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anti-ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) Antibodies

The protein encoded by ATG16L1 is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Additionally we are shipping ATG16L1 Kits (8) and ATG16L1 Proteins (6) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ATG16L1 55054 Q676U5
ATG16L1 77040 Q8C0J2
ATG16L1 363278  
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Top anti-ATG16L1 Antibodies at antibodies-online.com

Showing 10 out of 167 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot analysis of anti-Autophagy APG16L Antibody (N-term) (ABIN388541) in Hela cell line lysates (35 µg/lane). APG16L(arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with Autophagy APG16L antibody (N-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IF, IHC (p), WB Western blot of APG16L (L92) Pab (ABIN388542) in mouse brain tissue lysate. Cos7, HEK293, MEF, and Hela cells, left to right, respectively. Data courtesy of Drs. Jiefei Geng and Dan Klionsky, University of Michigan. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Western blot analysis of hAPG16L-K366 (ABIN388543) in NIH-3T3, HepG2, Hela, Jurkat and NCI-H460 cell line lysates (35 µg/lane). APG16L (arrow) was detected using the purified polyclonal antibody. Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with Autophagy APG16L antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated DB Dot blot analysis of Phospho-APG16L-S287 Antibody (ABIN389754) on nitrocellulose membrane.  50 ng of Phospho-peptide or Non Phospho-peptide per dot were adsorbed. Antibody working concentrations are 0.5 µg/mL. 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated EIA, IF, WB AP20063PU-N ATG16 antibody staining of HeLa Cell Lysate by Immunocytochemistry at 2 μg/ml. AP20063PU-N ATG16 antibody staining of HeLa Cell Lysate by Immunofluorescence at 4.75 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Dog Goat Un-conjugated EIA, WB AP31061PU-N ATG16L1 antibody staining of Mouse Brain lysate at 0.1 µg/ml (35µg protein in RIPA buffer). Primary incubation was 1 hour. Detected by chemiluminescence. 0.1 mg Log in to see 6 to 8 Days
$379.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-Fixed, Paraffin-Embedded human colon carcinoma tissue reacted with Autophagy APG16L antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Western blot analysis using Autophagy APG16L Antibody (C-term) in NIH-3T3, HepG2, Hela, Jurkat and NCI-H460 cell line lysates (35 µg/lane). 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated EIA, IHC (p), WB Formalin-fixed and paraffin-embedded human colon carcinoma tissue reacted with Autophagy APG16L Antibody , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. Paraformaldehyde-fixed paraffin-embedded biopsy from patient with confirmed colonic Crohn disease. Slide subjected to a citrate-based antigen retrieval procedure, permeabilized by incubation with 0.1% Triton X-100 in 0.1M PBS) washed three times in PBS and blocked with 0.75% bovine serum albumin in PBS for 20 minutes. Sections subsequently incubated with APG16L primary antibody at a 1/200 dilution in 0.75% BSA for 1 h RT. Data courtesy of J. Hampe, S. Schreiber, P. Rosenstiel et al., Institute for Clinical Molecular Biology and First Department of Medicine, Christian-Albrechts University Kiel, University Hospital Schleswig-Holstein, 24105 Kiel, Germany. 0.4 mL Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated EIA, IF, WB Immunocytochemistry of ATG16 in HeLa cells with this product atG16 antibody at 2 μg/ml. Western blot analysis of ATG16 in HeLa cell lysate with this product atG16 antibody at (A) 0.25 and (B) 0.5 μg/ml. 0.1 mg Log in to see 6 to 8 Days
$401.50
Details
Human Rabbit Un-conjugated WB WB Suggested Anti-ATG16L1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:312500Positive Control: Jurkat cell lysate WB Suggested Anti-ATG16L1  Antibody Titration: 0.2-1 µg/mL ELISA Titer: 1:.12500  Positive Control: Jurkat cell lysate  ATG16L1 is supported by BioGPS gene expression data to be expressed in Jurkat 100 μL Log in to see 2 to 3 Days
$289.00
Details

ATG16L1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATG16L1 Antibodies

  1. Human Polyclonal ATG16L1 Primary Antibody for IF, IHC (p) - ABIN388542 : Baehrecke: Autophagy: dual roles in life and death? in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 10 references for ABIN388542

