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APC Membrane Recruitment Protein 2 Proteins (AMER2)

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Additionally we are shipping AMER2 Kits (3) and and many more products for this protein.

list all proteins Gene Name GeneID UniProt
AMER2 72125 Q8CCJ4
AMER2 219287 Q8N7J2
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Top AMER2 Proteins at antibodies-online.com

Showing 3 out of 3 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 39 to 44 Days
$9,248.02
Details
HOST_Human Human Un-conjugated   20 μg Log in to see 9 to 11 Days
$785.40
Details

AMER2 Proteins by Origin and Source

Origin Expressed in Conjugate
Mouse (Murine)

Human ,

More Proteins for APC Membrane Recruitment Protein 2 (AMER2) Interaction Partners

Mouse (Murine) APC Membrane Recruitment Protein 2 (AMER2) interaction partners

  1. the Amer2-EB1 (show MAPRE1 Proteins)-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.

Human APC Membrane Recruitment Protein 2 (AMER2) interaction partners

  1. FAM123A binds to microtubules and inhibits the guanine nucleotide exchange factor (show RASGRF1 Proteins) ARHGEF2 (show ARHGEF2 Proteins) to decrease actomyosin contractility.

  2. the Amer2-EB1 (show MAPRE2 Proteins)-APC (show APC Proteins) complex regulates cell migration by altering microtubule stability.

  3. data characterize Amer2 for the first time as a negative regulator of Wnt (show WNT2 Proteins) signaling both in cell lines and in vivo and define Amer proteins as a novel family of Wnt (show WNT2 Proteins) pathway regulators.

AMER2 Protein Profile

Protein Summary

Negative regulator of the canonical Wnt signaling pathway involved in neuroectodermal patterning. Acts by specifically binding phosphatidylinositol 4,5-bisphosphate (PtdIns(4,5)P2), translocating to the cell membrane and interacting with key regulators of the canonical Wnt signaling pathway, such as components of the beta-catenin destruction complex (By similarity).

Gene names and symbols associated with AMER2

  • APC membrane recruitment 2 (Amer2)
  • APC membrane recruitment protein 2 (AMER2)
  • APC membrane recruitment protein 2 (amer2)
  • family with sequence similarity 123A (FAM123A)
  • 2600011E07Rik protein
  • fam123a protein
  • zgc:165647 protein

Protein level used designations for AMER2

APC membrane recruitment protein 2 , family with sequence similarity 123, member A , protein FAM123A , family with sequence similarity 123A , amer2

GENE ID SPECIES
72125 Mus musculus
219287 Homo sapiens
100101649 Danio rerio
418939 Gallus gallus
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