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ADP-Ribosylation Factor Related Protein 1 Proteins (ARFRP1)

The protein encoded by ARFRP1 is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. Additionally we are shipping ARFRP1 Antibodies (26) and ARFRP1 Kits (17) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ARFRP1 10139 Q13795
ARFRP1 76688 Q8BXL7
Rat ARFRP1 ARFRP1 117051 Q63055
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Top ARFRP1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Cow His tag   1 mg Log in to see 56 to 66 Days
$2,489.67
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

ARFRP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
,
Mouse (Murine)

More Proteins for ADP-Ribosylation Factor Related Protein 1 (ARFRP1) Interaction Partners

Human ADP-Ribosylation Factor Related Protein 1 (ARFRP1) interaction partners

  1. One or more of 7 genes residing in a chromosome 20q13.3 CNV region appears to influence BMI. The strongest candidate is ARFRP1.

  2. Propose that Arfrp1 exposes a binding site on AP-1 (show FOSB Proteins) that recognizes the Vangl2 (show VANGL2 Proteins) sorting motif for capture into a transport vesicle destined for the proximal surface of a polarized epithelial cell.

  3. The GTPase (show RACGAP1 Proteins) ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium.

  4. Data show that ADP-ribosylation factor-related protein 1 (ARFRP1) is associated mainly with the trans-Golgi compartment and the trans-Golgi network (TGN (show TG Proteins)) and is an essential regulatory factor for targeting of golgin-97 (show GOLGA1 Proteins) and golgin-245 onto Golgi membranes.

  5. These data suggest that lethality of Arfrp1 knockout embryos is due to a specific disruption of protein targeting, e.g., of ARL1 and Golgin-245, to the Golgi.

  6. Results show that ARL1 and ARFRP1 regulate retrograde transport of Shiga toxin to the TGN (show TG Proteins) and anterograde transport of VSVG from the TGN (show TG Proteins), respectively.

Mouse (Murine) ADP-Ribosylation Factor Related Protein 1 (ARFRP1) interaction partners

  1. ARFRP1 and the Golgi apparatus play an important role in lipoprotein maturation in the liver.

  2. The GTPase (show RACGAP1 Proteins) ARFRP1 controls the lipidation of chylomicrons in the Golgi of the intestinal epithelium.

  3. data indicate that ARFRP1 in the liver is involved in the regulation of IGF1 (show IGF1 Proteins) secretion and GLUT2 (show SLC2A2 Proteins) sorting and is thereby essential for normal growth and glycogen (show GYS1 Proteins) storage

  4. Arfrp1 appears to be involved in sorting of GLUT4 (show SLC2A4 Proteins).

  5. Lipid droplets of adipocytes of Arfrp1(-/-) mice were smaller and exhibited ultrastructural alterations, such as a disturbed interaction of small lipid particles with larger droplets.

  6. ADP-ribosylation factor (show ARF1 Proteins)-like GTPase (show RACGAP1 Proteins) ARFRP1 is required for trans-Golgi to plasma membrane trafficking of E-cadherin (show CDH1 Proteins).

  7. This study provides the first detailed analysis of the regional distribution of ARFRP1 in the mouse brain and a quantitative view of its changes following sleep deprivation.

Cow (Bovine) ADP-Ribosylation Factor Related Protein 1 (ARFRP1) interaction partners

  1. These data suggest that lethality of Arfrp1 knockout embryos is due to a specific disruption of protein targeting, e.g., of ARL1 and Golgin-245, to the Golgi.

ARFRP1 Protein Profile

Protein Summary

The protein encoded by this gene is a membrane-associated GTP-ase which localizes to the plasma membrane and is related to the ADP-ribosylation factor (ARF) and ARF-like (ARL) proteins. This gene plays a role in membrane trafficking between the trans-Golgi network and endosomes. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene names and symbols associated with ARFRP1

  • ADP-ribosylation factor related protein 1 (arfrp1)
  • ADP-ribosylation factor related protein 1 (ARFRP1)
  • ADP-ribosylation factor related protein 1 (Arfrp1)
  • 1500006I01Rik protein
  • AI480700 protein
  • ARFRP1 protein
  • ARL18 protein
  • ARP protein
  • Arp1 protein
  • MGC75956 protein
  • zgc:113118 protein

Protein level used designations for ARFRP1

ADP-ribosylation factor related protein 1 , ADP-ribosylation factor-related protein 1 , putative ADP-ribosylation factor related protein 1 variant 1 , ARF-related protein 1 , SCG10 like-protein , helicase-like protein NHL , ARP

GENE ID SPECIES
394772 Xenopus (Silurana) tropicalis
419261 Gallus gallus
503602 Danio rerio
695611 Macaca mulatta
740068 Pan troglodytes
100190101 Taeniopygia guttata
100302308 Ovis aries
100444340 Pongo abelii
10139 Homo sapiens
76688 Mus musculus
117051 Rattus norvegicus
525394 Bos taurus
612540 Canis lupus familiaris
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