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ACLY Proteins

(ATP Citrate Lyase (ACLY))

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008].

recommended

ACLY Protein (AA 4-265) (His tag) (ABIN7121924)

ACLY Origin: Human Host: Escherichia coli (E. coli) Recombinant Greater than 95 % as determined by SDS-PAGE ELISA, WB

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recommended

ACLY Protein (AA 1-1101) (Strep Tag) (ABIN3088222)

Crystallography grade ACLY Origin: Human Host: Tobacco (Nicotiana tabacum) Recombinant >80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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recommended

ACLY Protein (AA 1-1091) (Strep Tag) (ABIN3136775)

Crystallography grade ACLY Origin: Mouse Host: Tobacco (Nicotiana tabacum) Recombinant ≥ 80 % as determined by SDS PAGE, Size Exclusion Chromatography and Western Blot. ELISA, WB, SDS

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ACLY Proteins by Grade

Find ACLY Proteins with a specific Grade. The Grade listed below are among those available. Click on a link to go to the corresponding products.

ACLY Proteins by Origin

Find ACLY Proteins for a variety of species such as anti-Human ACLY, anti-Mouse ACLY. The species listed below are among those available. Click on a link to go to the corresponding products.

ACLY Proteins by Source

Here you will find ACLY Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

ACLY Proteins by Protein Type

Here you can find ACLY Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

ACLY Proteins by Application

Find ACLY Proteins validated for a specific application such as ELISA, WB, SDS, AbP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular ACLY Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

ACLY Protein (AA 4-265) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7121924

Quantity 50 μg

Datasheet Datasheet

ACLY Protein (AA 1-1101) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3088222

Quantity 1 mg

Datasheet Datasheet

ACLY Protein (AA 1-1091) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3136775

Quantity 1 mg

Datasheet Datasheet

ACLY Protein (His tag)

Reactivity Human

Source Baculovirus infected Insect Cells

Validations

Cat. No. ABIN7194322

Quantity 50 μg

Datasheet Datasheet

ACLY Protein (Transcript Variant 1) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2715038

Quantity 20 μg

Datasheet Datasheet

Latest Publications for our ACLY Proteins

Chen, Qian, He, Zhao, Toral-Barza, Shi, Zhang, Wu, Yu: "mTOR complex-2 stimulates acetyl-CoA and de novo lipogenesis through ATP citrate lyase in HER2/PIK3CA-hyperactive breast cancer." in: Oncotarget, Vol. 7, Issue 18, pp. 25224-40, (2018) (PubMed).

Aliases for ACLY Proteins

ATP citrate lyase (ACLY) Proteins
ATP citrate lyase S homeolog (acly.S) Proteins
ATP-citrate synthase (LOC587157) Proteins
ATP citrate lyase (acly) Proteins
ATP citrate lyase (ATPCL) Proteins
ATP-citrate synthase (LOC5564509) Proteins
citrate synthase, mitochondrial (CpipJ_CPIJ010291) Proteins
ATP-citrate synthase (Bm1_26245) Proteins
atp-citrate synthase (ACL) Proteins
ATP citrate lyase (Acly) Proteins
ATP citrate lyase a (aclya) Proteins
A730098H14Rik Proteins
ACL Proteins
ACLY Proteins
acly Proteins
anon-WO0140519.179 Proteins
ATPCL Proteins
AW538652 Proteins
BcDNA:LD21334 Proteins
cb722 Proteins
CG8322 Proteins
CLATP Proteins
Clatp Proteins
dATPCL Proteins
DDBDRAFT_0205389 Proteins
DDBDRAFT_0235360 Proteins
DDB_0205389 Proteins
DDB_0235360 Proteins
DmATPCL Proteins
Dmel\\CG8322 Proteins
l(2)01466 Proteins
l(2)k09217 Proteins
n(2)k09217 Proteins
zgc:92008 Proteins

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ACLY Proteins by Grade

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Popular ACLY Proteins

Latest Publications for our ACLY Proteins

Aliases for ACLY Proteins

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