anti-ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) Antibodies

ADAMTS5 encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Additionally we are shipping ADAMTS5 Kits (36) and ADAMTS5 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ADAMTS5 23794 Q9R001
ADAMTS5 11096 Q9UNA0
ADAMTS5 304135  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top anti-ADAMTS5 Antibodies at antibodies-online.com

Showing 10 out of 115 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, WB Western blot analysis of anti-ADAMTS5 Antibody (Center) in mouse muscle tissue lysates (35ug/lane). ADAMTS5(arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Mouse Rabbit Un-conjugated WB Western blot analysis of anti-ADAMTS5 Antibody (Center) (ABIN391652) in mouse muscle tissue lysates (35 µg/lane). ADAMTS5(arrow) was detected using the purified polyclonal antibody. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ADAMTS5 antibody, IHC(P) IHC(P): Rat Brain Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated WB ADAMTS5 Antibody (N-term) (ABIN657768) western blot analysis in K562 cell line lysates (35 µg/lane). This demonstrates the ADAMTS5 antibody detected the ADAMTS5 protein (arrow). 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB IHC-P Image Immunohistochemical analysis of paraffin-embedded A549 xenograft, using ADAMTS5, antibody at 1:100 dilution. WB Image Sample (30 ug of whole cell lysate) A: JC 7.5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 1 to 2 Days
$358.60
Details
Human Rabbit Un-conjugated WB   100 μg Log in to see 4 to 6 Days
$357.50
Details
Human Rabbit Un-conjugated IHC, IHC (p), WB Immunohistochemistry-Paraffin: ADAMTS5 Antibody [NBP2-15286] - Paraffin-embedded Hepatoma, using antibody at 1:500 dilution. Western Blot: ADAMTS5 Antibody [NBP2-15286] - Sample (30 ug of whole cell lysate) A: HeLa B: HepG2 7. 5% SDS PAGE, antibody diluted at 1:3000. 0.1 mL Log in to see 8 to 11 Days
$447.56
Details
Bat Rabbit Un-conjugated IHC (p) Anti-ADAMTS5 antibody  ABIN1048295 IHC staining of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Human Rabbit Un-conjugated IHC (p) Anti-ADAMTS5 antibody  ABIN1048296 IHC staining of human cartilage. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details
Hamster Rabbit Un-conjugated IHC (p) Anti-ADAMTS5 antibody  ABIN1048293 IHC staining of human placenta. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. 50 μg Log in to see 7 to 9 Days
$451.00
Details

ADAMTS5 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
Mouse (Murine) , , ,


, , , , , , , , , , , , , , , ,
Human , , , ,
, ,
,
, , , , , , , , , , , , , , , ,
Rat (Rattus) , , ,


, , , , , , , , , , , , ,

Top referenced anti-ADAMTS5 Antibodies

  1. Human Polyclonal ADAMTS5 Primary Antibody for EIA, WB - ABIN359611 : Abbaszade, Liu, Yang, Rosenfeld, Ross, Link, Ellis, Tortorella, Pratta, Hollis, Wynn, Duke, George, Hillman, Murphy, Wiswall, Copeland, Decicco, Bruckner, Nagase, Itoh, Newton, Magolda, Trzaskos, Burn: Cloning and characterization of ADAMTS11, an aggrecanase from the ADAMTS family. in The Journal of biological chemistry 1999 (PubMed)
    Show all 2 references for 359611

  2. Mouse (Murine) Polyclonal ADAMTS5 Primary Antibody for WB - ABIN391652 : Tortorella, Pratta, Liu, Abbaszade, Ross, Burn, Arner: The thrombospondin motif of aggrecanase-1 (ADAMTS-4) is critical for aggrecan substrate recognition and cleavage. in The Journal of biological chemistry 2000 (PubMed)
    Show all 2 references for 391652

More Antibodies against ADAMTS5 Interaction Partners

Mouse (Murine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) interaction partners

  1. research emphasises the importance of ADAMTS5 expression in the control of influenza virus infection and highlights the potential for development of ADAMTS5-based therapeutic strategies to reduce morbidity and mortality

  2. TS5 protein functions to suppress glucose uptake in adipose-derived stromal cells and thereby inhibits the synthesis, and promotes the intracellular degradation of Acan (show ACAN Antibodies) and Vcan (show Vcan Antibodies) by an ADAMTS (show ADAMTS1 Antibodies) other than TS5.

