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ADPGK (EC 188.8.131.52) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004 [PubMed 14975750]).[supplied by OMIM, Mar 2008].. Additionally we are shipping ADPGK Antibodies (42) and ADPGK Proteins (6) and many more products for this protein.
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ADPGK is substrate inhibited by high glucose concentration and shows high specificity for glucose, with no activity for other sugars, as determined by NMR spectroscopy, including 2-deoxyglucose
ADPGK can contribute to tumour cell survival under conditions of high glycolytic dependence.
human ADPGK(ADP-dependent glucokinase) catalyses ADP-dependent phosphorylation of glucose in vitro, but despite its high expression in human tumour cell lines it appears not to make a quantifiable contribution to glycolysis under the conditions evaluated.
Glucose and insulin (show INS ELISA Kits) response to oral glucose is higher in GCK (show GCK ELISA Kits)(261) carriers, indicating clinical heterogeneity in GCK (show GCK ELISA Kits) maturity diabetes carriers.
The presence of mild persistent hyperglycemia in any patient without autoantibodies should lead to genetic analysis of glucokinase (show GCK ELISA Kits), particularly if there is a positive family history.
Results suggest that sterol regulatory-element binding protein (show CNBP ELISA Kits)-1c is unlikely to be the mediator of the early insulin (show INS ELISA Kits) effect on glucokinase (show GCK ELISA Kits) gene transcription.
ADPGK (EC 184.108.40.206) catalyzes the ADP-dependent phosphorylation of glucose to glucose-6-phosphate and may play a role in glycolysis, possibly during ischemic conditions (Ronimus and Morgan, 2004
, ADP-dependent glucokinase