS12 294809  
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Top ADAMTS12 Proteins at antibodies-online.com

Showing 7 out of 9 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag 100 μg Log in to see 11 to 13 Days
$806.30
Details
HOST_Escherichia coli (E. coli) Human His tag 100 μg Log in to see 11 to 13 Days
$704.00
Details
HOST_Wheat germ Human GST tag 2 μg Log in to see 9 Days
$333.33
Details
HOST_Escherichia coli (E. coli) Human Un-conjugated   100 μg Log in to see 9 to 19 Days
$889.07
Details
HOST_Escherichia coli (E. coli) Mouse Un-conjugated   100 μg Log in to see 9 to 19 Days
$983.48
Details

ADAMTS12 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,
,

More Proteins for ADAM Metallopeptidase with thrombospondin Type 1 Motif, 12 (ADAMTS12) Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 12 (ADAMTS12) interaction partners

  1. ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review]

  2. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis.

  3. ADAMTS-12 plays protective roles acting against the development of asthma phenotype upon experimental allergen exposure, interfering with immunological processes leading to inflammation and airway hyperresponsiveness.

  4. Results define a break point in mouse chromosome 15qA1 to a 27-kb region containing ADAMTS12, and show that the break is likely between exons 2 and 3 of ADAMTS12.

  5. Absence of Adamts-12 is associated with the increase in angiogenic response and tumor invasion into host tissue.

Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 12 (ADAMTS12) interaction partners

  1. ADAMTS-12 is a multifaced metalloproteinase in arthritis and inflammation [review]

  2. ADAMTS-12 is implicated in the inflammatory response by modulating normal neutrophil apoptosis.

  3. Our results suggest that ADAMTS12 may be a susceptibility gene for RA development.

  4. statistically significant increase in mRNA expression of ADAMTS-7 (show ADAMTS7 Proteins) and ADAMTS-12 was observed in the endplate cells in degenerative discs compared with nondegenerative discs

  5. The data supported the hypothesis that genetic variations in ADAMTS12 influence the risk of schizophrenia.

  6. expression of ADAMTS12 in colorectal cancer stroma plays an important role in inhibiting tumor development

  7. This study identifies a novel biological role for ADAMTS-12, and highlights the importance and complexity of its non-proteolytic domain(s) pertaining to its function.

  8. ADAMTS-12 is a new COMP (show COMP Proteins)-interacting and -degrading enzyme and thus may play an important role in the COMP (show COMP Proteins) degradation in the initiation and progression of arthritis

  9. data suggest that ADAMTS12 confers tumour-protective functions upon cells that produce this proteolytic enzyme

  10. ADAMTS-7 (show ADAMTS7 Proteins) and ADAMTS-12 are newly identified enzymes responsible for cartilage oligomeric matrix protein (show COMP Proteins) degradation in arthritis.

ADAMTS12 Protein Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS-1) motif. Individual members of this family differ in the number of C-terminal TS-1 motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains eight TS-1 motifs. It may play roles in pulmonary cells during fetal development or in tumor processes through its proteolytic activity or as a molecule potentially involved in regulation of cell adhesion.

Gene names and symbols associated with ADAMTS12

  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (ADAMTS12)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (adamts12)
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12 (Adamts12)
  • ADAM metallopeptidase with thrombospondin type 1 motif, 12 (Adamts12)
  • adam-ts12 protein
  • ADAMTS-12 protein
  • AI605170 protein
  • PRO4389 protein

Protein level used designations for ADAMTS12

ADAM metallopeptidase with thrombospondin type 1 motif, 12 , adam-ts 12 , A disintegrin and metalloproteinase with thrombospondin motifs 12 , ADAM-TS 12 , ADAM-TS12 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 12 , a disintegrin-like and metalloprotease with thrombospondin type 1 motif, 12 , metalloprotease disintegrin 12 , ADAMTS-12 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 12

GENE ID SPECIES
100351077 Oryctolagus cuniculus
100380018 Xenopus (Silurana) tropicalis
100394926 Callithrix jacchus
100453667 Pongo abelii
100463655 Ailuropoda melanoleuca
100511353 Sus scrofa
100605835 Nomascus leucogenys
239337 Mus musculus
81792 Homo sapiens
294809 Rattus norvegicus
101118642 Ovis aries
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