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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) Antibodies

The membrane-associated protein encoded by ABCA1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA1 Kits (35) and ABCA1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCA1 19 O95477
ABCA1 11303 P41233
ABCA1 313210  
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Top anti-ABCA1 Antibodies at antibodies-online.com

Showing 10 out of 179 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Mouse Rat Un-conjugated IHC (p), WB Western Blot: ABCA1 Antibody (3A1.891.3) [ABIN438227] - Detection of ABCA1 using NB 400-164 at various dilutions in ABCA1 transfected HeLa lysates. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Chicken Rabbit Un-conjugated ChIP, ELISA, FACS, GS, ICC, IF, IHC, IHC (fro), IHC (p), IP, SimWes, WB Western Blot analysis of ABCA1, using ABIN152883. Samples: 40 ug of total cell post-nuclear lysate of raw macrophages treated with 9-cisretinoic acid and 22R-hydroxycholesterol. Detection of ABCA1 in mouse peritoneal macrophages using ABIN152883 (Lot L). ECL exposure, 1 min. Lane 4: T09 uninduced lysate Lane 5: T09 induced lysate 0.1 mL Log in to see 5 to 7 Days
$473.81
Details
Human Mouse Un-conjugated CyTOF, FACS, IHC, IHC (p), WB Flow Cytometry: ABCA1 Antibody (HJ1) [ABIN4277133] - Flow cytometric staining of 1 x 10^6 CHO (A) and HEK-293 (B) cells using ABCA1 antibody (dark blue). Isotype control shown in orange. An antibody concentration of 1 ug/1x10^6 cells was used. Western Blot: ABCA1 Antibody (HJ1) [ABIN4277133] - Detection of ABCA1 in wildtype liver tissue (in RIPA) Lane 1: KO mouse liver tissue. Lane 2: WT mouse liver tissue. 0.1 mL Log in to see 5 to 7 Days
$408.19
Details
Human Rabbit Un-conjugated FACS, IF (p), IHC (p) Formalin-fixed and paraffin embedded rat ovary tissue labeled with Anti-ABCA1/ABC1 Polyclonal Antibody, Unconjugated (ABIN732188) at 1:200 followed by conjugation to the secondary antibody, (SP-0023), and DAB staining Formalin-fixed and paraffin embedded rat uterus tissue labeled with Anti-ABCA1/ABC1 Polyclonal Antibody, Unconjugated (ABIN732188) at 1:200 followed by conjugation to the secondary antibody, (SP-0023), and DAB staining 100 μL Log in to see 3 to 7 Days
$307.45
Details
Chicken Mouse Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated WB Anti- ABCA1 Picoband antibody, Western blotting All lanes: Anti ABCA1  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Lane 3: SMMC Whole Cell Lysate at 40ug Predicted bind size: 254KD Observed bind size: 254KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated WB Anti-ABCA1 antibody, Western blotting Lane 1: Rat Brain Tissue Lysate Lane 2:  Cell Lysate Lane 3: HELA Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC (p), ELISA, WB Human Skeletal Muscle (formalin-fixed, paraffin-embedded) stained with ABCA1 antibody ABIN337112 at 10 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$451.00
Details
Chicken Rabbit Biotin ELISA, ICC, IF, IHC (fro), IHC (p), WB   0.1 mL Log in to see 5 to 7 Days
$500.06
Details

ABCA1 Antibodies by Reactivity, Application, Clonality and Conjugate

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Top referenced anti-ABCA1 Antibodies

  1. Chicken Polyclonal ABCA1 Primary Antibody for ChIP, ELISA - ABIN152883 : Krimbou, Denis, Haidar, Carrier, Marcil, Genest: Molecular interactions between apoE and ABCA1: impact on apoE lipidation. in Journal of lipid research 2004 (PubMed)
    Show all 243 references for ABIN152883

  2. Chicken Polyclonal ABCA1 Primary Antibody for ELISA, ICC - ABIN268847 : Burgess, Kiss, Zheng, Zachariah, Marcel: Trypsin-sensitive and lipid-containing sites of the macrophage extracellular matrix bind apolipoprotein A-I and participate in ABCA1-dependent cholesterol efflux. in The Journal of biological chemistry 2002 (PubMed)
    Show all 13 references for ABIN268847

  3. Mouse (Murine) Monoclonal ABCA1 Primary Antibody for IHC (p), WB - ABIN268899 : Zhou, Choi, Li, Xu, Herz: LRP1 controls cPLA2 phosphorylation, ABCA1 expression and cellular cholesterol export. in PLoS ONE 2009 (PubMed)
    Show all 6 references for ABIN268899

