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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antibodies

The membrane-associated protein encoded by ABCB1 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Kits (11) and ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Proteins (8) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB1 5243 P08183
ABCB1 170913  
ABCB1 18669 P06795
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Top anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies at antibodies-online.com

Showing 10 out of 246 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Dog Rabbit Un-conjugated EIA, WB 0.1 mg Log in to see 6 to 8 Days
$500.50
Details
Human Rabbit Un-conjugated ELISA, WB Western blot using affinity purified anti-ABCB1 antibody shows detection of ABCB1 in crude membrane extracts from HF insect cells over-expressing human ABCB1. The extract was loaded onto a gel in the amounts indicated followed by electrophoresis and transfer to nitrocellulose. The membrane was probed with the primary antibody diluted to 1:600, followed by Peroxidase Conjugated Affinity Purified Anti-RABBIT IgG at 1:10,000. 25 μL Log in to see 2 to 3 Days
$135.00
Details
Dog Mouse Un-conjugated BP, ICC, IF, IHC, IHC (p), IP, Neut, WB Western Blot: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Analysis of MDR1 in OSW canine lymphoma cell line using anti-MDR1 antibody. Image from verified customer review. Immunohistochemistry-Paraffin: MDR1/ABCB1 Antibody (C219) [ABIN153083] - Staining of formalin fixed paraffin embedded human liver tissue. 0.25 mL Log in to see 5 to 7 Days
$381.94
Details
Human Mouse Un-conjugated IHC (fro), IF, IHC (p), WB   0.1 mg Log in to see 6 to 8 Days
$313.50
Details
Human Mouse Un-conjugated ELISA, WB 0.1 mg Log in to see 3 to 4 Days
$430.10
Details
Human Rabbit Un-conjugated IHC, WB WB Suggested Anti-ABCB1 Antibody Titration: 0.2-1 ug/mlELISA Titer: 1:62500Positive Control: NCI-H226 cell lysate 100 μL Log in to see 2 to 3 Days
$289.00
Details
Human Mouse Un-conjugated FACS, IHC (fro), IF, IHC (p), IP   0.1 mg Log in to see 6 to 8 Days
$335.50
Details
Human Mouse PE FACS   100 Tests Log in to see 6 to 8 Days
$456.50
Details
Human Rabbit Un-conjugated IHC (fro), IHC (p) Anti-P Glycoprotein Picoband antibody,  IHC(P): Mouse Kidney Tissue Anti-P Glycoprotein Picoband antibody,  IHC(F): Rat Kidney Tissue 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Rabbit Un-conjugated IHC, IHC (p) Immunohistochemistry: MDR1/ABCB1 Antibody [NBP1-90291] - Immunohistochemical staining of human liver shows cytoplasmic positivity in hepatocytes. 0.1 mL Log in to see 8 to 11 Days
$439.69
Details

ABCB1 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Antibodies

  1. Dog (Canine) Monoclonal ABCB1 Primary Antibody for BP, ICC - ABIN153083 : van Den Elsen, Kuntz, Hoedemaeker, Rose: Antibody C219 recognizes an alpha-helical epitope on P-glycoprotein. in Proceedings of the National Academy of Sciences of the United States of America 2000 (PubMed)
    Show all 11 references for ABIN153083

  2. Dog (Canine) Polyclonal ABCB1 Primary Antibody for EIA, WB - ABIN401371 : Baker, Johnstone, Zalcberg, El-Osta: Epigenetic changes to the MDR1 locus in response to chemotherapeutic drugs. in Oncogene 2005 (PubMed)
    Show all 6 references for ABIN401371

  3. Human Monoclonal ABCB1 Primary Antibody for FACS - ABIN317070 : Beck, Grogan, Willman, Cordon-Cardo, Parham, Kuttesch, Andreeff, Bates, Berard, Boyett, Brophy, Broxterman, Chan, Dalton, Dietel, Fojo, Gascoyne, Head, Houghton, Srivastava, Lehnert, Leith, Paietta et al.: Methods to detect P-glycoprotein-associated multidrug resistance in patients' tumors: consensus recommendations. ... in Cancer research 1996 (PubMed)
    Show all 2 references for ABIN317070

  4. Human Monoclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1724927 : Zhang, Wang, Cai, Jiang, Zhou, Yang, Chen, Chen, Dou: Downregulation of gene MDR1 by shRNA to reverse multidrug-resistance of ovarian cancer A2780 cells. in Journal of cancer research and therapeutics 2012 (PubMed)
    Show all 2 references for ABIN1724927

