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anti-ADP-Ribosylation Factor-Like 13B (ARL13B) Antibodies

ARL13B encodes a member of the ADP-ribosylation factor-like family. Additionally we are shipping ARL13B Kits (11) and ARL13B Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ARL13B 304037  
ARL13B 200894 Q3SXY8
ARL13B 68146 Q640N2
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Top anti-ARL13B Antibodies at antibodies-online.com

Showing 10 out of 21 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ARL13B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: 721_B cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ARL13B Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:1562500Positive Control: Jurkat cell lysate WB Suggested Anti-ARL13B  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:1562500  Positive Control: Jurkat cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated ELISA, WB 50 μg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB Human Jurkat; WB Suggested Anti-ARL13B Antibody Titration: 0.2-1 ug/ml. ELISA Titer: 1:1562500. Positive Control: Jurkat cell lysate; ARL13B antibody - middle region in Human Jurkat cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Mouse Un-conjugated ELISA, WB Western Blot detection against Immunogen (36.74 KDa) . 200 μL Log in to see 9 Days
$430.00
Details
Human Rabbit Un-conjugated WB ARL13B antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Un-conjugated IF, WB   100 μL Log in to see 14 Days
$527.15
Details
Human Rabbit Un-conjugated ELISA   100 μL Log in to see 8 to 10 Days
$390.50
Details
Human Rabbit Un-conjugated IF, ELISA, WB   50 μL Log in to see 9 to 11 Days
$313.50
Details

ARL13B Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Rat (Rattus)


Human ,
,
,
Mouse (Murine)


Top referenced anti-ARL13B Antibodies

  1. Human Polyclonal ARL13B Primary Antibody for WB - ABIN2785090 : Fan, Esmail, Ansley, Blacque, Boroevich, Ross, Moore, Badano, May-Simera, Compton, Green, Lewis, van Haelst, Parfrey, Baillie, Beales, Katsanis, Davidson, Leroux: Mutations in a member of the Ras superfamily of small GTP-binding proteins causes Bardet-Biedl syndrome. in Nature genetics 2004 (PubMed)
    Show all 2 references for ABIN2785090

More Antibodies against ARL13B Interaction Partners

Zebrafish ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. Arl13b is an important effector of ciliary membrane biogenesis and ciliary length regulation.

  2. Cilia localization is essential for in vivo functions of the Joubert syndrome protein arl13b.

Human ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. Thus our data identify a novel ARL13B variant that causes JS and retinopathy and suggest an extension of the phenotypic spectrum of ARL13B mutations to obesity.

  2. We conclude that MKS/NPHP modules comprise a TZ barrier to ARL-13 diffusion, whereas IFT genes predominantly facilitate ARL-13 ciliary entry and/or retention via active transport mechanisms.

  3. X-ray crystallography of Arl13B demonstrates involvement of mutations R79Q and R200C in stabilizing intramolecular interactions.

  4. Arl13b acts as the all-rounder in cilia formation and signaling (Review).

  5. findings indicate that ARL13B, INPP5E, PDE6D (show PDE6D Antibodies), and CEP164 (show CEP164 Antibodies) form a distinct functional network that is involved in JBTS and NPHP but independent of the ones previously defined by NPHP and MKS (show MKS1 Antibodies) proteins

  6. data reveal a novel but conserved role for the SUMOylation modification of ciliary small GTPase (show RACGAP1 Antibodies) ARL13B in specifically regulating the proper ciliary targeting of various sensory receptors

  7. These results indicate a previously unidentified role for Arl13b in endocytic recycling traffic and suggest a link between Arl13b function and the actin cytoskeleton.

  8. Expression of Arl13b variants known to cause Joubert syndrome induce defective interneuronal migration, suggesting that defects in cilia-dependent interneuron migration may in part underlie the neurological defects in Joubert syndrome patients.

