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anti-ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) Antibodies

The membrane-associated protein encoded by ABCA2 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCA2 Kits (8) and and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCA2 20 Q9BZC7
ABCA2 11305  
ABCA2 79248 Q9ESR9
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Top anti-ABCA2 Antibodies at antibodies-online.com

Showing 10 out of 67 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated WB 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Goat Un-conjugated IHC (p), ELISA Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μg Log in to see 8 to 10 Days
$451.00
Details
Human Goat Un-conjugated ELISA, WB   100 μg Log in to see 4 to 5 Days
$221.76
Details
Mouse Rat PE FACS   100 Tests Log in to see 8 to 10 Days
$625.17
Details
Mouse Rat PE FACS 100 Tests Log in to see 11 to 16 Days
$357.14
Details
Mouse Rat Un-conjugated FACS, WB   250 μg Log in to see 8 to 10 Days
$449.17
Details
Human Goat Un-conjugated ELISA   0.1 mg Log in to see 2 to 3 Days
$433.13
Details
Mouse Rat Un-conjugated FACS, WB 0.25 mg Log in to see 11 to 16 Days
$421.43
Details
Human Rabbit Alexa Fluor 594 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details
Human Rabbit Alexa Fluor 350 IF (p)   100 μL Log in to see 14 to 21 Days
$357.50
Details

ABCA2 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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More Antibodies against ABCA2 Interaction Partners

Human ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. Our findings indicate a considerable and direct relationship between mRNA expression levels of ABCA2, ABCA3 (show ABCA3 Antibodies), MDR1 (show TBC1D9 Antibodies), and MRP1 (show MDM4 Antibodies) genes and positive minimal residual disease (MRD) measured after one year of treatment.

  2. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (show NCSTN Antibodies) maturation and intracellular localization.

  3. SLC2A1/GLUT1 (show SLC2A1 Antibodies), SLC1A3/EAAT1 (show SLC1A3 Antibodies), and SLC1A2/EAAT2 (show SLC1A2 Antibodies) were the main SLC (show CCL21 Antibodies) proteins whereas ABCG2/BCRP (show ABCG2 Antibodies), ABCB1/MDR1 (show ABCB4 Antibodies), ABCA2 and ABCA8 (show ABCA8 Antibodies) were the main ABC (show ABCB6 Antibodies) quantified in isolated brain microvessels

  4. A possible biochemical mechanism links ABCA2 expression, amyloid precursor protein (show APP Antibodies) processing, and Alzheimer's disease.

  5. we demonstrate that ABCA2-deficiency inhibits prostate tumor metastasis in vivo and decreases chemotactic potential of cells

  6. roles for this largest known ABC (show ABCB6 Antibodies) protein in neural transmembrane lipid export

  7. Reciprocal regulation of expression of the ABCA2 promoter by the early growth response-1 (show EGR1 Antibodies) and Sp-family transcription factors.

  8. It is likely that expression of ABCA2 by two independent promoters constitutes locus of regulation controlling expression of the protein to meet requirements in different tissues.

  9. Increased expression of ABCA2 may be causally linked with altered expression of genes associated with the pathogenesis of Alzheimer disease.

  10. Among the 45 ABCA2 single nucleotide polymorphisms(SNPs) we tested, one synonymous SNP (rs908832) was found significantly associated with AD in both samples.

Mouse (Murine) ATP-Binding Cassette, Sub-Family A (ABC1), Member 2 (ABCA2) interaction partners

  1. Study suggests that ABCA2 modulation of sphingolipid metabolism activates a signaling pathway that regulates amyloid precursor protein (show APP Antibodies) transcription

  2. control of ABCA2 expression level may be a key locus of regulation for esterification of plasma membrane-derived cholesterol through modulation of sphingolipid metabolism.

  3. Data from knockout mice suggest that Abca2 functions in penile erection; Abca2 knockout mice are more susceptible to estrogen-induced convulsions than wildtype mice; Abca2 appears to be involved in biotransformation of therapeutic estrogens.

  4. Lack of ABCA2 generates abnormalities in intracellular lipid distribution/trafficking in macrophages, increasing susceptibility to apoptosis in response to oxidized lipids and reduced atherosclerotic lesion development in LDL receptor (show LDLR Antibodies) knockout mice.

  5. The ATP-binding cassette transporter-2 (ABCA2) is a key regulator of cholesterol homeostasis and low-density lipoprotein receptor (show LDLR Antibodies) metabolism in neuronal cells.

  6. Down-regulation of the ATP-binding cassette transporter 2 (Abca2) reduces amyloid-beta production by altering Nicastrin (show NCSTN Antibodies) maturation and intracellular localization.

  7. ABC-me (show ABCB10 Antibodies) is a novel gene that determines the ability to tolerate cardiac ischemia/reperfusion.

  8. ABCA2 has a role in myelin compaction in spinal cord and cerebrum, and in phenotypic tremor

  9. ABCA2 is expressed in non-myelin-forming as well as in myelin-forming Schwann cells. ABCA2 may be involved in transport of a substance associated with cellular maturation rather than initial myelin formation in both types of Schwann cells.

  10. ABCA2 is involved in the intracellular metabolism of sphingolipids in the brain, particularly SM and gangliosides in oligodendrocytes and certain neurons.

ABCA2 Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intracellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the ABC1 subfamily. Members of the ABC1 subfamily comprise the only major ABC subfamily found exclusively in multicellular eukaryotes. This protein is highly expressed in brain tissue and may play a role in macrophage lipid metabolism and neural development. Two transcript variants encoding different isoforms have been found for this gene.

Gene names and symbols associated with ABCA2

  • ATP-binding cassette, sub-family A (ABC1), member 2 (ABCA2) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 2 (abca2) antibody
  • SMG8 nonsense mediated mRNA decay factor (smg8) antibody
  • ATP-binding cassette, sub-family A (ABC1), member 2 (Abca2) antibody
  • ATP-binding cassette, subfamily A (ABC1), member 2 (Abca2) antibody
  • Abc2 antibody
  • AI413825 antibody
  • c17orf71 antibody
  • D2H0S1474E antibody
  • mKIAA1062 antibody
  • si:dkey-266h7.1 antibody

Protein level used designations for ABCA2

ATP-binding cassette, sub-family A (ABC1), member 2 , ATP-binding cassette sub-family A member 2-like , protein smg-8 homolog , protein smg8 , smg-8 homolog, nonsense mediated mRNA decay factor , ATP-binding cassette 2 , ATP-binding cassette sub-family A member 2 , ATP-binding cassette transporter 2 , ATP-binding cassette, sub-family A, member 2

GENE ID SPECIES
100067889 Equus caballus
426955 Gallus gallus
100124617 Danio rerio
100231140 Taeniopygia guttata
100498548 Xenopus (Silurana) tropicalis
100017432 Monodelphis domestica
779744 Xenopus (Silurana) tropicalis
20 Homo sapiens
11305 Mus musculus
480669 Canis lupus familiaris
100299651 Bos taurus
79248 Rattus norvegicus
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