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ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Additionally we are shipping ART1 Antibodies (50) and ART1 Proteins (4) and many more products for this protein.
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Our data suggest that ART1 could regulate EMT (show ITK ELISA Kits) by regulating the RhoA (show RHOA ELISA Kits)/ROCK1 (show ROCK1 ELISA Kits)/AKT (show AKT1 ELISA Kits)/beta-catenin (show CTNNB1 ELISA Kits) pathway and its downstream factors (snail1 (show SNAI1 ELISA Kits), vimentin (show VIM ELISA Kits), N-cadherin (show CDH2 ELISA Kits) and E-cadherin (show CDH1 ELISA Kits)) and that it therefore plays an important role in the progression of colon carcinoma.
up-regulation of ART1 expression is associated with the aggressiveness of glioma.
Arginine ADP-ribosyltransferase 1 promotes angiogenesis in c (show HIF1A ELISA Kits)olorectal ca (show AKT1 ELISA Kits)ncer via the PI3K/Akt pathway
The altered function and expression of P2X7 (show P2RX7 ELISA Kits) and ART1 in the human CD39 (show ENTPD1 ELISA Kits)+ Treg or CD39 (show ENTPD1 ELISA Kits)- Treg cells could participate in the resistance against cell death induced by ATP or NAD.
This study provides evidence that ARTC1 is activated during the endoplasmic-reticulum stress response, which results in acute ADP-ribosylation of GRP78/BiP (show HSPA5 ELISA Kits) paralleling translational inhibition.
ADP-ribosylation of HNP-1 (show DEFA1 ELISA Kits) appears to be primarily an activity of ART1 and occurs in inflammatory conditions and disease
ADPRT (show PARP1 ELISA Kits) Ala762Val polymorphism may play a role in the etiology of squamous cell carcinoma of the head and neck or in linkage disequilibrium with other untyped protective alleles.
data suggest that ART1 promoted the expression of HIF-1alpha (show HIF1A ELISA Kits) via the Akt (show AKT1 ELISA Kits) pathway in tumor cells.
the apoptosis rate in the ART1-cDNA CT26 cells treated with PARP-1 inhibitor 5-aminoisoquinoline (5-AIQ) and cisplatin increased, when compared with the ART1-cDNA CT26 cells treated with cisplatin only or the untreated ART1-cDNA CT26 cells.
ART1 knockdown reduced survival rate correlated with reduced levels of phos-Akt (show AKT1 ELISA Kits)(Thr308) and phos-IkappaBalpha (show NFKBIA ELISA Kits) and reduced NF-kappaB (show NFKB1 ELISA Kits) p65 (show NFkBP65 ELISA Kits) nuclear translocation.
Successive amino- or carboxyl-terminal truncations of ART1, an arginine-specific transferase, identified regions that regulated transferase and NAD glycohydrolase activities.
ADP-ribosyltransferase catalyzes the ADP-ribosylation of arginine residues in proteins. Mono-ADP-ribosylation is a posttranslational modification of proteins that is interfered with by a variety of bacterial toxins including cholera, pertussis, and heat-labile enterotoxins of E. coli. The amino acid sequence consists of predominantly hydrophobic N- and C-terminal regions, which is characteristic of glycosylphosphatidylinositol (GPI)-anchored proteins. This gene was previously designated ART2.
, ADP-ribosyltransferase 1
, ADP-ribosyltransferase 2
, ADP-ribosyltransferase C2 and C3 toxin-like 1
, GPI-linked NAD(P)(+)--arginine ADP-ribosyltransferase 1
, mono(ADP-ribosyl)transferase 1
, NAD:arginine ADP-ribosyltransferase