  4. Human Monoclonal ABCA1 Primary Antibody for CyTOF, FACS - ABIN4277133 : Wang, Zhang, Chou, Liang, Gu, Ma: Cyclosporine stimulates the renal epithelial sodium channel by elevating cholesterol. in American journal of physiology. Renal physiology 2009 (PubMed)
    Show all 5 references for ABIN4277133

  5. Human Polyclonal ABCA1 Primary Antibody for FACS, IF (p) - ABIN732188 : Jia, Song, Yang, Ma, Li, Lu, Cao, Zhang, Zhu, Wang, Leng, Cao, Du, Xu: Effects of Tanshinone IIA on the modulation of miR‑33a and the SREBP‑2/Pcsk9 signaling pathway in hyperlipidemic rats. in Molecular medicine reports 2016 (PubMed)

  6. Human Polyclonal ABCA1 Primary Antibody for WB - ABIN2781512 : Fu, Mukhamedova, Ip, DSouza, Henley, DiTommaso, Kesani, Ditiatkovski, Jones, Lane, Jennings, Smyth, Kile, Sviridov: ABCA12 regulates ABCA1-dependent cholesterol efflux from macrophages and the development of atherosclerosis. in Cell metabolism 2013 (PubMed)

More Antibodies against ABCA1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. our results highlight the importance of the LXR (show NR1H3 Antibodies)/ABCA1 system in brain pericytes and suggest a new role for these cells in brain cholesterol homeostasis.

  2. The expression and distribution of the bovine ABCA1 transporter using quantitative PCR and the sequencing of the entire ABCA1 coding region, including the proximal promoter region, are reported.

  3. Aortic endothelial cells transcytose high-density lipoproteins by mechanisms that involve either SR-BI (show SCARB1 Antibodies) or ABCG1 (show ABCG1 Antibodies) but not ABCA1.

Rabbit ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. CSL112 elevation of ABCA1-dependent efflux may target atherosclerotic plaque for cholesterol removal.

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. ApoA-I (show APOA1 Antibodies) induces S1P (show MBTPS1 Antibodies) release from endothelial cells through ABCA1 and SR-BI (show SCARB1 Antibodies) in a positive feedback manner.

  2. Results suggest that enhanced expression of miR (show MLXIP Antibodies)-33a might induce cholesterol accumulation and aggravate inflammation in vessel walls by suppressing the expression of ABCA1 in macrophages.

  3. AIBP (show APOA1BP Antibodies) promotes apoA-1 (show APOA1 Antibodies) binding to ABCA1 on the cell membrane of macrophages and prevents ABCA1 protein from CSN2 (show CSN2 Antibodies)-mediated degradation so as to prevent foam cell formation

  4. ABCA1 gene expression positively correlated with obesity indicators.

  5. The results of this study indicated that ABCA1 rs2422493 polymorphism was statistically significant associated with increasing Alzheimer's disease risk.

  6. These findings suggest that some common variants on the chromosome 9p21 and ABCA1 and their interactions may significantly modify the risk of Coronary Heart Disease and is independent of effects on serum lipid levels.

  7. In people with mild cognitive impairement and Alzheimer disease, the capacity of CSF (show CSF2 Antibodies) to facilitate ABCA1-mediated cholesterol efflux is impaired.

  8. miR (show MLXIP Antibodies)-183 degrades ABCA1 mRNA in colon cancer cells.

  9. Absence of ABCA1 and low HDL (show HSD11B1 Antibodies) level induce reduction of platelet reactivity by decreasing positive feedback loops, particularly TXA2 (show TBXA2R Antibodies) production through a hematopoietic ABCA1-independent mechanism.

  10. rs708272 polymorphism showed protective effect (B1 vs. B2: OR = 0.80, P = 0.003 and B2B2 vs. B1B1: OR = 0.68, P = 0.012) while the ABCA1 variant rs2066715 was not associated

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. The ABCA1 may serve as an important feedback mechanism to modulate the magnitude of subsequent phagocytotic process of SCs (show TWIST1 Antibodies) in response to testicular injury.

  2. Absence of ABCA1 and low HDL (show HSD11B1 Antibodies) level induce reduction of platelet reactivity by decreasing positive feedback loops, particularly TXA2 (show TBXA2R Antibodies) production through a hematopoietic ABCA1-independent mechanism.

