You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) Proteins (ATG16L1)

The protein encoded by ATG16L1 is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Additionally we are shipping ATG16L1 Antibodies (167) and ATG16L1 Kits (8) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATG16L1 55054 Q676U5
ATG16L1 77040 Q8C0J2
Rat ATG16L1 ATG16L1 363278  
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ATG16L1 Proteins at antibodies-online.com

Showing 5 out of 6 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
HOST_Escherichia coli (E. coli) Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Escherichia coli (E. coli) Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 29 to 34 Days
$4,331.68
Details
HOST_Wheat germ Human GST tag 10 μg Log in to see 9 Days
$405.71
Details
Yeast Yeast His tag   1 mg Log in to see 56 to 66 Days
$2,330.17
Details
Yeast Pichia angusta His tag   1 mg Log in to see 56 to 66 Days
$2,449.33
Details

ATG16L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human ,
,
Mouse (Murine)

More Proteins for ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) Interaction Partners

Human ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. Subjects homozygous for the autophagy-related 16-like protein (ATG16L1) CD-associated gene variant (rs2241880), had low SHIP mRNA expression and activity.

  2. The Thr300Ala variant in ATG16L1 is associated with improved survival in human colorectal cancer and enhanced production of type I interferon (show IFNA Proteins).

  3. ATG16L1 as a bona fide physiological CSNK2 and PPP1 substrate, which reveals a novel molecular link from CSNK2 to activation of the autophagy-specific ATG12 (show ATG12 Proteins)-ATG5 (show ATG5 Proteins)-ATG16L1 complex and autophagy induction

  4. Knockdown of Atg16L1, a crucial autophagy gene, leads to developmental retention of early-stage cells in various tissues where the differentiation of stem cells is retarded.

  5. Antibacterial autophagy is impaired in CLEC12A (show CLEC12A Proteins)-deficient cells, and this effect is exacerbated in the presence of the ATG16L1( *)300A risk allele.

  6. ATG16L1 may be used as a biomarker for selecting oral squamous cell carcinoma patients with a more aggressive phenotype.

  7. CNTNAP3 could upregulate the expression of ATG16L1 and increase autophagy vacuoles

  8. ATG16L1 variant rs2241880 was associated with 38% increase in the risk for Crohn's disease for higher mutational load, whereas IL23R (show IL23R Proteins) variant rs11209026 decreased the risk by 54% for higher mutational load.

  9. CD patients homozygous for the ATG16L1-T300A risk allele show impaired clearance of pathosymbionts in ileal inflammation indicating that ATG16L1 is essential for effective elimination of pathosymbionts upon inflammation.

  10. genotyped 31 Crohn's disease (CD)-associated genes in 102 Slovenian patients. The strongest association for treatment response defined as decrease in CRP (show CRP Proteins) levels was found for ATG16L1 SNP rs10210302.

Mouse (Murine) ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. Arg-24 of Atg16L1 is crucial for its interaction with Atg5 (show ATG5 Proteins) which has implications in the binding of the dimeric complex to Rab33B (show RAB33B Proteins)

  2. inhibition of IL-1beta (show IL1B Proteins) signaling abrogates the ATG16L1-dependent protection from Urinary tract infections

  3. A hypomorphic mutation in Atg16L1, a crucial autophagy gene, leads to developmental retention of early-stage cells in various tissues where the differentiation of stem cells is retarded.

  4. findings suggest that the regulatory axis of HIF-1alpha (show HIF1A Proteins)-miRNA-20a-Atg16l1 might be a critical mechanism for hypoxia-induced osteoclast differentiation

  5. Atg16L1 deficiency leads to an exacerbated graft-versus-host disease in a mouse model of allogeneic hematopoietic stem cell transplantation.

  6. nucleotide-binding oligomerization domain containing 2 deficiency did not reverse the ATG16L1-deficiency-induced protection from urinary tract infections

  7. Atg16L1 T300A variant decreases selective autophagy resulting in altered cytokine signaling and decreased antibacterial defense.

  8. Data indicate that human ATG16L1 and mouse autophagy components Atg7 (show ATG7 Proteins) and Atg16L1 participate in the IFN-gamma-induced (show SAMHD1 Proteins) recruitment of the immunity-related GTPases to the intracellular pathogen.

  9. An Atg16L1 deficiency alters the intestinal environment to mediate an enhanced immune response that is dependent on monocytic cells.

  10. Atg16l1 is required for autophagy in intestinal epithelial cells and protection of mice from Salmonella infection.

ATG16L1 Protein Profile

Protein Summary

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ATG16L1

  • ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1)
  • ATG16 autophagy related 16-like 1 (atg16l1)
  • APG16 autophagy 16-like (LOC100342723)
  • APG16 autophagy 16-like (LOC100345122)
  • autophagy related 16-like 1 (S. cerevisiae) (ATG16L1)
  • autophagy related 16-like 1 (S. cerevisiae) (Atg16l1)
  • 1500009K01Rik protein
  • Apg16l protein
  • atg16 protein
  • ATG16A protein
  • Atg16l protein
  • IBD10 protein
  • Wdr30 protein

Protein level used designations for ATG16L1

ATG16 autophagy related 16-like 1 (S. cerevisiae) , APG16 autophagy 16-like , autophagy-related protein 16 , APG16-like 1 , autophagy-related 16-like , ATG16 autophagy related 16-like 1 , autophagy-related protein 16-1-like , autophagy-related protein 16-1 , APG16L beta , WD repeat domain 30 , Atg16L1 gamma , autophagy-related 16-like 1 gamma , autophagy-related 16-like 1

GENE ID SPECIES
460022 Pan troglodytes
550097 Xenopus (Silurana) tropicalis
100049143 Xenopus laevis
100342723 Oryctolagus cuniculus
100345122 Oryctolagus cuniculus
714092 Macaca mulatta
100021305 Monodelphis domestica
100400405 Callithrix jacchus
100463901 Ailuropoda melanoleuca
100549478 Meleagris gallopavo
100599327 Nomascus leucogenys
509587 Bos taurus
55054 Homo sapiens
77040 Mus musculus
363278 Rattus norvegicus
424746 Gallus gallus
477412 Canis lupus familiaris
100462746 Sus scrofa
Selected quality suppliers for ATG16L1 Proteins (ATG16L1)
Did you look for something else?