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Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A. Additionally we are shipping ARP6 Actin-Related Protein 6 Homolog (Yeast) Proteins (7) and many more products for this protein.
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Human Polyclonal ACTR6 Primary Antibody for WB - ABIN657810
Lamesch, Li, Milstein, Fan, Hao, Szabo, Hu, Venkatesan, Bethel, Martin, Rogers, Lawlor, McLaren, Dricot, Borick, Cusick, Vandenhaute, Dunham, Hill, Vidal: hORFeome v3.1: a resource of human open reading frames representing over 10,000 human genes. in Genomics 2007
Show all 2 references for ABIN657810
Data indicate that mutations in genes for SWR1 (show SRCAP Antibodies) complex subunits photoperiod-independent Early Flowering1 (PIE1), actin-related protein6 (ARP6), and SWR1 (show SRCAP Antibodies) complex6 (SWC6) cause hypersensitivity to various DNA damaging agents.
ARP6 is required for proper H2A.Z (show H2AFZ Antibodies) deposition at a number of Pi starvation response (PSR (show JMJD6 Antibodies)) genes in Arabidopsis. [ARP6]
ARP6 acts in the nucleus to regulate plant development, and it does so through modulation of chromatin structure and the control of gene expression.[AtARP6]
ESD1 encodes ATARP6, a putative component of chromatin remodelling that positively regulates FLC accumulation.
The identification and characterization of SERRATED LEAVES AND EARLY FLOWERING (SEF (show IL17RD Antibodies)) in A. thaliana and its interactions with other proteins, including ATARP6 and PIE1, are reported.
Arabidopsis SWC6 (AtSWC6), SUPPRESSOR OF FRIGIDA 3 (SUF3) and PHOTOPERIOD-INDEPENDENT EARLY FLOWERING 1 (PIE1) are homologs of SWC6, ARP6 and SWR1 (show SRCAP Antibodies) with roles in development, including floral repression through full activation of FLOWERING LOCUS C
under starvation, ARP6 was required for cell survival through the repression of rDNA transcription independently of H2A.Z (show H2AFZ Antibodies)
Results describe the predominant nuclear localization of another Arp (show CRISP1 Antibodies) subfamily, Arp6, in vertebrate cells, and show its colocalization with heterochromatin protein 1 orthologs in pericentric heterochromatin.
Component of the SWR1 complex which mediates the ATP- dependent exchange of histone H2A for the H2A variant H2A.F/Z leading to transcriptional regulation of selected genes (e.g. FLC) by chromatin remodeling. Required for the activation of FLC and FLC/MAF genes expression to levels that inhibit flowering, through both histone H3 and H4 acetylation and methylation mechanisms. Involved in several developmental processes including organization of plant organs, leaves formation, flowering time repression, and fertility. Modulates photoperiod-dependent epidermal leaves cell development\; promotes cell division in long days, and cell expansion/division in short days. May be involved in the regulation of pathogenesis-related proteins (PRs).
ARP6 actin-related protein 6 homolog
, actin-related protein 6