  3. Data suggest that ADAMTS-5 oligomerization is required for full aggrecanase (show ADAMTS4 Antibodies) activity in vitro and in situ (as seen in knee joint of mouse model of inflammatory arthritis); thus, blocking oligomerization inhibits ADAMTS-5 activity.

  4. aggrecan (show ACAN Antibodies) and brevican (show BCAN Antibodies) proteolysis is compensated in Adamts4 (show ADAMTS4 Antibodies)-/- or Adamts5-/- mice by ADAMTS (show ADAMTS1 Antibodies) proteoglycanase (show MMP3 Antibodies) family members but a threshold of versican (show Vcan Antibodies) proteolysis is sensitive to the loss of a single ADAMTS (show ADAMTS1 Antibodies) proteoglycanase (show MMP3 Antibodies) during spinal cord injury

  5. The present study reveals ADAMT-5 expression by mast cells(MCs (show SMCP Antibodies)) and that MC activation regulates the expression of the protease, thus implicating the ADAMT-5 of protease in MC function.

  6. Western blot analyses indicated that aggrecanase (show ADAMTS4 Antibodies)-generated proteoglycan (show Vcan Antibodies) fragments are produced after SCI.

  7. RelA/p65 (show NFkBP65 Antibodies) is a potent transcriptional activator of ADAMTS5 in chondrocytes during osteoarthritis development.

  8. Repair of biomechanically compromised tendons exhibiting midsubstance chondroid accumulation requires ADAMTS5.

  9. this study identified, for the first time, several genes that have an ADAMTS-5-independent role in osteoarthritis(OA), identifying them as possible OA initiation candidates.

  10. The serine protease (show F2 Antibodies) tissue plasminogen activator (tPA (show PLAT Antibodies)) and two matrix metalloproteinases, ADAMTS-4 (show ADAMTS4 Antibodies) and ADAMTS-5, were identified as Reelin (show RELN Antibodies) cleaving enzymes.

Human ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) interaction partners

  1. Endoplasmic reticulum stress participates in the progress of senescence and apoptosis of osteoarthritic chondrocytes, which manifested in increased expression of ADAMTS5, MMP13 (show MMP13 Antibodies), and decreased COL2A1 (show COL2A1 Antibodies) expression.

  2. Single Nucleotide Variants of Candidate Genes in Aggrecan (show ACAN Antibodies) Metabolic Pathway Are Associated with Lumbar Disc Degeneration and Modic Changes

  3. RREB1 (show RREB1 Antibodies) cooperates with noncoding RNA linc-ADAMTS5 to inhibit ADAMTS5 expression, thereby affecting degeneration of the extracellular matrix (ECM (show MMRN1 Antibodies)) of the intervertebral disc.

  4. Matrilin 2 (show MATN2 Antibodies) accumulation associated with relative ADAMTS5 deficiency may contribute to the mechanism underlying calcific aortic valve disease progression.

  5. In osteoarthritis (OA) chondrocytes, hydrostatic pressure (HP) restores the expression levels of some miRNAs, downregulates MMP-13 (show MMP13 Antibodies), ADAMTS-5, and HDAC-4 (show HDAC4 Antibodies), and modulates the Wnt (show WNT2 Antibodies)/beta-catenin (show CTNNB1 Antibodies) pathway activation.

  6. we investigated whether important polymorphisms in the ADAMTS4 (show ADAMTS4 Antibodies) and ADAMTS5 genes affect osteoarthritis (OA) susceptibility. ADAMTS4 (show ADAMTS4 Antibodies) and ADAMTS5 genotypes were determined using the ABI Prism StepOnePlus Real-Time system. Our findings suggest that the ADAMTS4 (show ADAMTS4 Antibodies) (rs4233367 and rs11807350) and ADAMTS5 (rs226794 and rs2830585) variants examined may not contribute to susceptibility to knee OA in the Turkish population.

