You are viewing an incomplete version of our website. Please click to reload the website as full version.

ATP Citrate Lyase (ACLY) ELISA Kits

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. Additionally we are shipping ACLY Antibodies (98) and ACLY Proteins (4) and many more products for this protein.

list all ELISA KIts Gene Name GeneID UniProt
ACLY 47 P53396
ACLY 104112 Q91V92
ACLY 24159 P16638
How to order from antibodies-online
  • +1 877 302 8632
  • +1 888 205 9894 (toll-free)
  • Order online
  • orders@antibodies-online.com

Top ACLY ELISA Kits at antibodies-online.com

Showing 5 out of 19 products:

Catalog No. Reactivity Sensitivity Range Images Quantity Supplier Delivery Price Details
Human 11.75 pg/mL 47-3000 pg/mL Typical standard curve 96 Tests Log in to see 15 to 18 Days
$910.56
Details
Human
  96 Tests Log in to see 2 to 3 Days
$480.00
Details
Mouse 0.188 ng/mL 0.312-20 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details
Rat 0.375 ng/mL 0.625-40 ng/mL   96 Tests Log in to see 13 to 16 Days
$475.20
Details
Cow
  96 Tests Log in to see 15 to 18 Days
$1,029.60
Details

More ELISA Kits for ACLY Interaction Partners

Human ATP Citrate Lyase (ACLY) interaction partners

  1. CUL3 (show CUL3 ELISA Kits) interacts with ACLY through its adaptor protein, KLHL25 (Kelch-like family member 25), to ubiquitinate and degrade ACLY in cells

  2. we found that depletion of ATP citrate lyase suppressed tumor growth, which suggests that ATP citrate lyase-related inhibitors might be potential therapeutic approaches for breast cancer.

  3. Results show that ACLY is a key phosphoprotein effector of IL-2 (show IL2 ELISA Kits)-mediated T-cell responses. ACLY becomes phosphorylated on serine 455 in T lymphocytes upon IL-2 (show IL2 ELISA Kits)-driven activation of AKT (show AKT1 ELISA Kits), and depletion or inactivation of ACLY compromises IL-2 (show IL2 ELISA Kits)-promoted T-cell growth.

  4. ACLY was also required for LMW-E-mediated transformation, migration, and invasion of breast cancer cells in vitro along with tumor growth in vivo In clinical specimens of breast cancer, the absence of LMW-E and low expression of adipophilin (PLIN2 (show PLIN2 ELISA Kits)), a marker of lipid droplet formation, associated with favorable prognosis

  5. ACC1 (show ACACA ELISA Kits) and ACLY regulate the levels of ETV4 (show ETV4 ELISA Kits) under hypoxia via increased alpha-ketoglutarate. These results reveal that the ACC1 (show ACACA ELISA Kits)/ACLY-alpha-ketoglutarate-ETV4 (show ETV4 ELISA Kits) axis is a novel means by which metabolic states regulate transcriptional output

  6. ACL activity is associated with increased ATP. Activation of this IGF1 (show IGF1 ELISA Kits)/ACL/cardiolipin pathway combines anabolic signaling with induction of mechanisms needed to provide required ATP.

  7. These results suggest that the combined expression of GLUT1 (show SLC2A1 ELISA Kits) and ACLY could be a more valuable prognostic factor than their individual expression in node-negative patients with NSCLC.

  8. Polymorphisms of ATP citrate lyase gene is associated with recurrence in colorectal cancer.

  9. SNP rs9912300 in ACLY gene was significantly associated with response to therapy in hepatocellular carcinoma

  10. The activation of AMPK (show PRKAA1 ELISA Kits) under ACLY knockdown conditions may lead to p53 (show TP53 ELISA Kits) activation, ultimately leading to cellular senescence.

Mouse (Murine) ATP Citrate Lyase (ACLY) interaction partners

  1. ATP-citrate lyase inhibitor bempedoic acid effectively prevents plasma and tissue lipid elevations and attenuates the onset of inflammation, leading to the prevention of atherosclerotic lesion development in a Ldlr (show LDLR ELISA Kits) knockout mouse model of metabolic dysregulation.

  2. IL-4 (show IL4 ELISA Kits) signaling co-opts the Akt (show AKT1 ELISA Kits)-mTORC1 pathway to regulate Acly, a key enzyme in acetyl-CoA (show LPCAT1 ELISA Kits) synthesis, leading to increased histone acetylation and macrophage gene induction.

  3. These data demonstrate that ACLY mediates glucose-dependent de novo lipogenesis in response to LPS (show TLR4 ELISA Kits) signaling and identify a role for ACLY in several phenotypic changes that define plasma cell differentiation

  4. Results suggest a role for DNA methyltransferase 1 (DNMT1 (show DNMT1 ELISA Kits)) in modulating the timing of differentiation and describe a novel ATP-citrate lyase (ACL)-miR (show MLXIP ELISA Kits)-148a-dependent mechanism for regulating DNMT1 (show DNMT1 ELISA Kits) during adipogenesis.

