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anti-APC Membrane Recruitment Protein 1 (AMER1) Antibodies

The protein encoded by AMER1 upregulates trancriptional activation by the Wilms tumor protein and interacts with many other proteins, including CTNNB1, APC, AXIN1, and AXIN2. Additionally we are shipping APC Membrane Recruitment Protein 1 Kits (2) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
AMER1 72345 Q7TS75
AMER1 139285 Q5JTC6
AMER1 501584  
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Top anti-APC Membrane Recruitment Protein 1 Antibodies at antibodies-online.com

Showing 10 out of 38 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated FACS, IHC (p), WB Western blot analysis of WTX antibody (Center) (ABIN390467) in mouse kidney tissue lysates (35 µg/lane). WTX (arrow) was detected using the purified polyclonal antibody. WTX Antibody (Center) (ABIN390467) IHC analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Western blot analysis of WTX antibody (Center) in mouse kidney tissue lysates (35ug/lane). WTX (arrow) was detected using the purified Pab. 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated WB   100 μL Log in to see 8 to 10 Days
$683.83
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 555 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 647 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 488 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

AMER1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-APC Membrane Recruitment Protein 1 Antibodies

  1. Human Polyclonal AMER1 Primary Antibody for FACS, IHC (p) - ABIN390467 : Rivera, Kim, Wells, Stone, Burger, Coffman, Zhang, Haber: The tumor suppressor WTX shuttles to the nucleus and modulates WT1 activity. in Proceedings of the National Academy of Sciences of the United States of America 2009 (PubMed)
    Show all 2 references for ABIN390467

  2. Human Polyclonal AMER1 Primary Antibody for EIA, IHC (p) - ABIN453469 : Fukuzawa, Anaka, Weeks, Morison, Reeve: Canonical WNT signalling determines lineage specificity in Wilms tumour. in Oncogene 2009 (PubMed)
    Show all 2 references for ABIN453469

More Antibodies against APC Membrane Recruitment Protein 1 Interaction Partners

Mouse (Murine) APC Membrane Recruitment Protein 1 (AMER1) interaction partners

  1. WTX stabilized chromatin binding by TRIM28 (show TRIM28 Antibodies) and contributed to transcriptional repression of repetitive sequences by TRIM28 (show TRIM28 Antibodies) in mouse embryonic stem cells.

  2. The constellation of anomalies in Wtx null mice suggests that this tumor suppressor broadly regulates mesenchymal progenitor cells in multiple tissues.

  3. The observed phenotypic discordance dependent upon whether a mutation is germline or occurs somatically suggests the existence of temporal or spatial constraints on the action of WTX during tumorigenesis.

Human APC Membrane Recruitment Protein 1 (AMER1) interaction partners

  1. Losses of AMER1 by other mechanisms apart from mutations.

  2. A nonsense mutation (c.1045C>T, p.Glu349*) in the WTX gene.

  3. Data show that beta-arrestins regulate Wnt3a (show WNT3A Antibodies)-induced low density lipoprotein receptor-related protein 6 (Lrp6 (show LRP6 Antibodies)) phosphorylation by the regulation of the membrane dynamics of Amer1.

  4. WTX inactivation occurs in a wider variety of tumor types than previously appreciated and point to shared pathogenic mechanisms between a subset of pediatric malignancies.

  5. Data indicate that osteopathia striata congenita with cranial sclerosis (OSCS) iscaused by germline deletions of in the X-linked gene WTX (FAM123B, AMER1).

  6. Two novel WTX mutations underscore the unpredictability of male survival in osteopathia striata with cranial sclerosis.

  7. Stat3 (show STAT3 Antibodies) inhibits WTX expression through up-regulation of micro RNA-370 in Wilms tumor.

  8. Osteopathia striata with cranial sclerosis or Horan-Beighton syndrome is a rare X-linked dominant inherited bone dysplasia. Genetic analysis allowed the identification of maternally transmitted heterozygous nonsense c.1057C>T (p.R353X) WTX mutation.

  9. WTX mutations occur early in Wilms' tumor development, but at a low proportion. There was no evidence that WTX is the main cause of Wilms' tumor.

  10. WTX modulates p53 (show TP53 Antibodies) function, in part through regulation of its activator CBP/p300 (show CREBBP Antibodies).

APC Membrane Recruitment Protein 1 (AMER1) Antigen Profile

Protein Summary

The protein encoded by this gene upregulates trancriptional activation by the Wilms tumor protein and interacts with many other proteins, including CTNNB1, APC, AXIN1, and AXIN2. Defects in this gene are a cause of osteopathia striata with cranial sclerosis (OSCS).

Gene names and symbols associated with AMER1

  • APC membrane recruitment 1 (Amer1) antibody
  • APC membrane recruitment protein 1 (AMER1) antibody
  • APC membrane recruitment protein 1 (Amer1) antibody
  • APC membrane recruitment protein 1 (amer1) antibody
  • family with sequence similarity 123B (FAM123B) antibody
  • 2810002O09Rik antibody
  • AW492303 antibody
  • fam123b antibody
  • OSCS antibody
  • RGD1560322 antibody
  • WTX antibody

Protein level used designations for AMER1

APC membrane recruitment protein 1 , family with sequence similarity 123, member B , protein Fam123b , Wilms tumor gene on the X chromosome protein , Wilms tumor on the X , adenomatous polyposis coli membrane recruitment 1 , family with sequence similarity 123B , protein FAM123B , APC membrane recruitment 1 , Protein FAM123B , wtx

GENE ID SPECIES
72345 Mus musculus
139285 Homo sapiens
501584 Rattus norvegicus
100885784 Danio rerio
422314 Gallus gallus
539029 Bos taurus
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