  5. Human Monoclonal ABCB1 Primary Antibody for IHC (fro), IF - ABIN1106124 : Callen, Baker, Simmers, Seshadri, Roninson: Localization of the human multiple drug resistance gene, MDR1, to 7q21.1. in Human genetics 1987 (PubMed)
    Show all 2 references for ABIN1106124

  6. Human Polyclonal ABCB1 Primary Antibody for ELISA, WB - ABIN1043891 : Al-Shawi, Omote: The remarkable transport mechanism of P-glycoprotein: a multidrug transporter. in Journal of bioenergetics and biomembranes 2006 (PubMed)

  7. Human Monoclonal ABCB1 Primary Antibody for FACS, IHC (fro) - ABIN317069 : Mechetner, Roninson: Efficient inhibition of P-glycoprotein-mediated multidrug resistance with a monoclonal antibody. in Proceedings of the National Academy of Sciences of the United States of America 1992 (PubMed)

More Antibodies against ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 Interaction Partners

Cow (Bovine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. P-gp (show ABCB4 Antibodies), Bcrp (show ABCG2 Antibodies) and Mrp1 (show ABCC1 Antibodies) are functionally expressed in bovine/rat co-culture model and model is suitable for investigations of small molecule transport.

  2. This study has, for the first time, confirmed the expression of ABCB1 in epithelial cells of the bovine rumen.

  3. Bovine blastocysts stimulated by the combined treatment with forskolin, rifampicin, and interferon-alpha to express high levels of ATP-binding cassette subfamily B member 1 displayed better freezing resistance

  4. ABCB1 is expressed in bovine oocytes and embryos.

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. results suggest that some Japanese non-small-cell lung cancer patients treated with crizotinib developed clinically significant toxicities that were related to altered pharmacokinetics parameters due to ABCB1 polymorphism and body weight factors

  2. The ABCB1 gene polymorphism 3435C>T may be linked to individual differences in response to latanoprost eye drops treatment in primary open-angle glaucoma patients.

  3. The aims of this research were to investigate the association of TPMT (show TPMT Antibodies) phenotypes with MDR1 (show TBC1D9 Antibodies) genotypes.

  4. UCA1 functions as a competitive endogenous (ceRNA) of MDR1 (show TBC1D9 Antibodies) through completely binding the common miR-16 (show GDE1 Antibodies)

  5. Single nucleotide polymorphism C3435T (rs1045642) within MDR1 (show TBC1D9 Antibodies) gene may be associated with an increased expression of P-gp (show ABCB4 Antibodies) which affects the levels of antiepileptic drugs in plasma. The presented studies analysed the association between C3435T polymorphism of MDR1 (show TBC1D9 Antibodies) gene and the incidence of drug-resistant epilepsy in the population of Polish children.

  6. found that the MDR1 (show TBC1D9 Antibodies) C3435T polymorphisms did not play an important role as a genetic risk factor for the development and progression of childhood ITP (show ITPA Antibodies). However, patients carrying MDR1 (show TBC1D9 Antibodies) (CC) genotypes had a higher risk to develop childhood ITP (show ITPA Antibodies) at an older age and having lower initial platelet count than patients carrying other genotype

  7. We analyzed TNFalpha (show TNF Antibodies), NOS 3 (show NANOS3 Antibodies) and MDR1 (show TBC1D9 Antibodies) in 77 patients with MM and 77 healthy controls. The genotyping was performed with PCR and/or PCR-RFLP.

  8. ABCB1 gene variants could affect the pharmacodynamics of rocuronium.

  9. C3435T polymorphism in the MDR1 (show TBC1D9 Antibodies) gene appears not to be associated with sustained virological response in HCV-HIV co-infected individuals.

  10. The expression of ABCB1, ABCC1 (show ABCC1 Antibodies) and ABCG2 (show ABCG2 Antibodies) on primary human T-cells correlates with the efficacy of JAK (show JAK3 Antibodies) inhibitor ruxolitinib treatment in regard to T-cell activation and proliferation.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) interaction partners

  1. Pgp (show ABCB4 Antibodies)-coupled ATPase (show DNAH8 Antibodies) activity kinetics measured with a range of verapamil and digoxin concentrations fit well to a DDI model encompassing non-competitive and competitive inhibition of digoxin by verapamil.

