ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) ELISA Kits

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Additionally we are shipping ATG4B Antibodies (180) and ATG4B Proteins (13) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
Anti-Human ATG4B ATG4B 23192 Q9Y4P1
Anti-Mouse ATG4B ATG4B 66615 Q8BGE6
Anti-Rat ATG4B ATG4B 316640  
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More ELISA Kits for ATG4B Interaction Partners

Arabidopsis thaliana ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. These results support the conclusion that CML24 affects autophagy progression through interactions with ATG4.

  2. AtATG4a is catalytically more active and has broad AtATG8 substrate specificity compared with AtATG4b. [ATG4b]

Xenopus laevis ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

Human ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. Our work describes an MST4-ATG4B signaling axis that influences glioblastoma autophagy and malignancy

  2. Data show that ULK1 (show ULK1 ELISA Kits), a protein kinase (show CDK7 ELISA Kits) activated at the autophagosome formation site, phosphorylates human ATG4B on serine 316.

  3. Reporter assay showed that HSF1 (show HSF1 ELISA Kits) increased the transcriptional activity of ATG4B gene promoter, and chromatin immunoprecipitation assay verified that HSF1 (show HSF1 ELISA Kits) bound to the site (-1429 to -1417) in ATG4B gene promoter region.

  4. The structure and regulatory machinery of Atg4b [review]

  5. MIRlet-7i is able to regulate autophagic activity via regulating Atg4B expression, which might contribute to the pathogenesis of pre-eclampsia.

  6. The results have interesting implications that SLC27A4 (show SLC27A4 ELISA Kits)/ATG4B complex might be conducive to the occurrence of autophagy in human cancer cells, which is meaningful investigations toward the aim of developing autophagy-targeting drugs and have significant values in clinical application.

  7. Results demonstrated that upregulation of miR (show MLXIP ELISA Kits)-34a by transfection or demethylation resulted in the enhanced apoptosis and drug sensitivity in prostate cancer cells. ATG4B, directly regulated by miR (show MLXIP ELISA Kits)-34a through AMPK (show PRKAA1 ELISA Kits)/mTOR (show FRAP1 ELISA Kits), was involved in this process.

  8. Purified ATG4B protein interact with LC3B (show MAP1LC3B ELISA Kits) in vitro.

  9. ATG4B independently plays a role as a positive regulator on tumor proliferation and a negative regulator on autophagy in colorectal cancer cells.

  10. This study identifies ATG4B as a potential biomarker for predicting therapeutic response in treatment-naive chronic myeloid leukemia (show BCL11A ELISA Kits) stem/progenitor cells and uncovers ATG4B as a possible drug target in these cells.

Mouse (Murine) ATG4 Autophagy Related 4 Homolog B (S. Cerevisiae) (ATG4B) interaction partners

  1. miR (show MLXIP ELISA Kits)-34a might regulate the autophagic activity and can cause injury in ischemia reperfusion injured renal tubular epithelial cells (RTEC) via targeting Atg4B. Atg4B knockdown inhibited autophagy in RTECs.

  2. the ATG4B protease and autophagy play a crucial role protecting epithelial cells against bleomycin-induced stress and apoptosis

  3. REDD1 (show DDIT4 ELISA Kits)/TXNIP (show TXNIP ELISA Kits) complex expression is sufficient to induce reactive oxygen species, suppress ATG4B activity and activate autophagy.

  4. these findings demonstrate a role for Ser (show SIGLEC1 ELISA Kits)-383 and Ser (show SIGLEC1 ELISA Kits)-392 phosphorylation of ATG4B in control of autophagy.

  5. mTOR (show FRAP1 ELISA Kits) inhibition alleviates Huntington's disease progression by inducing Atg4b-dependent autophagic flux.

  6. An autophagy-related gene, Atg4b, is identified as a de novo target gene of C/EBP BETA (show CEBPB ELISA Kits) and is shown to play an important role in 3T3-L1 adipocyte differentiation.

  7. the RNF5-mediated control of membranalATG4B reveals a novel layer in the regulation of LC3 (show MAP1LC3A ELISA Kits) processing and autophagy.

  8. The Atg4b participates in polarized secretion of lysosomal contents into the extracellular space by directing lysosomes to fuse with the plasma membrane.

  9. Genetic inactivation of mouse Atg4b resulted in amorphous globular bodies in the neuropil of the deep cerebellar nuclei and adjacent vestibular nuclei and a mild but measurable impairment of motor performance on the Rotarod.

  10. The Apg4B/autophagin-1 protease thus serves as a processing/deconjugating enzyme for these four highly divergent mammalian Apg8 homologues, GATE-16 (show GABARAPL2 ELISA Kits), MAP1 (show MOAP1 ELISA Kits)-LC3 (show MAP1LC3A ELISA Kits), GABARAP (show GABARAP ELISA Kits), and Apg8L (show GABARAPL1 ELISA Kits).

ATG4B Antigen Profile

Antigen Summary

Autophagy is the process by which endogenous proteins and damaged organelles are destroyed intracellularly. Autophagy is postulated to be essential for cell homeostasis and cell remodeling during differentiation, metamorphosis, non-apoptotic cell death, and aging. Reduced levels of autophagy have been described in some malignant tumors, and a role for autophagy in controlling the unregulated cell growth linked to cancer has been proposed. This gene encodes a member of the autophagin protein family. The encoded protein is also designated as a member of the C-54 family of cysteine proteases. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Gene names and symbols associated with ATG4B

  • autophagy related 4B cysteine peptidase (ATG4B) antibody
  • autophagy-related 4b (Atg4b) antibody
  • Peptidase family C54 protein (AT3G59950) antibody
  • cysteine protease ATG4B (Tsp_08582) antibody
  • cysteine protease ATG4B (Tsp_11599) antibody
  • ATG4 autophagy related 4 homolog B (S. cerevisiae) (atg4b) antibody
  • autophagy related 4B, cysteine peptidase (atg4b) antibody
  • autophagy related 4B, cysteine peptidase L homeolog (atg4b.L) antibody
  • autophagy related 4B, cysteine peptidase (Atg4b) antibody
  • 2510009N07Rik antibody
  • Apg4b antibody
  • Atg4bl antibody
  • Aut2b2 antibody
  • Autl1 antibody
  • AW048066 antibody

Protein level used designations for ATG4B

ATG4 autophagy related 4 homolog B , cysteine protease ATG4B , autophagy 4b variant 1Cysteine protease ATG4B , autophagy 4b variant 3 , cysteine protease ATG4b , APG4 autophagy 4 homolog B , autophagy-related protein 4 homolog B , AUT2B , autophagin-2B , autophagy-related cysteine endopeptidase 2B , cAut2B , AUT-like 1 cysteine endopeptidase , autophagin-1 , autophagy-related cysteine endopeptidase 1 , hAPG4B , APG4 (ATG4) autophagy-related homolog B , AUT-like 1, cysteine endopeptidase , autophagin 1 , autophagy-related 4B , cysteine protease involved in autophagy APG4-B , autophagy related 4 homolog B , autophagy related 4-like protein B , bAut2B

748674 Pan troglodytes
100067797 Equus caballus
100240691 Zea mays
825165 Arabidopsis thaliana
10907016 Trichinella spiralis
10912977 Trichinella spiralis
100194746 Salmo salar
448859 Danio rerio
404750 Gallus gallus
494717 Xenopus laevis
23192 Homo sapiens
66615 Mus musculus
316640 Rattus norvegicus
609599 Canis lupus familiaris
100462747 Sus scrofa
408002 Bos taurus
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