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ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs\\\\; see MIM 103180). Additionally we are shipping ADP-Ribosylation Factor-Like 5B Antibodies (21) and ADP-Ribosylation Factor-Like 5B Proteins (6) and many more products for this protein.
Arl5b is a trans-golgi-network-localised small G protein (show RAC2 ELISA Kits) that plays a key role in regulating transport along the endosome-trans-golgi network pathway
Arl8 and SKIP are required for lysosomes to distribute away from the microtubule-organizing center. We identify two kinesin light chain binding motifs in SKIP that are required for lysosomes to accumulate kinesin-1 and redistribute to the cell periphery.
ARL8 contains six exons and five introns, and encodes a 179 amino acid protein that shares homology to the other ARL proteins.
Our results, therefore, suggest that Arl5B is a negative regulator for MDA5 (show IFIH1 ELISA Kits).
The expression pattern of the mouse ortholog Arl8 revealed differential tissue expression and an alternate transcript was seen in brain that was age-dependent.
ARL5B (ARL8) belongs to a family of proteins that are structurally similar to ADP-ribosylation factors (ARFs\; see MIM 103180). ARLs and ARFs are part of the RAS superfamily of regulatory GTPases.
ADP-ribosylation factor-like 8
, ADP-ribosylation factor-like 5B
, ADP-ribosylation factor-like protein 5B
, ADP-ribosylation factor-like protein 8
, ADP-ribosylation-like factor 8