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APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004 [PubMed 15262985]).[supplied by OMIM, Dec 2008].. Additionally we are shipping APIP Proteins (15) and many more products for this protein.
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Human Polyclonal APIP Primary Antibody for WB - ABIN2786905
Cho, Hong, Lee, Woo, Pyo, Mak, Jung: Induced inhibition of ischemic/hypoxic injury by APIP, a novel Apaf-1-interacting protein. in The Journal of biological chemistry 2004
APIP/MtnB functions as a cell death inhibitor independently of its MtnB enzyme activity for apoptosis induced by either hypoxia or etoposide, but dependently for caspase-1 (show CASP1 Antibodies)-induced pyroptosis
these results confirm the involvement of APIP in the methionine salvage pathway, which plays a key role in many biological functions like cancer, apoptosis, microbial proliferation and inflammation.
human APIP was overproduced in Escherichia coli, purified and crystallized. An X-ray diffraction data set was collected to 2.40 A resolution
A polymorphism associated with reduced expression of a putative methionine salvage pathway dehydratase, apoptotic protease activating factor 1 (APAF1 (show APAF1 Antibodies))-interacting protein (APIP), was associated with increased caspase-1 (show CASP1 Antibodies)-mediated cell death in Salmonella.
The down-regulation of APIP and UACA (show UACA Antibodies) expression suggests that the threshold to activate the apoptosome apparatus may be decreased in non-small cell lung cancer cells.
APIP functions to inhibit muscle ischemic damage by binding to Apaf-1 (show APAF1 Antibodies) in the Apaf-1 (show APAF1 Antibodies)/caspase-9 (show CASP9 Antibodies) apoptosis pathway.
APIP is an APAF1 (MIM 602233)-interacting protein that acts as a negative regulator of ischemic/hypoxic injury (Cho et al., 2004
, MTRu-1-P dehydratase
, methylthioribulose-1-phosphate dehydratase
, probable methylthioribulose-1-phosphate dehydratase
, monocyte macrophage 19
, monocyte/macrophage protein 19
, APAF1-interacting protein homolog
, putative methylthioribulose-1-phosphate dehydratase
, Probable methylthioribulose-1-phosphate dehydratase