  2. Data show that human transgenic mutant huntingtin (show HTT Antibodies) (mHtt) aggregation might be regulated by multidrug resistance protein 1 (MDR1 (show ABCB4 Antibodies)) which suggests that MDR1 (show ABCB4 Antibodies) might be a potential therapeutic target for Huntington's disease.

  3. In vitro and in vivo downregulation of the ATP binding cassette transporter (show ABCC3 Antibodies) B1 by the HMG-CoA reductase (show HMGCR Antibodies) inhibitor simvastatin

  4. Efficient chemoprotection of CDD (show CDA Antibodies) and MDR1 (show ABCB4 Antibodies) transduced hematopoietic 32D as well as primary lin(-) cells was proven in the context of Ara (show FOXC1 Antibodies)-C and anthracycline application

  5. These study data have facilitated understanding of the molecular mechanisms of neurotoxicosis in ABCB1-1Delta mutant mice following exposure to various P-gp (show ABCB4 Antibodies) substrates.

  6. Data indicate that the brain penetration of ABT-888 in both Abcb1a (show ABCB4 Antibodies)/1b-/- and Abcb1a (show ABCB4 Antibodies)/1b-/-;Abcg2 (show ABCG2 Antibodies)-/- mice was significantly higher than in wild-type mice.

  7. Expression of Abcb1 at the blood-brain and blood-spinal barriers is upregulated by Nrf2 (show NFE2L2 Antibodies).

  8. The improved structures of Pgp reveal important implications for polyspecific drug recognition in the form of a high concentration of aromatic residues in the drug translocation pathway that is most conserved among mammalian orthologs.

  9. Real-time polymerase chain reaction for ABC (show ABCB6 Antibodies) transporters demonstrated that Abcb1a (show ABCB4 Antibodies), Abcb1b (show ABCB4 Antibodies) and Abcg2 (show ABCG2 Antibodies), regarded as stem cell markers, were characteristically expressed in TtT/GF cells but not in Tpit (show TBX19 Antibodies)/F1 and LbetaT2 cells.

  10. In addition to ABCB1-mediated transport.

ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 1 (ABCB1) Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.

Gene names and symbols associated with ABCB1

  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (ABCB1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1 (abcb1) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1A (Abcb1a) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 1B (Abcb1b) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 1B (Abcb1b) antibody
  • malic enzyme complex, mitochondrial (Mod2) antibody
  • ABC20 antibody
  • ABCB1 antibody
  • Cd243 antibody
  • CLCS antibody
  • GP170 antibody
  • Mdr antibody
  • Mdr-1 antibody
  • Mdr1 antibody
  • Mdr1a antibody
  • Mdr1b antibody
  • Mod-2 antibody
  • Mod-2r antibody
  • Mod-2s antibody
  • Mod2-r antibody
  • Mod2-s antibody
  • p-gp antibody
  • PGP1 antibody
  • Pgy-1 antibody
  • Pgy1 antibody
  • xemdr antibody

Protein level used designations for ABCB1

bovine P-glycoprotein , multidrug resistance protein 1 , multidrug resistance protein , ATP-binding cassette sub-family B member 1 , P-glycoprotein 1 , colchicin sensitivity , doxorubicin resistance , ATP-binding cassette, subfamily B, member 1 , P-glycoprotein , multidrug resistance p-glycoprotein , ATP-binding cassette, sub-family B (MDR/TAP), member 1 , ATP-binding cassette, subfamily B (MDR/TAP), member 1A , multiple drug resistant 1a , P glycoprotein 1 , multidrug resistance protein 1B , ATP-binding cassette sub-family B (MDR/TAP) member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1 (P-glycoprotein/multidrug resistance 1) , ATP-binding cassette, sub-family B (MDR/TAP), member 1B , ATP-binding cassette, subfamily B, member 1B , P-glycoprotein/multidrug resistance 1 , malic enzyme complex, mitochondrial , malic enzyme, mitochondrial regulatory , malic enzyme, mitochondrial structural

GENE ID SPECIES
281585 Bos taurus
397812 Xenopus laevis
463516 Pan troglodytes
5243 Homo sapiens
403879 Canis lupus familiaris
170913 Rattus norvegicus
100682536 Cricetulus griseus
18669 Mus musculus
24646 Rattus norvegicus
110357 Mus musculus
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