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anti-ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) Antibodies

The membrane-associated protein encoded by ABCB11 is a member of the superfamily of ATP-binding cassette (ABC) transporters. Additionally we are shipping ABCB11 Kits (14) and ABCB11 Proteins (7) and many more products for this protein.

list all antibodies Gene Name GeneID UniProt
ABCB11 8647 O95342
ABCB11 27413 Q9QY30
ABCB11 83569 O70127
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Top anti-ABCB11 Antibodies at antibodies-online.com

Showing 10 out of 52 products:

Catalog No. Reactivity Host Conjugate Application Images Quantity Supplier Delivery Price Details
Human Rabbit Un-conjugated EIA, IHC (p), WB 0.4 mL Log in to see 6 to 8 Days
$390.50
Details
Human Rabbit Un-conjugated IHC (p), WB The anti-ABCB11 C-term Pab (ABIN390059) is used in Western blot to detect ABCB11 in mouse liver tissue lysate. Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. BC = breast carcinoma. HC = hepatocarcinoma 400 μL Log in to see 10 to 11 Days
$324.50
Details
Human Rabbit Un-conjugated IHC (p), WB Anti- ABCB11 Picoband antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti- ABCB11 Picoband antibody, Western blotting All lanes: Anti ABCB11  at 0.5ug/ml Lane 1: Rat Liver Tissue Lysate at 50ug Lane 2: Mouse Liver Tissue Lysate at 50ug Lane 3: SMMC Whole Cell Lysate at 40ug Predicted bind size: 146KD Observed bind size: 146KD 100 μg Log in to see 4 to 6 Days
$240.00
Details
Human Rabbit Un-conjugated IHC (p), WB Anti-ABCB11 antibody, IHC(P) IHC(P): Human Liver Cancer Tissue Anti-ABCB11 antibody, Western blotting Lane 1: Rat Liver Tissue Lysate Lane 2: SMMC Cell Lysate Lane 3: M231 Cell Lysate 100 μg Log in to see 4 to 6 Days
$200.00
Details
Human Mouse Un-conjugated ICC, IHC (p), WB Human Liver (formalin-fixed, paraffin-embedded) stained with ABCB11 antibody ABIN305775 at 5 ug/ml followed by biotinylated anti-mouse IgG secondary antibody ABIN481714, alkaline phosphatase-streptavidin and chromogen. 50 μg Log in to see 8 to 10 Days
$595.83
Details
Human Rabbit Un-conjugated ICC, IF, IHC (p), WB ICC/IF Image BSEP antibody [N3C1], Internal detects ABCB11 protein at membrane by immunofluorescent analysis. Sample: A431 cells were fixed in ice-cold MeOH for 5 min. Green: ABCB11 protein stained by BSEP antibody [N3C1], Internal , diluted at 1:500. Blue: Hoechst 33343 staining. WB Image Sample (30 ug of whole cell lysate) A: JurKat 5% SDS PAGE antibody diluted at 1:1000 100 μL Log in to see 2 to 3 Days
$358.60
Details
Human Rabbit Un-conjugated ELISA   100 μg Log in to see 8 to 10 Days
$434.50
Details
Human Rabbit Un-conjugated IHC, WB 400 μL Log in to see 6 Days
$457.14
Details
Human Rabbit Un-conjugated IF (p), IHC (p), WB Formalin-fixed and paraffin embedded rat pancreatic tissue labeled with Anti-BSEP/ABCB11 Polyclonal Antibody, Unconjugated (ABIN675848) at 1:200 followed by conjugation to the secondary antibody and DAB staining 100 μL Log in to see 3 to 7 Days
$269.50
Details
Human Rabbit Un-conjugated IHC (p), WB   100 μg Log in to see 8 to 10 Days
$463.83
Details

ABCB11 Antibodies by Reactivity, Application, Clonality and Conjugate

Attributes Applications Host Clonality Conjugate
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Top referenced anti-ABCB11 Antibodies