  2. Human Polyclonal ATG16L1 Primary Antibody for EIA, IHC (p) - ABIN1449612 : Nomura, Uzawa, Yamano, Fushimi, Ishigami, Kouzu, Koike, Siiba, Bukawa, Yokoe, Kubosawa, Tanzawa: Overexpression and altered subcellular localization of autophagy-related 16-like 1 in human oral squamous-cell carcinoma: correlation with lymphovascular invasion and lymph-node metastasis. in Human pathology 2008 (PubMed)
    Show all 8 references for ABIN1449612

  3. Human Polyclonal ATG16L1 Primary Antibody for IHC (p), WB - ABIN388543 : Lum, DeBerardinis, Thompson: Autophagy in metazoans: cell survival in the land of plenty. in Nature reviews. Molecular cell biology 2005 (PubMed)
    Show all 6 references for ABIN388543

  4. Human Polyclonal ATG16L1 Primary Antibody for EIA, IHC (p) - ABIN1449636 : Gao, Kang, Liao, Ding, Gambotto, Watkins, Liu, Stolz, Yin: Biochemical isolation and characterization of the tubulovesicular LC3-positive autophagosomal compartment. in The Journal of biological chemistry 2010 (PubMed)
    Show all 6 references for ABIN1449636

  5. Human Polyclonal ATG16L1 Primary Antibody for EIA, IF - ABIN497988 : Kamada, Funakoshi, Shintani, Nagano, Ohsumi, Ohsumi: Tor-mediated induction of autophagy via an Apg1 protein kinase complex. in The Journal of cell biology 2000 (PubMed)
    Show all 5 references for ABIN497988

  6. Human Polyclonal ATG16L1 Primary Antibody for IF, IHC (p) - ABIN388541 : Greenberg: Degrade or die: a dual function for autophagy in the plant immune response. in Developmental cell 2005 (PubMed)
    Show all 5 references for ABIN388541

  7. Human Polyclonal ATG16L1 Primary Antibody for EIA, IF - ABIN499355 : Gozuacik, Kimchi: Autophagy as a cell death and tumor suppressor mechanism. in Oncogene 2004 (PubMed)
    Show all 4 references for ABIN499355

  8. Human Polyclonal ATG16L1 Primary Antibody for DB - ABIN389754 : Ota, Suzuki, Nishikawa, Otsuki, Sugiyama, Irie, Wakamatsu, Hayashi, Sato, Nagai, Kimura, Makita, Sekine, Obayashi, Nishi, Shibahara, Tanaka, Ishii, Yamamoto, Saito, Kawai, Isono, Nakamura, Nagahari et al.: Complete sequencing and characterization of 21,243 full-length human cDNAs. ... in Nature genetics 2003 (PubMed)

  9. Dog (Canine) Polyclonal ATG16L1 Primary Antibody for EIA, WB - ABIN783914 : Rioux, Xavier, Taylor, Silverberg, Goyette, Huett, Green, Kuballa, Barmada, Datta, Shugart, Griffiths, Targan, Ippoliti, Bernard, Mei, Nicolae, Regueiro, Schumm, Steinhart, Rotter, Duerr, Cho, Daly et al.: Genome-wide association study identifies new susceptibility loci for Crohn disease and implicates autophagy in disease pathogenesis. ... in Nature genetics 2007 (PubMed)

More Antibodies against ATG16L1 Interaction Partners

Human ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. Subjects homozygous for the autophagy-related 16-like protein (ATG16L1) CD-associated gene variant (rs2241880), had low SHIP mRNA expression and activity.

  2. The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon (show IFNA Antibodies).

  3. ATG16L1 as a bona fide physiological CSNK2 and PPP1 substrate, which reveals a novel molecular link from CSNK2 to activation of the autophagy-specific ATG12 (show ATG12 Antibodies)-ATG5 (show ATG5 Antibodies)-ATG16L1 complex and autophagy induction

  4. Knockdown of Atg16L1, a crucial autophagy gene, leads to developmental retention of early-stage cells in various tissues where the differentiation of stem cells is retarded.

  5. Antibacterial autophagy is impaired in CLEC12A (show CLEC12A Antibodies)-deficient cells, and this effect is exacerbated in the presence of the ATG16L1( *)300A risk allele.