  3. Both depletion of PARP-1 (show PARP1 Antibodies) and inhibition of PARP-1 (show PARP1 Antibodies) activity augmented LXR (show NR1H3 Antibodies) ligand-induced ABCA1 expression in the RAW 264.7 macrophage line and primary bone marrow-derived macrophages but did not affect LXR (show NR1H3 Antibodies)-dependent expression of other target genes, ABCG1 (show ABCG1 Antibodies) and SREBP-1c (show SREBF1 Antibodies).

  4. Visfatin (show NAMPT Antibodies) upregulated CD36 (show CD36 Antibodies) and SRA (show MSR1 Antibodies) expression and downregulated ABCA1 and ABCG1 (show ABCG1 Antibodies) expression, subsequently increased ox-LDL uptake and decreased cholesterol efflux, and finally promoted foam cell formation via the PI3K- and ERK (show EPHB2 Antibodies)-dependent pathways.

  5. These studies point to an important role for hematopoietic ABCA1 in modulating a feed-forward mechanism in obesity such that inflamed tissue macrophages stimulate the production of more monocytes, leading to an exacerbation of inflammation and associated disease processes.

  6. These findings may be clinically relevant because HDL's APOE (show APOE Antibodies) content associates with CVD risk and ABCA1 deficiency promotes unregulated cholesterol accumulation in human macrophages.

  7. Short-term modulation of miR (show MLXIP Antibodies)-27b expression in wild-type mice regulates hepatic LDLR (show LDLR Antibodies) and ABCA1 expression but does not influence plasma and hepatic lipid levels.

  8. LXR (show NR1H3 Antibodies) activation reduces the growth of xenograft tumour of human oral squamous cell carcinoma cells in mice accompanied by the upregulation of ABCA1 expression and the decline of cholesterol levels in the tumour.

  9. PGG enhances expression of SR-BI (show SCARB1 Antibodies) and ABCA1 in J774 and THP-1 (show GLI2 Antibodies) macrophages

  10. ABCA1(-/-) macrophages deposited much less extracellular cholesterol than wild-type macrophages. These findings demonstrate a novel function of ABCA1 in contributing to macrophage export of cholesterol into the extracellular matrix.

Pig (Porcine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 1 (ABCA1) interaction partners

  1. ABCA1 promoter variants affect transcription activity and plasma HDL (show HSD11B1 Antibodies) level in pigs

  2. ABCA1 was up-regulated in monocytes of hypercholesterolemic pigs via oxidized-LDL and prior to development coronary atherosclerosis.

  3. Both region-specific and ubiquitous (ABCA1) phenotype changes were identified as early prelesional responses of the endothelium to hypercholesterolemia

ABCA1 Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. With cholesterol as its substrate, this protein functions as a cholesteral efflux pump in the cellular lipid removal pathway. Mutations in this gene have been associated with Tangier's disease and familial high-density lipoprotein deficiency.

Gene names and symbols associated with ABCA1

  • ATP-binding cassette, sub-family A (ABC1), member 1 (ABCA1) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 1 (abca1) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 1 (Abca1) antibody
  • ATP-binding cassette, subfamily A (ABC1), member 1 (Abca1) antibody
  • ABC-1 antibody
  • Abc1 antibody
  • ABCA1 antibody
  • CERP antibody
  • HDLDT1 antibody
  • TGD antibody

Protein level used designations for ABCA1

ATP-binding cassette, sub-family A member 1 , ATP-binding cassette transporter 1 , Cholesterol efflux regulatory protein , ATP-binding cassette sub-family A member 1 , ATP-binding cassette transporter , ATP-binding cassette, sub-family A (ABC1), member 1 , ATP-binding cassette, sub-family A member 1-like , ATP-binding cassette sub-family A member 1-like , ATP-binding cassette transporter A1 , cholesterol efflux regulatory protein , membrane-bound , ATP-binding cassette 1

GENE ID SPECIES
464630 Pan troglodytes
535379 Bos taurus
100013781 Monodelphis domestica
100356765 Oryctolagus cuniculus
100441342 Pongo abelii
100483394 Ailuropoda melanoleuca
100491942 Xenopus (Silurana) tropicalis
716107 Macaca mulatta
100557081 Anolis carolinensis
373945 Gallus gallus
19 Homo sapiens
11303 Mus musculus
481651 Canis lupus familiaris
100152112 Sus scrofa
313210 Rattus norvegicus
Selected quality suppliers for anti-ABCA1 (ABCA1) Antibodies
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