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The protein encoded by ARF6 is a GTPase-activating protein (GAP) which associates with the Golgi apparatus and which interacts with ADP-ribosylation factor 1 (ARF1). Additionally we are shipping ADP-Ribosylation Factor 6 Kits (16) and ADP-Ribosylation Factor 6 Proteins (14) and many more products for this protein.
Showing 10 out of 78 products:
Human Monoclonal ARF6 Primary Antibody for WB - ABIN180609
Yang, Heimberg, DSouza-Schorey, Mueckler, Stahl: Subcellular distribution and differential expression of endogenous ADP-ribosylation factor 6 in mammalian cells. in The Journal of biological chemistry 1998
Show all 2 references for ABIN180609
Chicken Polyclonal ARF6 Primary Antibody for IHC, WB - ABIN2785790
Karim, Choi, Whiteheart: Primary platelet signaling cascades and integrin-mediated signaling control ADP-ribosylation factor (Arf) 6-GTP levels during platelet activation and aggregation. in The Journal of biological chemistry 2008
We show that Arf6 functions in the adult nervous system to control ethanol-induced behavior.
Cindr-mediated regulation of Arf6 is a widely used mechanism in emerging epithelia.
ARF6 promotes rapid recycling of endosomal membrane stores during spermatocyte cytokinesis, which is critical for rapid cleavage furrow ingression.
results provide evidence for a novel Arf6 activation mechanism by Dyn2 (show DNM2 Antibodies) through EFA6B (show PSD4 Antibodies) and EFA6D (show PSD3 Antibodies) in CME in a manner dependent upon the GTPase (show RACGAP1 Antibodies) activity of Dyn2 (show DNM2 Antibodies)
Mutant p53 (show TP53 Antibodies), which is known to support tumorigenesis via MVP (show MVP Antibodies), promotes Arf6 activation.
The expression of miR (show MLXIP Antibodies)-206 by HUVECs reduced exosome production by regulating ADP-Ribosylation Factor 6 (ARF6) and sodium/calcium exchanger 1 (NCX1 (show SLC8A1 Antibodies)).
The role of EGFR (show EGFR Antibodies)-ARF6 signaling in BA.
Data suggest ADAP2 (show ADAP2 Antibodies) (an interferon-beta (show IFNB1 Antibodies) stimulated gene) disrupts pathogenic internalization of some RNA viruses/virions (dengue, vesicular stomatitis) by altering ADP ribosylation factor 6-mediated processes including up-regulation of pinocytosis.
A dominant negative mutant of Arf6 blocks direct transport of APP (show APP Antibodies) to lysosomes, but does not affect classical endocytosis to endosomes.
Results show that miR (show MLXIP Antibodies)-145 directly targets the 3'UTR (show UTS2R Antibodies) of ARF6 mRNA; its expression is upregulated in triple-negative breast cancer and tumor metastasis.
The authors show that Shigella flexneri IpgD phosphatase activity is required for recruitment of the ARF6 guanine nucleotide exchange factor (show RASGRF1 Antibodies) (GEF (show SLC2A4RG Antibodies)) ARF nucleotide binding site opener (ARNO (show CYTH2 Antibodies)) to bacterial entry sites.
a role for ARF6 in linking EGF-receptor signaling to Rac1 recruitment and activation at the plasma membrane to promote breast cancer cell directed migration
Wnt5a is a potential suppressor of EMT; there is a novel Arf6/ERK signaling pathway for EGF-regulated Wnt5a expression at transcriptional level of gastric cancer cel
In platelet-specific Arf6 knockout mice,Arf6 KO platelets had less associated Fg suggesting that Arf6 affects alphaIIbbeta3-mediated Fg uptake and/or storage. They were also defective in FITC-Fg uptake and storage.
findings show for the first time that Ang II (show AGT Antibodies) receptor signaling to beta-arrestin regulates ARF6 activation. These proteins together control receptor endocytosis and ultimately cell migration.
The role of ARF-6 and Annexin A2 (show ANXA2 Antibodies) in the invasion of mammalian cells by T. cruzi amastigotes.
Findings demonstrate that Arf6 in neurons of the CNS plays an important role in oligodendrocyte precursor cells migration by regulating secretion of FGF-2 (show FGF2 Antibodies) from neurons, thereby contributing to the axon myelination.
RLIP76 regulates Arf6-dependent cell spreading and migration by linking ARNO with activated R-Ras at recycling endosomes.
Arf6 is required for hepatocyte growth factor (HGF (show HGF Antibodies))-induced tumour neoangiogenesis and growth.
the activation-inactivation cycles of Rab35 (show RAB35 Antibodies) and ARF6 are required for the uptake of zymosan and that ACAP2 (show ACAP2 Antibodies) is an important component that links Rab35 (show RAB35 Antibodies)/ARF6 signaling during phagocytosis of zymosan.
Arf6 plays an important role in oligodendrocyte precursor cells migration through regulation of FGF-2 (show FGF2 Antibodies) secretion during neuronal development.
These results suggest that signaling through Arf6 is required for Schwann cell myelination, adding Arf6 to the list of intracellular signaling molecules involved in the myelination process.
results together suggest that cytohesin 2 (show CYTH2 Antibodies) activates ARF6 in a PI3K dependent manner and then the active ARF6 causes phosphorylation of ERK1/2 (show MAPK1/3 Antibodies) during preadipocyte migration.
Pparg pathway acts on cephalic neural crest to direct adipocyte differentiation at the expense of osteoblast formation
PPAR (show PPARA Antibodies) expression, the activity of its target gene AOX (show ACOX1 Antibodies), and peroxisomal biogenesis are developmentally modulated in zebrafish
This gene encodes a member of the human ARF gene family, which is part of the RAS superfamily. The ARF genes encode small guanine nucleotide-binding proteins that stimulate the ADP-ribosyltransferase activity of cholera toxin and play a role in vesicular trafficking and as activators of phospholipase D. The product of this gene is localized to the plasma membrane, and regulates vesicular trafficking, remodelling of membrane lipids, and signaling pathways that lead to actin remodeling. A pseudogene of this gene is located on chromosome 7.
ADP ribosylation factor III
, ADP-ribosylation factor 6
, peroxisome proliferator-activated receptor gamma