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The specific function of ALX1 has yet to be determined in humans\; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Additionally we are shipping ALX1 Proteins (5) and many more products for this protein.
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we identify critical roles of ALX1 in lung cancer development and progression
Knockdown of the CART1 gene significantly inhibited cell invasion and proliferation and induce cell cycle arrest in S phase.
we found that depletion of ALX1 caused a dramatic cell cycle arrest, followed by massive apoptotic cell death, and eventually resulted in a significant decrease in migration and invasion of the osteosarcoma cell line studied.
hypermethylation of HIST1H4F, PCDHGB6 (show PCDHgB6 Antibodies), NPBWR1 (show NPBWR1 Antibodies), ALX1, and HOXA9 (show HOXA9 Antibodies) was significantly associated with shorter survival in stage 1 Non-small-cell lung cancer
ALX1 upregulated expression of the key EMT (show ITK Antibodies) regulator Snail (SNAI1 (show SNAI1 Antibodies)) and that it mediated EMT (show ITK Antibodies) activation and cell invasion by ALX1.
Disruption of CART1 (ALX1) causes extreme microphthalmia and severe facial clefting.
Scapula development is governed by genetic interactions of Pbx1 (show PBX1 Antibodies) with its family members and with Emx2 (show EMX2 Antibodies) via their cooperative control of Alx1
We now demonstrate the function of the aristaless domain in vivo by ectopically expressing normal and mutated forms of Cart1 (show TRAF4 Antibodies) and Alx3 (show ALX3 Antibodies)
p300/CBP (show CREBBP Antibodies) stimulate Cart1 (show TRAF4 Antibodies)-dependent transcription activity, and this transactivation is inhibited by E1A (show BCKDHA Antibodies) and Tax (show CNTN2 Antibodies), oncoproteins that suppress the activity of p300/CBP (show CREBBP Antibodies)
The specific function of this gene has yet to be determined in humans\; however, in rodents, it is necessary for survival of the forebrain mesenchyme and may also be involved in development of the cervix. Mutations in the mouse gene lead to neural tube defects such as acrania and meroanencephaly.
ALX homeobox 1
, cartilage paired-class homeoprotein 1
, ALX homeobox protein 1
, ALX homeobox protein 1-like
, cartilage homeo protein 1
, cartilage homeoprotein 1