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AE Binding Protein 1 Proteins (AEBP1)

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. Additionally we are shipping AEBP1 Antibodies (38) and AEBP1 Kits (11) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AEBP1 165 Q8IUX7
AEBP1 11568 Q640N1
Rat AEBP1 AEBP1 305494 A2RUV9
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Top AEBP1 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 49 to 54 Days
$13,567.94
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details

AEBP1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for AE Binding Protein 1 (AEBP1) Interaction Partners

Human AE Binding Protein 1 (AEBP1) interaction partners

  1. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA (show SMN1 Proteins) expression via TGFbeta (show TGFB1 Proteins) signaling and promoting collagen expression through a TGFbeta (show TGFB1 Proteins) receptor-independent pathway.

  2. There is no statistically significant differences in the frequency of variants in AEBP1 among the gastroschisis case group compared to a Caucasian control group.

  3. Most ACLP knockout mice die perinatally due to abdominal issues.

  4. Both cellular proliferation and survival were affected in AEBP1-silenced U87MG and U138MG cell lines and a significant percentage of these cells were directed towards apoptosis.

  5. This review focuses on the recently reported regulatory functions that adipocyte enhancer-binding protein 1 (AEBP1) exerts on PPARgamma1 and LXRalpha (show NR1H3 Proteins) transcriptional activity in the context of macrophage cholesterol homeostasis and inflammation.

  6. Transgenic overexpression of AEBP1 during adipogenesis coupled with a high-fat diet results in massive obesity in female transgenic mice via adipocyte hyperplasia.

  7. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

Mouse (Murine) AE Binding Protein 1 (AEBP1) interaction partners

  1. ACLP stimulates the fibroblast-to-myofibroblast transition by promoting SMA (show SMN1 Proteins) expression via TGFbeta (show TGFB1 Proteins) signaling and promoting collagen expression through a TGFbeta (show TGFB1 Proteins) receptor-independent pathway.

  2. Stromal adipocyte enhancer-binding protein (AEBP1) promotes mammary epithelial cell hyperplasia via proinflammatory and hedgehog (show SHH Proteins) signaling

  3. Data suggest that macrophage AEBP1 plays critical regulatory roles in atherogenesis, and it may serve as a potential therapeutic target for the prevention or treatment of atherosclerosis.

  4. Results describe the pathophysiological features of gastroschisis in aortic carboxypeptidase-like protein knockout mice and to characterize the neuromuscular development of the eviscerated intestine.

  5. MAPK (show MAPK1 Proteins) regulates the transcriptional activity of AEBP1 by a novel dual mechanism, in which MAPK (show MAPK1 Proteins) interaction enhances and subsequent phosphorylation decreases the DNA-binding ability of AEBP1

  6. AEBP1 plays critical regulatory roles in macrophage cholesterol homeostasis, foam cell formation, and proinflammation.

  7. NF-kappaB (show NFKB1 Proteins) activity is modulated by means of protein-protein interaction involving AEBP1 and IkappaBalpha (show NFKBIA Proteins).

  8. AEBP1 negatively regulates adipose tissue PTEN levels and has a key functional role in modulation of in vivo adiposity.

  9. Adipocyte enhancer-binding protein 1 (AEBP1) is up-regulated during monocyte differentiation.

  10. ACLP and its discoidin-like domain may be novel targets for anti-myofibroblast-based therapies for the treatment of pulmonary fibrosis.

AEBP1 Protein Profile

Protein Summary

The adipocyte enhancer binding protein 1 is a transcriptional repressor with carboxypeptidase (CP) activity. This protein binds to a regulatory sequence, adipocyte enhancer 1 (AE-1), located in the proximal promoter region of the adipose P2 (aP2) gene, which encodes the adipocyte fatty-acid binding protein. It is characterized as a member of the regulatory B-like CP family. This protein seems to be activated by a novel mechanism, whereby the direct binding of DNA enhances its protease activity. Adipocyte-enhancer binding protein 1 may play a role in differentiated vascular smooth muscle cells.

Gene names and symbols associated with AE Binding Protein 1 Proteins (AEBP1)

  • AE binding protein 1 (Closa_4071)
  • AE binding protein 1 (AEBP1)
  • AE binding protein 1 (Aebp1)
  • ACLP protein

Protein level used designations for AE Binding Protein 1 Proteins (AEBP1)

AE binding protein 1 , adipocyte enhancer-binding protein 1 , aortic carboxypeptidase-like protein , AE-binding protein 1

GENE ID SPECIES
9509393 Clostridium saccharolyticum WM1
165 Homo sapiens
733628 Sus scrofa
11568 Mus musculus
305494 Rattus norvegicus
317693 Bos taurus
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