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This locus encodes an AT-rich DNA interacting domain-containing protein. Additionally we are shipping ARID1B Antibodies (37) and and many more products for this protein.
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The patterns of expression of ARID1A (show ARID1A ELISA Kits) and ARID1B genes through various mouse embryonic stages, was examined.
These data suggest that the BAF250B-associated SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) is essential for mouse embryonic stem cells to maintain their normal proliferation and pluripotency.
A subset of mammalian SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complexes, specifically containing ARID1B, is required for efficient cell cycle re-entry and for association of activation factors with the c-myc (show MYC ELISA Kits) promoter.
ARID1B potentially serves as a valuable prognostic and predictive biomarker as well as a therapeutic target in breast cancer.
This study demonstrate that ARID1B is required for neuronal differentiation in the developing brain, such as in dendritic arborization and synapse formation.
De novo mutations in ARID1B associated with both syndromic and non-syndromic short stature
Results show the crystal structure and binding site of SWI1 protein and identify loop L1 and L2 regions of SWI1 ARID likely play key roles in ARID-DNA interactions.
ARID1B role in genome-wide transcriptional regulation by SWI (show SMARCA1 ELISA Kits)/SNF (show SNRPA ELISA Kits) complexes.
This study provide the evidence ARID1B mutation releate to Autism Spectrum Disorder.
Chromatin-Remodeling-Factor (show ASH1L ELISA Kits) ARID1B Represses Wnt (show WNT2 ELISA Kits)/beta-Catenin (show CTNNB1 ELISA Kits) Signaling.
BAF (show BANF1 ELISA Kits) complex gene ARID1B is mutated in Coffin-Siris syndrome patients.
Phenotype of Coffin-Siris syndrome patients with ARID1B mutations
The most prominent and consistent clinical findings in patients with ARID1B haploinsufficiency are developmental delay, speech impairment and intellectual disability.
This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternatively spliced transcript variants encoding different isoforms have been described.
AT rich interactive domain 1B (Swi1 like)
, AT-rich interactive domain-containing protein 1B
, transcription factor 1
, ARID domain-containing protein 1B
, BRG1-associated factor 250b
, BRG1-binding protein ELD/OSA1
, ELD (eyelid)/OSA protein