  5. Differences between human and rodent pancreatic islets: low pyruvate carboxylase (show PC ELISA Kits), atp citrate lyase, and pyruvate carboxylation and high glucose-stimulated acetoacetate in human pancreatic islets.

  6. Results demonstrate that hepatic ATP-citrate lyase suppression exerts profound effects on triglyceride mobilization as well as fatty acid compositions in the liver, suggesting an important role for ACL (show APOC4 ELISA Kits) in lipid metabolism.

  7. Data suggest that ATP-citrate lyase (ACLY) expression and activity can be suppressed by exogenous lipids and demonstrate a critical role for ACLY in pancreatic beta cell survival.

  8. crucial role of hepatic ATP-citrate lyase in lipid and glucose metabolism

  9. findings suggest that ATP-citrate lyase activity is required to link growth factor-induced increases in nutrient metabolism to the regulation of histone acetylation and gene expression

Pig (Porcine) ATP Citrate Lyase (ACLY) interaction partners

  1. The results of this study indicate that a C/T mutation affects ACL mRNA expression, probably via the activator protein 2 (show TFAP2A ELISA Kits).

Cow (Bovine) ATP Citrate Lyase (ACLY) interaction partners

  1. we identified three non-synonymous mutations in ACLY exons in five beef cattle populations. Single nucleotide polymorphism (SNP) g.17127C>T is significantly associated with chest girth and body height, and with body slanting length. SNP g.40427T>C is significantly associated with an increase in chest girth. ACLY gene are associated with growth traits in beef cattle in northwest China

ACLY Antigen Profile

Antigen Summary

ATP citrate lyase is the primary enzyme responsible for the synthesis of cytosolic acetyl-CoA in many tissues. The enzyme is a tetramer (relative molecular weight approximately 440,000) of apparently identical subunits. It catalyzes the formation of acetyl-CoA and oxaloacetate from citrate and CoA with a concomitant hydrolysis of ATP to ADP and phosphate. The product, acetyl-CoA, serves several important biosynthetic pathways, including lipogenesis and cholesterogenesis. In nervous tissue, ATP citrate-lyase may be involved in the biosynthesis of acetylcholine. Two transcript variants encoding distinct isoforms have been identified for this gene.

Gene names and symbols associated with ATP Citrate Lyase (ACLY) ELISA Kits

  • ATP citrate lyase (ACLY) antibody
  • ATP citrate lyase (acly) antibody
  • ATP citrate lyase (ATPCL) antibody
  • ATP-citrate synthase (AaeL_AAEL004297) antibody
  • citrate synthase, mitochondrial (CpipJ_CPIJ010291) antibody
  • ATP-citrate synthase (Bm1_26245) antibody
  • atp-citrate synthase (ACL) antibody
  • ATP citrate lyase (Acly) antibody
  • ATP citrate lyase a (aclya) antibody
  • A730098H14Rik antibody
  • ACL antibody
  • acly antibody
  • anon-WO0140519.179 antibody
  • ATPCL antibody
  • AW538652 antibody
  • BcDNA:LD21334 antibody
  • cb722 antibody
  • CG8322 antibody
  • Clatp antibody
  • dATPCL antibody
  • DDBDRAFT_0205389 antibody
  • DDBDRAFT_0235360 antibody
  • DDB_0205389 antibody
  • DDB_0235360 antibody
  • DmATPCL antibody
  • Dmel\\CG8322 antibody
  • l(2)01466 antibody
  • l(2)k09217 antibody
  • n(2)k09217 antibody
  • zgc:92008 antibody

Protein level used designations for ATP Citrate Lyase (ACLY) ELISA Kits

ATP citrate lyase , ATP citrate synthase , ATP-citrate synthase-like , ATP-citrate lyase , ATPCL-PD , ATPCL-PE , ATPCL-PF , CG8322-PD , CG8322-PE , CG8322-PF , ATP-citrate synthase , citrate synthase, mitochondrial , atp-citrate synthase , ATP-citrate (pro-S-)-lyase , citrate cleavage enzyme

GENE ID SPECIES
100053195 Equus caballus
454672 Pan troglodytes
495086 Xenopus laevis
587157 Strongylocentrotus purpuratus
708501 Macaca mulatta
8621508 Dictyostelium discoideum AX4
100405725 Callithrix jacchus
100422779 Felis catus
100439535 Pongo abelii
100467494 Ailuropoda melanoleuca
36760 Drosophila melanogaster
5564509 Aedes aegypti
6042632 Culex quinquefasciatus
6100149 Brugia malayi
7201075 Phaeodactylum tricornutum CCAP 1055/1
47 Homo sapiens
104112 Mus musculus
24159 Rattus norvegicus
100125957 Sus scrofa
511135 Bos taurus
395373 Gallus gallus
607852 Canis lupus familiaris
654404 Ovis aries
436922 Danio rerio
Selected quality suppliers for ACLY (ACLY) ELISA Kits
Did you look for something else?