  9. data implicate a role for JS-associated Arl13b at ciliary membranes, where it regulates ciliary transmembrane protein localizations and anterograde IFT assembly stability

  10. These findings suggest that N and C domains of Arl13b cooperatively regulate its ciliary localization and that N domain-dependent self-association of Arl13b may be important for its function in cilia biogenesis.

Mouse (Murine) ADP-Ribosylation Factor-Like 13B (ARL13B) interaction partners

  1. The authors show that the ciliary G-protein Arl13B, mutated in Joubert syndrome, is the guanine nucleotide exchange factor for Arl3, and its function is conserved in evolution

  2. A new role for Arl13b in actin cytoskeleton remodeling through the interaction with Myh9 (show MYH9 Antibodies).

  3. Early neuroepithelial deletion of ciliary Arl13b reversed the apical-basal polarity of radial progenitors & caused aberrant neuronal placement. Arl13b signaling in primary cilia is crucial for initial formation of a polarized radial glial scaffold.

  4. guidance cue receptors essential for interneuronal migration localize to interneuronal primary cilia, but their concentration and dynamics are altered in the absence of Arl13b

  5. By deleting Arl13b in mouse, we induced low-level constitutive GliA function at specific developmental stages and defined a crucial period prior to E10.5 when shifts in the level of GliA cause cells to change their fate

  6. Study shows the cilia protein Arl13b is required for left right axis specification as its absence results in heterotaxia; the defect originates in the node where Cerl2 (show DAND5 Antibodies) is not downregulated and asymmetric expression of Nodal is not maintained resulting in symmetric expression of both genes.

  7. The role of Arl13b in ciliogenesis and it's interaction with Smo and Shh (show SHH Antibodies) proteins.Arl13b regulates the ciliary entry of Smo.

  8. Arl13bhnn mutants have abnormal ventral neural tube patterning due to disrupted sonic hedgehog signaling; in addition, dorsal patterning defects occur from abnormal bone morphogenetic protein signaling.

ARL13B Antigen Profile

Protein Summary

This gene encodes a member of the ADP-ribosylation factor-like family. The encoded protein is a small GTPase that contains both N-terminal and C-terminal guanine nucleotide-binding motifs. This protein is localized in the cilia and plays a role in cilia formation and in maintenance of cilia. Mutations in this gene are the cause of Joubert syndrome 8. Alternate splicing results in multiple transcript variants.

Gene names and symbols associated with ARL13B

  • ADP-ribosylation factor-like 13B (Arl13b) antibody
  • ADP-ribosylation factor-like 13B (ARL13B) antibody
  • ADP-ribosylation factor-like 13B (arl13b) antibody
  • ADP-ribosylation factor-like 13b (arl13b) antibody
  • A530097K21Rik antibody
  • A930014M17Rik antibody
  • Arl2l1 antibody
  • C530009C10Rik antibody
  • chunp6872 antibody
  • fc23g07 antibody
  • hnn antibody
  • JBTS8 antibody
  • MGC185757 antibody
  • wu:fc23g07 antibody
  • zgc:123149 antibody

Protein level used designations for ARL13B

ADP-ribosylation factor-like protein 13B , ADP-ribosylation factor-like 2-like 1 , ADP-ribosylation factor-like 13B , ADP-ribosylation factor-like protein 13B-like , ADP-ribosylation factor-like protein 2-like 1 , ARL2-like protein 1 , protein scorpion , scorpion , un-named hi459 , unm hi459

GENE ID SPECIES
304037 Rattus norvegicus
418431 Gallus gallus
460534 Pan troglodytes
487934 Canis lupus familiaris
512781 Bos taurus
694959 Macaca mulatta
100124913 Xenopus (Silurana) tropicalis
100413286 Callithrix jacchus
100456801 Pongo abelii
100467626 Ailuropoda melanoleuca
100600917 Nomascus leucogenys
286784 Danio rerio
200894 Homo sapiens
68146 Mus musculus
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