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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) Antibodies

The membrane-associated protein encoded by ABCA12 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA12 Kits (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCA12 26154 Q86UK0
ABCA12 74591  
ABCA12 301482  
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Top anti-ABCA12 Antibodies at antibodies-online.com

Showing 10 out of 33 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Rabbit Un-conjugated WB 50 μg Log in to see 8 to 10 Days
$551.83
Details
Human Rabbit Un-conjugated IF (p), IHC (p) Formalin-fixed and paraffin embedded mouse embryo labeled with Anti-ABCA12 Polyclonal Antibody, Unconjugated (ABIN1386605) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Human Rabbit Un-conjugated WB Human Stomach; WB Suggested Anti-ABCA12 Antibody Titration: 0.2-1 ug/ml. Positive Control: Human Stomach; ABCA12 antibody - middle region in Human Stomach cells using Western Blot 50 μg Log in to see 6 to 8 Days
$401.50
Details
Human Goat Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$419.83
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Goat Un-conjugated ELISA, WB   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Human Rabbit Un-conjugated WB ABCA12 antibody used at 1 ug/ml to detect target protein. 50 μg Log in to see 3 to 4 Days
$473.93
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ABCA12 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABCA12 Antibodies

  1. Human Polyclonal ABCA12 Primary Antibody for WB - ABIN2781522 : Hlaváč, Brynychová, Václavíková, Ehrlichová, Vrána, Pecha, Koževnikovová, Trnková, Gatěk, Kopperová, Gut, Souček: The expression profile of ATP-binding cassette transporter genes in breast carcinoma. in Pharmacogenomics 2013 (PubMed)

More Antibodies against ABCA12 Interaction Partners

Zebrafish ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. The morphological findings are akin to epidermal changes in harlequin ichthyosis (show CST6 Antibodies) and CEDNIK (show SNAP29 Antibodies) syndrome, autosomal recessive keratinization disorders due to mutations in the ABCA12 and SNAP29 (show SNAP29 Antibodies) genes, respectively.

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. Autosomal recessive inheritance of mutations in the ATP-binding cassette, subfamily A (show CYP Antibodies), member 12 (ABCA12, OMIM*607800, chromosome 2q35) gene was found to be responsible for the disease.

  2. Identification of the key promoter element of ABCA12 in this study may provide relevant information for genetic diagnosis of recessive congenital ichthyosis (show LBR Antibodies).

  3. Ssnger sequencing of the parents of neonates deceased patients with Harlequin ichthyosis (show CST6 Antibodies) identified novel mutations in ABCA12 gene.

  4. ABCA12 mutations result in defective lipid transport via lamellar granules in the keratinocytes, leading to ichthyosis (show LBR Antibodies) phenotypes from malformation of the stratum corneum lipid barrier.

  5. Report a consanguineous family of Arab Muslim origin with several members displaying a severe form of congenital ichthyosiform erythroderma. Identified a region of homozygosity shared by all patients on 2q34, in a region harbouring the ABCA12 gene.

  6. We show that homozygosity for a novel c.4676G>T transition in the ABCA12 gene, resulting in a p.G1559V substitution, causes non-bullous congenital ichthyosiform erythroderms in 5 members of an extended family.

  7. The authors report on a 2282del4 mutation that may be associated with ichthyosis (show LBR Antibodies) vulgaris in a Pakistani population.

  8. The researchers report on another fatal case of Harlequin ichthyosis (show CST6 Antibodies) that may be associated with mutations of the ABCA12 gene

  9. AKT (show AKT1 Antibodies) signaling helps ABCA12 deficient keratinocytes survive during the keratinization process.

  10. Mutation analysis revealed that 52% of the survivors of harlequin ichthyosis (show CST6 Antibodies) had compound heterozygous mutations of ABCA12, whereas all deaths were associated with homozygous mutations of ABCA12.

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 12 (ABCA12) interaction partners

  1. Data indicate that ABC transporter A family member 12 knockout (Abca12(-/-)) epidermis had 5-fold more beta-glucocerebrosidase (GCase (show GBA Antibodies)) protein, and a 5-fold increase in GCase (show GBA Antibodies) activity.

  2. ABCA12 mutations result in defective lipid transport via lamellar granules in the keratinocytes, leading to ichthyosis (show LBR Antibodies) phenotypes from malformation of the stratum corneum lipid barrier.

  3. ABCA12 regulates the cellular cholesterol metabolism via an LXRbeta (show NR1H2 Antibodies)-dependent posttranscriptional mechanism.

  4. Results indicate that disrupted keratinocyte differentiation during the fetal development is involved in the pathomechanism of HI and, during maturation, Abca12(-/-) epidermal keratinocytes regain normal differentiation processes.

  5. ABCA12 plays pivotal roles in lung and skin barrier functions in Harlequin ichthyosis (show CST6 Antibodies) disease midel.

  6. Abca12 is a regulator of lipid transport and homeostasis.

  7. ABCA12 activity is required for the generation of long-chain ceramide esters that are essential for the development of normal skin structure and function

ABCA12 Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, and White). This encoded protein is a member of the ABC1 subfamily, which is the only major ABC subfamily found exclusively in multicellular eukaryotes. Alternative splicing of this gene results in multiple transcript variants.

Gene names and symbols associated with ABCA12

  • ATP-binding cassette, sub-family A (ABC1), member 12 (ABCA12) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 12 (abca12) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 12 (Abca12) antibody
  • ATP-binding cassette, subfamily A (ABC1), member 12 (Abca12) antibody
  • 4832428G11Rik antibody
  • 4833417A11Rik antibody
  • ARCI4A antibody
  • ARCI4B antibody
  • cb352 antibody
  • ICR2B antibody
  • LI2 antibody
  • sb:cb352 antibody

Protein level used designations for ABCA12

ATP-binding cassette, sub-family A (ABC1), member 12 , ATP-binding cassette, sub-family A, member 12 , ATP-binding cassette sub-family A member 12 , ATP-binding cassette sub-family A member 12-like , ATP-binding cassette transporter 12

GENE ID SPECIES
424011 Gallus gallus
459924 Pan troglodytes
523479 Bos taurus
558335 Danio rerio
694427 Macaca mulatta
100341171 Oryctolagus cuniculus
100464882 Ailuropoda melanoleuca
26154 Homo sapiens
478900 Canis lupus familiaris
100512445 Sus scrofa
74591 Mus musculus
301482 Rattus norvegicus
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