  6. ATG16L1 may be used as a biomarker for selecting oral squamous cell carcinoma patients with a more aggressive phenotype.

  7. CNTNAP3 (show CNTNAP3 Antibodies) could upregulate the expression of ATG16L1 and increase autophagy vacuoles

  8. ATG16L1 variant rs2241880 was associated with 38% increase in the risk for Crohn's disease for higher mutational load, whereas IL23R (show IL23R Antibodies) variant rs11209026 decreased the risk by 54% for higher mutational load.

  9. CD patients homozygous for the ATG16L1-T300A risk allele show impaired clearance of pathosymbionts in ileal inflammation indicating that ATG16L1 is essential for effective elimination of pathosymbionts upon inflammation.

  10. genotyped 31 Crohn's disease (CD)-associated genes in 102 Slovenian patients. The strongest association for treatment response defined as decrease in CRP (show CRP Antibodies) levels was found for ATG16L1 SNP rs10210302.

Mouse (Murine) ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. Arg-24 of Atg16L1 is crucial for its interaction with Atg5 (show ATG5 Antibodies) which has implications in the binding of the dimeric complex to Rab33B (show RAB33B Antibodies)

  2. inhibition of IL-1beta (show IL1B Antibodies) signaling abrogates the ATG16L1-dependent protection from Urinary tract infections

  3. A hypomorphic mutation in Atg16L1, a crucial autophagy gene, leads to developmental retention of early-stage cells in various tissues where the differentiation of stem cells is retarded.

  4. findings suggest that the regulatory axis of HIF-1alpha (show HIF1A Antibodies)-miRNA-20a-Atg16l1 might be a critical mechanism for hypoxia-induced osteoclast differentiation

  5. Atg16L1 deficiency leads to an exacerbated graft-versus-host disease in a mouse model of allogeneic hematopoietic stem cell transplantation.

  6. nucleotide-binding oligomerization domain containing 2 (show NOD2 Antibodies) deficiency did not reverse the ATG16L1-deficiency-induced protection from urinary tract infections

  7. Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

  8. Data indicate that human ATG16L1 and mouse autophagy components Atg7 (show ATG7 Antibodies) and Atg16L1 participate in the IFN-gamma-induced (show SAMHD1 Antibodies) recruitment of the immunity-related GTPases to the intracellular pathogen.

  9. An Atg16L1 deficiency alters the intestinal environment to mediate an enhanced immune response that is dependent on monocytic cells.

  10. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection.

ATG16L1 Antigen Profile

Protein Summary

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ATG16L1

  • ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1) antibody
  • ATG16 autophagy related 16-like 1 (atg16l1) antibody
  • APG16 autophagy 16-like (LOC100342723) antibody
  • APG16 autophagy 16-like (LOC100345122) antibody
  • autophagy related 16-like 1 (S. cerevisiae) (ATG16L1) antibody
  • autophagy related 16-like 1 (S. cerevisiae) (Atg16l1) antibody
  • 1500009K01Rik antibody
  • Apg16l antibody
  • atg16 antibody
  • ATG16A antibody
  • Atg16l antibody
  • IBD10 antibody
  • Wdr30 antibody

Protein level used designations for ATG16L1

ATG16 autophagy related 16-like 1 (S. cerevisiae) , APG16 autophagy 16-like , autophagy-related protein 16 , APG16-like 1 , autophagy-related 16-like , ATG16 autophagy related 16-like 1 , autophagy-related protein 16-1-like , autophagy-related protein 16-1 , APG16L beta , WD repeat domain 30 , Atg16L1 gamma , autophagy-related 16-like 1 gamma , autophagy-related 16-like 1

GENE ID SPECIES
460022 Pan troglodytes
550097 Xenopus (Silurana) tropicalis
100049143 Xenopus laevis
100342723 Oryctolagus cuniculus
100345122 Oryctolagus cuniculus
714092 Macaca mulatta
100021305 Monodelphis domestica
100400405 Callithrix jacchus
100463901 Ailuropoda melanoleuca
100549478 Meleagris gallopavo
100599327 Nomascus leucogenys
509587 Bos taurus
55054 Homo sapiens
77040 Mus musculus
363278 Rattus norvegicus
424746 Gallus gallus
477412 Canis lupus familiaris
100462746 Sus scrofa
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