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ATPAF2 encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. Additionally we are shipping ATPAF2 Antibodies (27) and many more products for this protein.
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Two possible dementia susceptibility genes including ATPAF2 and TOM1L2 (show TOM1L2 Proteins) near SREBF1 (show SREBF1 Proteins) locus were identified.
Data show that wild type human Atp12p rescues the respiratory defect of a yeast ATP12 deletion mutant (Deltaatp12).
This gene encodes an assembly factor for the F(1) component of the mitochondrial ATP synthase. This protein binds specifically to the F1 alpha subunit and is thought to prevent this subunit from forming nonproductive homooligomers during enzyme assembly. This gene is located within the Smith-Magenis syndrome region on chromosome 17. An alternatively spliced transcript variant has been described, but its biological validity has not been determined.
ATP synthase mitochondrial F1 complex assembly factor 2
, ATP12 homolog