ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) Proteins (ATG16L1)

The protein encoded by ATG16L1 is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Additionally we are shipping ATG16L1 Antibodies (206) and ATG16L1 Kits (5) and many more products for this protein.

list all proteins Gene Name GeneID UniProt
ATG16L1 55054 Q676U5
ATG16L1 77040 Q8C0J2
Rat ATG16L1 ATG16L1 363278  
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Top ATG16L1 Proteins at antibodies-online.com

Showing 6 out of 8 products:

Catalog No. Origin Source Conjugate Images Quantity Supplier Delivery Price Details
Insect Cells Human His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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Insect Cells Mouse His tag „Crystallography Grade“ protein due to multi-step, protein-specific purification process 1 mg Log in to see 60 Days
$7,759.50
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HOST_Wheat germ Human GST tag 10 μg Log in to see 11 to 12 Days
$405.71
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Yeast Yeast His tag   1 mg Log in to see 60 to 71 Days
$2,330.17
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Yeast Pichia angusta His tag   1 mg Log in to see 60 to 71 Days
$2,449.33
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HOST_Escherichia coli (E. coli) Human GST tag,S tag,His tag   100 μg Log in to see 15 to 18 Days
$704.00
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ATG16L1 Proteins by Origin and Source

Origin Expressed in Conjugate
Human , ,
, , ,
Mouse (Murine)

More Proteins for ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) Interaction Partners

Human ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. the data suggested that genetic variants within the ATG16L1 gene promoter were not a risk factor for sporadic Parkinson's disease development

  2. Polymorphism in ATG16L1 gene is associated withinflammatory bowel disease.

  3. EVA1A interacts with the WD repeats of ATG16L1 through its C-terminal and promotes ATG12 (show ATG12 Proteins)-ATG5 (show ATG5 Proteins)/ATG16L1 complex recruitment to the autophagic membrane and enhances the formation of the autophagosome.

  4. Identified and present structure of the predicted WD40 domain (show DCAF12L2 Proteins) boundaries of the autophagy-related protein 16-1 (ATG16L1).

  5. this study revealed that ATG16L1 deficiency led to alterations in macrophage function that contribute to the severity of Crohn disease

  6. The present results support the hypothesis that Trimethylamine N-oxide may be involved in the pathogenesis of inflammatory bowel disease by impacting ATG16L1-induced autophagy and activating NLRP3 (show NLRP3 Proteins) inflammasome.

  7. MicroRNA-410 regulates autophagy-related gene ATG16L1 expression and enhances chemosensitivity via autophagy inhibition in osteosarcoma.(

  8. we focus on the contributions of the plasma membrane to autophagosome biogenesis governed by ATG16L1 and ATG9A (show ATG9A Proteins) trafficking, and summarize the physiological and pathological implications of this macroautophagy route, from development and stem cell fate to neurodegeneration and cancer.

  9. ATG16L1 T300A Polymorphism is Correlated with Gastric Cancer Susceptibility.

  10. Induction of Anti-TNF (show TNF Proteins) induced macrophages is impaired in donors carrying the T300A risk allele for the ATG16L1 suggesting that an intact autophagy pathway may be important for an optimal response to anti-TNF (show TNF Proteins) therapy in inflammatory bowel disease.

Mouse (Murine) ATG16 Autophagy Related 16-Like 1 (S. Cerevisiae) (ATG16L1) interaction partners

  1. Collectively, these data reveal that miR (show MLXIP Proteins)-20a inhibits autophagic response and promotes BCG (show SLC11A1 Proteins) survival in macrophages by targeting ATG7 (show ATG7 Proteins) and ATG16L1.

  2. this study shows that loss of Atg16l1 in myeloid cells exacerbated murine models of colitis

  3. both TNF-R (show TNFRSF1A Proteins) and nucleotide-binding oligomerization domain stimulation promote ATG16L1 stabilization via IKKalpha (show CHUK Proteins)-dependent phosphorylation of ATG16L1 at Ser278.

  4. defective autophagy in intestinal epithelial cells (IECs) may predispose to crohn disease ileitis via impaired clearance of IRE1alpha (show ERN1 Proteins) aggregates during ER stress at this site.

  5. Selective deletion of Atg16l1 in T cells in mice resulted in spontaneous intestinal inflammation that was characterized by aberrant type 2 responses to dietary and microbiota antigens, and by a loss of Foxp3 (show FOXP3 Proteins)(+) Treg cells.

  6. Arg-24 of Atg16L1 is crucial for its interaction with Atg5 (show ATG5 Proteins) which has implications in the binding of the dimeric complex to Rab33B (show RAB33B Proteins)

  7. inhibition of IL-1beta (show IL1B Proteins) signaling abrogates the ATG16L1-dependent protection from Urinary tract infections

  8. A hypomorphic mutation in Atg16L1, a crucial autophagy gene, leads to developmental retention of early-stage cells in various tissues where the differentiation of stem cells is retarded.

  9. findings suggest that the regulatory axis of HIF-1alpha (show HIF1A Proteins)-miRNA-20a-Atg16l1 might be a critical mechanism for hypoxia-induced osteoclast differentiation

  10. Atg16L1 deficiency leads to an exacerbated graft-versus-host disease in a mouse model of allogeneic hematopoietic stem cell transplantation.

ATG16L1 Protein Profile

Protein Summary

The protein encoded by this gene is part of a large protein complex that is necessary for autophagy, the major process by which intracellular components are targeted to lysosomes for degradation. Defects in this gene are a cause of susceptibility to inflammatory bowel disease type 10 (IBD10). Several transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ATG16L1

  • ATG16 autophagy related 16-like 1 (S. cerevisiae) (ATG16L1)
  • ATG16 autophagy related 16-like 1 (atg16l1)
  • APG16 autophagy 16-like (LOC100342723)
  • APG16 autophagy 16-like (LOC100345122)
  • autophagy related 16-like 1 (S. cerevisiae) (ATG16L1)
  • autophagy related 16-like 1 (S. cerevisiae) (Atg16l1)
  • 1500009K01Rik protein
  • Apg16l protein
  • atg16 protein
  • ATG16A protein
  • Atg16l protein
  • IBD10 protein
  • Wdr30 protein

Protein level used designations for ATG16L1

ATG16 autophagy related 16-like 1 (S. cerevisiae) , APG16 autophagy 16-like , autophagy-related protein 16 , APG16-like 1 , autophagy-related 16-like , ATG16 autophagy related 16-like 1 , autophagy-related protein 16-1-like , autophagy-related protein 16-1 , APG16L beta , WD repeat domain 30 , Atg16L1 gamma , autophagy-related 16-like 1 gamma , autophagy-related 16-like 1

GENE ID SPECIES
460022 Pan troglodytes
550097 Xenopus (Silurana) tropicalis
100049143 Xenopus laevis
100342723 Oryctolagus cuniculus
100345122 Oryctolagus cuniculus
714092 Macaca mulatta
100021305 Monodelphis domestica
100400405 Callithrix jacchus
100463901 Ailuropoda melanoleuca
100549478 Meleagris gallopavo
100599327 Nomascus leucogenys
509587 Bos taurus
55054 Homo sapiens
77040 Mus musculus
363278 Rattus norvegicus
424746 Gallus gallus
477412 Canis lupus familiaris
100462746 Sus scrofa
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