  1. Human Polyclonal ABCB11 Primary Antibody for EIA, IHC (p) - ABIN358589 : Chen, Chang, Hsu, Ni, Hsu, Lee, Jeng, Shau, Chang: FIC1 and BSEP defects in Taiwanese patients with chronic intrahepatic cholestasis with low gamma-glutamyltranspeptidase levels. in The Journal of pediatrics 2002 (PubMed)
    Show all 3 references for ABIN358589

  2. Human Polyclonal ABCB11 Primary Antibody for IHC (p), WB - ABIN390059 : Strautnieks, Bull, Knisely, Kocoshis, Dahl, Arnell, Sokal, Dahan, Childs, Ling, Tanner, Kagalwalla, Németh, Pawlowska, Baker, Mieli-Vergani, Freimer, Gardiner, Thompson: A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis. in Nature genetics 1998 (PubMed)
    Show all 3 references for ABIN390059

More Antibodies against ABCB11 Interaction Partners

Rainbow Trout (Oncorhynchus mykiss) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. Data show the gene expression profiling of ABC (show ABCB6 Antibodies) transporters in seven tissues.

  2. cloned one partial and two full gene sequences, which show high degree of identity with mammalian Pgp1 (ABCB1 (show ABCB1 Antibodies)), BSEP (ABCB11) and MRP2 (ABCC2 (show ABCC2 Antibodies)) efflux transporters and found identical relative expression patterns for both liver and primary hepatocytes

Human ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. Results identified six novel mutations (PKHD1 (show PKHD1 Antibodies): p.Thr777Met, p.Tyr2260Cys; ABCB11: p.Val1112Phe, c.611+1G > A, p.Gly628Trpfs*3 and NPC1 (show NPC1 Antibodies): p.Glu391Lys) for the diagnostic of inherited infantile cholestatic disorders.

  2. Report highly specific expression of BSEP and MDR3 (show ABCB4 Antibodies) in hepatocellular carcinoma.

  3. GGT levels in patients with ATP8B1 or ABCB11 deficiency varied with age. The peak GGT value was <70U/L in the 2nd~6th month of life, <60U/L in the 7th~12th month and <50U/L beyond one year

  4. methods that can be used to assess and quantify BSEP inhibition, and key gaps in our current understanding of the relationship between this process and DILI, are discussed

  5. Liver nuclear receptors, FXR (show NR1H4 Antibodies) and SHP (show LAMC1 Antibodies), and bile acid transporters, NTCP (show SLC10A1 Antibodies) and BSEP, are associated with the progression of NAFLD (show TSC2 Antibodies).

  6. ABCB11 444A had slightly reduced transport activity.

  7. Similar molecular features between MRP4 (show ABCC4 Antibodies) and BSEP inhibitors may partially explain why various drugs have affinity for both transporters.

  8. In malignant tumours in the liver, BSEP marking was 100% specific and 90% sensitive for hepatocellular carcinoma.

  9. The aim of this study was the evaluation of some single nucleotide polymorphisms of genes (ABCB1 (show ABCB1 Antibodies), SLC28A2 (show SLC28A2 Antibodies)/3, SLC29A1 (show SLC29A1 Antibodies)) involved in telaprevir (TLV) and ribavirin transport and their correlation with plasma TLV drug exposure at 1 month of therapy.

  10. Aberrant splicing of ABCB11 in the liver of progressive familial intrahepatic cholestasis type 2 patients.

Mouse (Murine) ATP-Binding Cassette, Sub-Family B (MDR/TAP), Member 11 (ABCB11) interaction partners

  1. Isoniazid/rifampicin administration significantly down-regulated the expression of hepatic bile acids transporters Ntcp (show SLC10A1 Antibodies) and Bsep in liver.

  2. mechanism of increased biliary lipid secretion in Bsep-/- mice is based on increased expression of the responsible canalicular transporter proteins.