  7. Increased ADAMTS5 levels were observed in placental insufficiency cases.

  8. ADAMTS5 protein levels in semen were significantly lower in males with infertility. Sperm count and motility showed a negative correlation with levels of ADAMTS5 protein expression.

  9. Overexpression of ADAMTS5 is associated with migration and invasion of non-small cell lung cancer.

  10. ADAMTS5 rs2380585 polymorphism contributes to hepatocellular carcinoma susceptibility in a Chinese Han population

Cow (Bovine) ADAM Metallopeptidase with thrombospondin Type 1 Motif, 5 (ADAMTS5) interaction partners

  1. The delayed activation of proMMPs and the relatively low cleavage efficiency of MMPs compared to ADAMTS5 (aggrecanase (show ADAMTS4 Antibodies)) explains the minor contribution of the MMP enzymes to aggrecan (show ACAN Antibodies) catabolism in vivo.

  2. ADAMTS4 (show ADAMTS4 Antibodies) and ADAMTS5 are inhibited by alpha2-macroglobulin (show A2M Antibodies)

  3. identified multiple conserved amino acids within regions N- and C-terminal to the site of scission that may influence enzyme-substrate recognition, and may interact with exosites on ADAMTS-4 (show ADAMTS4 Antibodies) and ADAMTS-5

  4. Co-culture of mechanically injured cartilage with joint capsule tissue alters chondrocyte expression patterns and increases ADAMTS5 production.

ADAMTS5 Antigen Profile

Protein Summary

This gene encodes a member of the ADAMTS (a disintegrin and metalloproteinase with thrombospondin motifs) protein family. Members of the family share several distinct protein modules, including a propeptide region, a metalloproteinase domain, a disintegrin-like domain, and a thrombospondin type 1 (TS) motif. Individual members of this family differ in the number of C-terminal TS motifs, and some have unique C-terminal domains. The enzyme encoded by this gene contains two C-terminal TS motifs and functions as aggrecanase to cleave aggrecan, a major proteoglycan of cartilage.

Gene names and symbols associated with ADAMTS5

  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (ADAMTS5) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (adamts5) antibody
  • a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) (Adamts5) antibody
  • ADAM metallopeptidase with thrombospondin type 1 motif, 5 (Adamts5) antibody
  • 9530092O11Rik antibody
  • ADAM-TS5 antibody
  • ADAM-TS 5 antibody
  • ADAM-TS 11 antibody
  • ADAMTS-5 antibody
  • ADAMTS-11 antibody
  • ADAMTS1 antibody
  • ADAMTS11 antibody
  • ADMP-2 antibody
  • AI481094 antibody
  • ASMP-2 antibody

Protein level used designations for ADAMTS5

ADAM metallopeptidase with thrombospondin type 1 motif, 5 , a disintegrin and metalloproteinase with thrombospondin motifs 5-like , A disintegrin and metalloproteinase with thrombospondin motifs 5 , ADAM-TS 5 , ADAMTS-5 , ADMP-2 , aggrecanase-2 , implantin , a disintegrin and metalloproteinase with thrombospondin motifs 11 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2) , ADAM-TS5 , a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 5 , a disintegrin-like and metallopeptidase (reprolysin type) with thrombospondin type 1 motif, 5 (aggrecanase-2)

GENE ID SPECIES
100091913 Ornithorhynchus anatinus
100441162 Pongo abelii
100488158 Xenopus (Silurana) tropicalis
100552915 Anolis carolinensis
23794 Mus musculus
11096 Homo sapiens
100522952 Sus scrofa
286805 Bos taurus
304135 Rattus norvegicus
Selected quality suppliers for anti-ADAMTS5 (ADAMTS5) Antibodies
Did you look for something else?