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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antibodies

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (11) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 194 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detecti... 25 μL Log in to see 2 to 3 Days
$135.00
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:... 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 6 to 8 Days
$335.50
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated IHC (p), WB Human Vessel: Formalin-Fixed, Paraffin-Embedded (FFPE) 50 μL Log in to see 8 to 10 Days
$451.00
Details
Dog Rabbit Un-conjugated EIA, IHC (p), WB 50 μg Log in to see 6 to 8 Days
$500.50
Details

ABCB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality
Human , , , ,
,
Rat (Rattus) , , ,

Mouse (Murine) , , ,

Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies

  1. Dog (Canine) Polyclonal ABCB1 Primary Antibody for EIA, WB - ABIN401371 : Baker, Johnstone, Zalcberg, El-Osta: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. in Oncogene 2005 (PubMed)
    Show all 6 references for ABIN401371

  2. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 2 references for ABIN317070

  3. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for ABIN1724927

  4. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. in Human genetics 1987 (PubMed)
    Show all 2 references for ABIN1106124

  5. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

  6. Human Monoclonal ABCB1 Primary Antibody for FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp (show ABCG2 Antibodies) and Mrp1 (show ABCC1 Antibodies) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. polymorphisms in ABCB1 gene may contribute to inter-individual variation in carbamazepine and in CBZ-E transport among patients with epilepsy using CBZ

  2. An upregulation of P-gp (show ABCB4 Antibodies) was observed when artemisone and dihydroartemisinin were co-incubated with mefloquine and amodiaquine.

  3. we found that patients carrying the CT+CC genotype of ABCB1 C3435T were more likely to have a better neurological outcome when compared with the TT genotype

  4. To investigate the relationship between ABCB1 single-nucleotide polymorphisms and the efficacy of salmeterol/fluticasone combination (SFC) inhalation therapy for stable chronic obstructive pulmonary disease (COPD (show ARCN1 Antibodies)

  5. Data suggest that activities of human ABCB1 and mouse Abcb1a/Mdr1a (show ABCB4 Antibodies) are unaltered (that is, efflux of fluorescent dyes is unaltered) in chimeric forms created by exchange of homologous transmembrane/nucleotide-binding domains of ABCB1 and Abcb1a/Mdr1a (show ABCB4 Antibodies).

  6. nuclear MRP1 (show MDM4 Antibodies) is highly associated with better prognosis of human mucoepidermoid carcinoma.

  7. P-gp (show ABCB4 Antibodies) expression in the brain is limited at birth, increases with postnatal maturation, and reaches adult levels at ~3-6 mo of age.

  8. MDR1 (show TBC1D9 Antibodies) was detectable in the PC cell line 22Rv1. However, this study suggests that MDR1 (show TBC1D9 Antibodies) is of less importance for drug resistance in PC cells than in other types of solid cancer.

  9. Ser291-phosphorylated form of the multifunctional protein and stem cell marker, CD44 (show CD44 Antibodies), inhibits FBXO21 (show FBXO21 Antibodies)-directed degradation of P-gp (show ABCB4 Antibodies).

  10. MDR1 (show TBC1D9 Antibodies)-luciferase reporter mice provided a unique in vivo system to visualize MDR1 (show TBC1D9 Antibodies) CNS expression and regulation.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  2. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

  3. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (show NFE2L2 Antibodies).

  4. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

  5. Real-time polymerase chain reaction for ABC (show ABCB6 Antibodies) transporters demonstrated that Abcb1a (show ABCB4 Antibodies), Abcb1b (show ABCB4 Antibodies) and Abcg2 (show ABCG2 Antibodies), regarded as stem cell markers, were characteristically expressed in TtT/GF cells but not in Tpit (show TBX19 Antibodies)/F1 and LbetaT2 cells.

  6. In addition to ABCB1-mediated transport.

  7. In single Bcrp1 (show BANF1 Antibodies)(-/-) mice, brain accumulation of CYT387 was more substantially increased than in Mdr1a (show ABCB4 Antibodies)/1b(-/-) mice, suggesting that CYT387 is a slightly better substrate of Bcrp1 (show BANF1 Antibodies) than of Mdr1a (show ABCB4 Antibodies) at the blood-brain barrier.

  8. In Bcrp1;Mrp2;Mrp3(-/-), but not Bcrp1;Mdr1a/b;Mrp(-/-) mice.

  9. Data suggest that neither Mdr1a (show ABCB4 Antibodies) nor Mdr1b are involved in transepithelial transport of herbicide paraquat; brain-to-plasma partitioning ratios and total brain accumulation of paraquat were same across doses between wildtype Mdr1a (show ABCB4 Antibodies)/Mdr1b knockout mice.

  10. These results indicate that radixin (show RDX Antibodies) plays an important role in regulating P-glycoprotein localization and P-glycoprotein functional activity at the intestinal membrane.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • Cd243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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