  3. LKB1 (show STK11 Antibodies)/AMPK (show PRKAA1 Antibodies) and PKA control ABCB11 trafficking and polarization in hepatocytes.

  4. CA feeding of Bsep (-/-) mice increased hepatic Cyp3a11 protein levels.

  5. FXR (show NR1H4 Antibodies) regulates BSEP in an isoform-dependent and species-specific manner

  6. Ursodeoxycholic acid fed to abcb11-/- mice caused liver damage and the appearance of biliary tetra- and penta-hydroxy bile acids.

  7. Hepatic Abcb11 overexpression in mice increases the conservation of bile acids within the enterohepatic circulation.

  8. The authors show that two of these transporters, ABCB11 and ATP8B1 (show ATP8B1 Antibodies), are functional targets of miR (show MLXIP Antibodies)-33, a micro-RNA that is expressed from within an intron of SREBP-2 (show SREBF2 Antibodies).

  9. Abcb11 deficiency induces cholestasis coupled to impaired beta-fatty acid oxidation in mice.

  10. hyperosmotic cholestasis is triggered by a NADPH oxidase (show NOX1 Antibodies)-driven reactive oxygen species formation that mediates Fyn (show FYN Antibodies)-dependent retrieval of the Mrp2 (show ABCC2 Antibodies) and Bsep from the canalicular membrane, which may involve an increased cortactin (show CTTN Antibodies) phosphorylation.

ABCB11 Antigen Profile

Protein Summary

The membrane-associated protein encoded by this gene is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. The protein encoded by this gene is the major canalicular bile salt export pump in man. Mutations in this gene cause a form of progressive familial intrahepatic cholestases which are a group of inherited disorders with severe cholestatic liver disease from early infancy.

Gene names and symbols associated with ABCB11

  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (ABCB11) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (abcb11) antibody
  • bile salt export pump (EDI_111220) antibody
  • bile salt export pump (EDI_272930) antibody
  • bile salt export pump (abcb11) antibody
  • ATP-binding cassette, sub-family B (MDR/TAP), member 11 (Abcb11) antibody
  • ATP-binding cassette, subfamily B (MDR/TAP), member 11 (Abcb11) antibody
  • ABC16 antibody
  • ABCB11 antibody
  • BRIC2 antibody
  • BSEP antibody
  • BSEP/SPGP antibody
  • Lith1 antibody
  • PFIC-2 antibody
  • PFIC2 antibody
  • PGY4 antibody
  • Spgp antibody

Protein level used designations for ABCB11

ATP-binding cassette, sub-family B (MDR/TAP), member 11 , bile salt export pump , bile salt export pump-like , ABC member 16, MDR/TAP subfamily , ATP-binding cassette sub-family B member 11 , progressive familial intrahepatic cholestasis 2 , sister p-glycoprotein , ATP-binding cassette, sub-family B, member 11 , sister of P-glycoprotein , liver bile salt export pump

GENE ID SPECIES
424170 Gallus gallus
470717 Pan troglodytes
488390 Canis lupus familiaris
531150 Bos taurus
100024107 Monodelphis domestica
100052359 Equus caballus
100083318 Ornithorhynchus anatinus
100404882 Callithrix jacchus
100454135 Pongo abelii
100473353 Ailuropoda melanoleuca
100489744 Xenopus (Silurana) tropicalis
100518154 Sus scrofa
100543935 Meleagris gallopavo
100565276 Anolis carolinensis
100590891 Nomascus leucogenys
5879080 Entamoeba dispar SAW760
5914265 Entamoeba dispar SAW760
100136688 Oncorhynchus mykiss
100337637 Cavia porcellus
8647 Homo sapiens
27413 Mus musculus
100008767 Oryctolagus cuniculus
83569 Rattus norvegicus
Selected quality suppliers for anti-ABCB11 (ABCB11) Antibodies
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